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| Product | Description | |
|---|---|---|
| MPEP | MPEP is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC 50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects [1] [2]. MPEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 96206-92-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14609A. |  |
| MPEP hydrochloride | MPEP hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 219911-35-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| MPEP Hydrochloride | MPEP Hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC 50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects [1] [2]. MPEP (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 219911-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14609. | |
| MPEP Hydrochloride (6-Methyl-2- (phenylethynyl) pyridine Hydrochloride) | A non-competitive, highly potent antagonist selective for mGlu5 receptors (IC50 = 36nM). Also a positive allosteric modulator of mGlu4 and weak anatagonist of nMDA receptors. Biologically active admitted systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as learning and memory, sleep, neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 96206-92-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-Methyl-6- (phenylethynyl) pyridine, Hydrochloride (MPEP) | A potent, subtype selective mGluR5 antagonist. Group: Biochemicals. Alternative Names: MPEP. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Mmpep | Mmpep. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[(3-Methoxyphenyl)ethynyl]-6-methylpyridine Hydrochloride; M-MPEP Hydrochloride. Product Category: Heterocyclic Organic Compound. CAS No. 823198-78-3. Molecular formula: C15H14ClNO. Mole weight: 259.73. Purity: 0.96. IUPACName: 2-[2-(3-methoxyphenyl)ethynyl]-6-methylpyridine;hydrochloride. Canonical SMILES: CC1=CC=CC(=N1)C#CC2=CC(=CC=C2)OC.Cl. Product ID: ACM823198783. Alfa Chemistry ISO 9001:2015 Certified. Categories: MMPIP. |  |
| 2-Methyl-6-[ (3-methoxyphenyl) ethynyl]pyridine hydrochloride | 2-Methyl-6-[ (3-methoxyphenyl) ethynyl]pyridine hydrochloride. Group: Biochemicals. Alternative Names: 2-[(3-Methoxyphenyl)ethynyl]-6-methylpyridine hydrochloride; M-MPEP hydrochloride. Grades: Highly Purified. CAS No. 823198-78-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C15H14ClNO. US Biological Life Sciences. | Worldwide |
| BMT-145027 | BMT-145027 is a potent mGluR5 PAM without inherent agonist activity with an EC50 of 47 nM. BMT-145027 is a non-MPEP site PAM to demonstrate in vivo efficacy. Synonyms: BMT-145027; BMT 145027; BMT145027; 3-[4-chloro-3-(trifluoromethyl)phenyl]-4-cyclopropyl-6-phenyl-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile. CAS No. 2018282-44-3. Molecular formula: C23H14ClF3N4. Mole weight: 438.83. |  |
| MTEP | Potent and selective antagonist for mGluR5. 5-fold higher anxiolytic activity than MPEP. Antidepressant. Neuroprotective. Produces anti-parkinsonian-like effects in rats. Group: Biochemicals. Alternative Names: 3-pyridine. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C11H8N2S. US Biological Life Sciences. | Worldwide |
| VU0364289 | VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP (HY-14609A) site), with an EC 50 of 1.6 μM. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1242443-29-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120727. | |
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