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A dopaminergic neurotoxin that causes permanent symptoms of Parkinson's disease by killing certain neurons in the substantia nigra of the brain. Useful tool compound for Parkinson's disease related studies. Synonyms: MPTP. Grades: >98%. CAS No. 23007-85-4. Molecular formula: C12H16ClN. Mole weight: 209.72.
MPTP hydrochloride is a brain penetrant dopamine neurotoxin. MPTP hydrochloride can be used to induces Parkinsons Disease model. MPTP hydrochloride, a precusor of MPP + , induces apoptosis [1] [2] [3]. MPTP hydrochloride has been verified by MCE with professional biological experiments. Uses: Scientific research. Group: Signaling pathways. CAS No. 23007-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15608.
A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson's disease models in primates. Group: Biochemicals. Grades: Highly Purified. CAS No. 23007-85-4. Pack Sizes: 10mg. Molecular Formula: C??H??N·HCl. US Biological Life Sciences.
The active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) , N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Group: Biochemicals. Alternative Names: 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine Hydrochloride. Grades: Highly Purified. CAS No. 1012886-75-7. Pack Sizes: 25mg. US Biological Life Sciences.
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Adrogolide hydrochloride
Adrogolide hydrochloride (ABT-431 hydrochloride) is a chemically stable prodrug that can convert to the dopamine D1 receptor agonist A-86929. Adrogolide hydrochloride ameliorates the MPTP (HY-15608)-induced Parkinson's Disease in marmoset model, reduces the dyskinesias tendency. Adrogolide hydrochloride reverses Risperidone (HY-11018)-induced cognitive deficits in monkey [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-431 hydrochloride; DAS-431 hydrochloride. CAS No. 166591-11-3. Pack Sizes: 1 mg. Product ID: HY-118956.
Bifemelane hydrochloride
Bifemelane hydrochloride is a MAO inhibitor displaying antidepressant activity. Bifemelane reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets. Bifemelane has the potential to treat cerebral infarction and Alzheimer's disease for its neuroprotective and nootropic effects. Uses: Antidepressant. Synonyms: Celeport; Alnert; 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 62232-46-6. Molecular formula: C18H23NO.HCl. Mole weight: 305.84.
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