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| Product | Description | |
|---|---|---|
| Mps1-IN-1 | Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM; >1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk. Synonyms: Mps1-IN-1; 1125593-20-5; 1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol; 1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]piperidin-4-ol; 1MPS1-IN-1; 3gfw; 1-(4-((4-((2-(isopropylsulfonyl)phenyl)amino)-1H-pyrrolo[2,3-b]pyridin-6-yl)amino)-3-methoxyphenyl)piperidin-4-ol; MLS003230944; GTPL9271; SCHEMBL4051419; CHEMBL1235786; BDBM36485; CHEBI:91379; DTXSID60649015; AVB59320; BCP27688; AKOS027422816; CS-3776; NCGC00387463-01; NCGC00387463-04; HY-13298; MS-29898; SMR001913509; F85109; A925638; J-503190; Q27087728; 1-(3-methoxy-4-{[4-({2-[(1-methylethyl)sulfonyl]phenyl}amino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino}phenyl)piperidin-4-ol; 1-[3-Methoxy-4-({4-[2-(propane-2-sulfonyl)anilino]-1H-pyrrolo[2,3-b]pyridin-6-yl}amino)phenyl]piperidin-4-ol; s22. Grades: >98%. CAS No. 1125593-20-5. Molecular formula: C28H33N5O4S. Mole weight: 535.66. |  |
| Mps1-IN-1 dihydrochloride | Mps1-IN-1 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Mps1-IN-1 dihydrochloride | Mps1-IN-1 is a selective inhibitor of monopolar spindle 1 (Mps1) kinase (IC50 = 367 nM), which displays >1000 fold-selectivity against a panel of 352 kinases with the exceptions of ALK and Ltk. Synonyms: 1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1883548-93-3. Molecular formula: C28H35Cl2N5O4S. Mole weight: 608.58. | |
| Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers)Mps1-IN-1 dihydrochloride | Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers)Mps1-IN-1 dihydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092813-99-4. Pack Sizes: 50MG. IUPAC Name: (2S)-2-[(3S)-3-(4-aminobutyl)-1,4-dioxo-6,7,8,8a-tetrahydro-3H-pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoic acid. Molecular Formula: C21H29N3O4. Mole Weight: 387.47. Catalog: APS1092813994A. SMILES: NCCCC[C@@H]1N ([C@@H] (CCc2ccccc2)C (=O)O)C (=O)C3CCCN3C1=O. Format: Neat. Shipping: Room Temperature. |  |
| Mps1-IN-3 | MPS1-IN-3 is a selective and potent MPS1 inhibitor with phenotypic consequences similar to those reported for published MPS1 inhibitors such as MPS1-IN-1, MPS1-IN-2, and AZD3146. Treatment with MPS1-IN-3 at 5 μM sensitized all glioblastoma cells to 3 nM of vincristine as measured by cell counts 11 days posttreatment. U251-FM cells were stereotactically injected into the brain of nude mice. Ten days postinjection, 2 mg/kg of MPS1-IN-3 and/or 0.5 mg/kg of vincristine were administered concomitantly by intravenous injections twice per week for 3 weeks. Synonyms: Mps1-IN-3; Mps1 IN3; Mps1-IN3. Grades: >98%. CAS No. 1609584-72-6. Molecular formula: C26H31N7O4S. Mole weight: 537.63. | |
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