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| Product | Description | |
|---|---|---|
| Moxonidine hydrochloride | ?98%. Group: Fluorescence/luminescence spectroscopy. |  |
| Moxonidine hydrochloride | Moxonidine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 75536-04-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Moxonidine hydrochloride | Moxonidine hydrochloride is a mixed agonist of α2-adrenergic receptor (α2AR) and imidazoline-1 receptor(I1R). Its Ki values is 4.2±3.2 nmol/L, 13.0±4.2 nmol/L, 9.5±4.1 nmol/L and 15.6±9.8 nmol/L for I1R, α2AAR, α2BAR and α2CAR, respectively. It is used as antihypertensive agent. It displays 40-fold higher affinity for I1 receptors versus α2-adrenoceptors. It reduced stimulated NE overflow (log EC50: -6.15 +/- 0.14). It has been reported to produce dose-dependent analgesia in multiple acute pain assays and has been reported to potently inhibit the binding of [3H]-clonidine to VLM (ventrolateral medulla) membranes in a dose-dependent manner with the IC50 value of 53 ± 10nM. It has shown low affinity for I2-relative to I1R sites in bovine adrenal medullary cells. Uses: Moxonidine hydrochloride is used as antihypertensive agent. it has been reported to produce dose-dependent analgesia in multiple acute pain assays and has been reported to potently inhibit the binding of [3h]-clonidine to vlm (ventrolateral medulla) membranes in a dose-dependent manner with the ic50 value of 53 ± 10nm. Synonyms: BDF5895 hydrochloride; BDF 5895 hydrochloride; BDF-5895 hydrochloride; 4-Chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-yl)aminopyrimidine hydrochloride. Grades: 98%. CAS No. 75536-04-8. Molecular formula: C9H13Cl2N5O. Mole weight: 278.14. |  |
| Moxonidine hydrochloride | Moxonidine Hydrochloride is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BDF5895 hydrochloride. CAS No. 75536-04-8. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-B0374A. |  |
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