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| Product | Description | |
|---|---|---|
| Mocetinostat | Mocetinostat. Group: Biochemicals. Alternative Names: N- (2-Aminophenyl) -4- [ [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] methyl] benzamide; MG 0103; MGCD 0103. Grades: Highly Purified. CAS No. 726169-73-9. Pack Sizes: 10mg. Molecular Formula: C23H20N6O, Molecular Weight: 396.44. US Biological Life Sciences. |  Worldwide |
| Mocetinostat | Mocetinostat is a rationally designed, orally available, Class 1-selective, small molecule, 2-aminobenzamide HDAC inhibitor with potential antineoplastic activity. Mocetinostat binds to and inhibits Class 1 isoforms of HDAC, specifically HDAC 1, 2 and 3, which may result in epigenetic changes in tumor cells and so tumor cell death; although the exact mechanism has yet to be defined, tumor cell death may occur through the induction of apoptosis, differentiation, cell cycle arrest, inhibition of DNA repair, upregulation of tumor suppressors, down regulation of growth factors, oxidative stress, and autophagy, among others. Overexpression of Class I HDACs 1, 2 and 3 has been found in many tumors and has been correlated with a poor prognosis. Synonyms: MGCD-0103; MGCD 0103; MGCD0103. Grades: >98%. CAS No. 726169-73-9. Molecular formula: C23H20N6O. Mole weight: 396.454. |  |
| Mocetinostat | Mocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC 50 s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1 , HDAC2 , HDAC3 and HDAC11 , respectively. Mocetinostat shows no inhibition on HDAC4, HDAC5, HDAC6, HDAC7, or HDAC8. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD0103. CAS No. 726169-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12164. |  |
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