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| Product | Description | |
|---|---|---|
| Motesanib | Motesanib (AMG 706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC 50 s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG 706. CAS No. 453562-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10228. |  |
| Motesanib | Motesanib is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors. It also potently inhibits angiogenesis and induces regression in tumor xenografts. Uses: Protein kinase inhibitors. Synonyms: N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4- ylmethyl)amino]pyridine-3-carboxamide; AMG 706; AMG706; AMG706; motesanib. Grades: >98%. CAS No. 453562-69-1. Molecular formula: C22H23N5O. Mole weight: 373.45. |  |
| Motesanib | Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma. Group: Biochemicals. Alternative Names: N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide. Grades: Highly Purified. CAS No. 453562-69-1. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Motesanib diphosphate | Motesanib diphosphate. Group: Biochemicals. Alternative Names: N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide phosphate; AMG 706. Grades: Highly Purified. CAS No. 857876-30-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C22H29N5O9P2. US Biological Life Sciences. | Worldwide |
| Motesanib Diphosphate | Motesanib Diphosphate is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. Uses: Protein kinase inhibitors. Synonyms: Motesanib diphosphate; 857876-30-3; AMG-706; Motesanib (Diphosphate); Motesanib Diphosphate (AMG-706); Motesanib diphosphate [USAN]; Motesanib phosphate; AMG 706 (Diphosphate); AMG 706; ; T6Q3060U91; Motesanib phosphate (JAN); Motesanib diphosphate (USAN); N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide; phosphoric acid; MOTESANIB PHOSPHATE [JAN]; 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-, phosphate (1:2). Grades: >98%. CAS No. 857876-30-3. Molecular formula: C22H29N5O9P2. Mole weight: 569.44. | |
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