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MNS (3,4-methylenedioxy-beta-nitrostyrene) prevented platelet aggregation caused by various stimulators, and this action was accompanied by inhibition of tyrosine kinases. Synonyms: 3,4-Methylenedioxy-beta-nitrostyrene; Syk Inhibitor III; NSC 170724; 5-(2-Nitrovinyl)benzodioxole. Grades: 98%. CAS No. 1485-00-3. Molecular formula: C9H7NO4. Mole weight: 193.16.
MNS
MNS. Group: Biochemicals. Grades: Purified. CAS No. 1485-00-3. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
MNS
MNS (NSC 170724), the beta-nitrostyrene derivative, is an orally active tyrosine kinase inhibitor and a broad-spectrum antiplatelet agent. MNS inhibits Src, Syk, and FAK with IC 50 of 27.3, 2.8, and 97.6 μM, respectively. MNS inhibits NLRP3 inflammasome and β1 integrin. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC 50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 μM, respectively. MNS is cytotoxic to a variety of cells [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 170724; 5-(2-Nitrovinyl)benzodioxole. CAS No. 1485-00-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-78263.
Anti-Superoxide Dismutase (MnSOD) (DD-17) antibody produced in rabbit
Acid Yellow 110. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acid Yellow 110;Yellow 110 275%;C.I. Acid Yellow 110;Acid Milling Yellow 5GN;Acid Yellow MNS;Aminyl Yellow E 5GN;Benzyl Fast Yellow GC;Kemacid Yellow 110. Product Category: Acid Dyes. CAS No. 12220-74-5. Product ID: ACM12220745. Alfa Chemistry ISO 9001:2015 Certified.
Adaptaquin
Adaptaquin is an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase 2 (PHD2) with IC50 value of 2 μM in a reporter assay using SH-SY5Y-ODD-Luc cells. It displays neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models by inhibition of ATF4 dependent genes. It reduces neuronal death and behavioral deficits after intracerebral hemorrhage (ICH) in several rodent models. It blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. It stabilizes HIF-1α protein and induces expression of the HIF1-regulated genes EPO and VEGF in SH-SY5Y human neuroblastoma cells. It is used in ischemic injury research, renal anemia, and used as an antioxidant. It is also used in pyruvate dehydrogenase (PDH) related research. Synonyms: 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol. Grades: ≥97% by HPLC. CAS No. 385786-48-1. Molecular formula: C21H16ClN3O2. Mole weight: 377.82.
Imisopasem manganese
Imisopasem manganese is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. Synonyms: M40403; M 40403; M 40403; CG4419; CG 4419; CG-4419; SC-72325; SC72325; SC 72325. Grades: >98%. CAS No. 218791-21-0. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.39.
Manganese (II) Sulfate
MANGANESE (II) SULFATE, MONOHYDRATE, 99.5% pure, -8 mesh, Formula: MnSO4.H2O. CAS No. 10034-96-5. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!
Texas TX
Manganese (II) Sulfate
MANGANESE (II) SULFATE, MONOHYDRATE, 99.9% pure, -8 mesh, Formula: MnSO4.H2O. CAS No. 10034-96-5. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!
Texas TX
Manganese (II) Sulfate
MANGANESE (II) SULFATE, MONOHYDRATE, ACS Reagent, crystalline, Formula: MnSO4.H2O. CAS No. 10034-96-5. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!
Manganese(II) Sulfate Hydrate ?99.99% trace metals basis. CAS No. 10034-96-5. Molecular Formula MnSO4 * H2O. Ultra High Purity Fine Chemicals
Cater Chemicals Corp. Illinois IL
Manganese(II)sulfide
Manganese(II)sulfide. Uses: Designed for use in research and industrial production. Product Category: Metal & Ceramic Materials. CAS No. 18820-29-6. Molecular formula: MnS. Mole weight: 87.003049. Product ID: ACM18820296. Alfa Chemistry ISO 9001:2015 Certified. Categories: Manganese(II) sulfide.
Manganese Silicide (1:2 Atomic)
MANGANESE SILICIDE (1:2 atomic), 99.5% pure, -325 mesh, (Synonym: Manganese Disilicide), Formula: MnSi2. CAS No. 12032-86-9. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!
Texas TX
Manganese stannate
Manganese stannate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MANGANESE STANNATE. Product Category: Heterocyclic Organic Compound. CAS No. 12209-35-7. Molecular formula: MnSnO. Mole weight: 221.65. Product ID: ACM12209357. Alfa Chemistry ISO 9001:2015 Certified.
Manganese Sulfate Monohydrate. CAS No. 10034-96-5. Molecular Formula MnSO4 * H2O. Chemical Reagents
Cater Chemicals Corp. Illinois IL
Manganese Sulphate BP/USP (Monohydrate)
Manganese Sulphate BP/USP (Monohydrate). CAS No. 10034-96-5. Molecular formula: MnSO4.H2O.
Manganese Sulphate USP (Anhydrous)
Manganese Sulphate USP (Anhydrous). CAS No. 7785-87-7. Molecular formula: MnSO4.
Pterostilbene
A natural stilbenoid related to Resveratrol. Displays anti-oxidative, anti-cancer, anti-hypercholesterolemia, and anti-hypertriglyceridemia properties. Pterostilbene alters gene expression in pancreatic cancer and increases the antiproliferative markers cytochrome C, Smac/DIABLO, and MnSOD/antioxidant activity. It was also shown to inhibit phosphorylated STAT3, a marker of accelerated tumorigenesis, and decrease pancreatic tumor growth in vivo. Group: Biochemicals. Alternative Names: 4-[ (E) -2- (3, 5-Dimethoxyphenyl) ethenyl]phenol; 3',5'-Dimethoxy-4-stilbenol. Grades: Highly Purified. CAS No. 537-42-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Superoxide Dismutase 2 from Human, Recombinant
SOD2 is part of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in SOD2 gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. SOD2 destroys radicals which are usually produced within the cells and which are toxic to biological systems. Group: Enzymes. Synonyms: Superoxide dismutase [Mn]; mitochondrial; IPOB; MNSOD; MVCD6. Enzyme Commission Number: EC 1.15.1.1. Purity: > 95% by SDS-PAGE. SOD. Mole weight: 24.4 kDa (219 aa, 25-222 aa + His Tag). Activity: > 1,200 units/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at - 20°C or -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: E. coli. Species: Human. Superoxide dismutase [Mn]; mitochondrial; IPOB; MNSOD; MVCD6; Superoxide Dismutase 2; SOD-2; Mn-SOD; Mn Superoxide dismutase. Cat No: NATE-1658.
Zonisamide
Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with K i s of 35.2 and 20.6 nM for hCA II and hCA V , respectively. Zonisamide exerts neuroprotective effects through anti- apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1 , thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinsons disease and cardiac hypertrophy [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD 810; CI 912. CAS No. 68291-97-4. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-B0124.
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