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MRT-83 hydrochloride MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1359944-60-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18287A. MedChemExpress MCE
MRT-83 hydrochloride MRT-83 is a Smoothened (Smo) antagonist. It can block Hedgehog (Hh) signaling in various assays. MRT-83 can also inhibit Bodipy-cyclopamine binding to human and mouse Smo. MRT-83 can efficiently antagonize Hh signaling in vivo. MRT-83 may help develop new therapies for the treatment of Hh-pathway related diseases. Uses: Hh-pathway related diseases. Synonyms: MRT-83 hydrochloride; MRT 83 hydrochloride; MRT83 hydrochloride; N-(2-methyl-5-(3-(3,4,5-trimethoxybenzoyl)guanidino)phenyl)-[1,1'-biphenyl]-4-carboxamide hydrochloride;1263131-92-5 (free base). Grades: 98%. CAS No. 1359944-60-7. Molecular formula: C31H31ClN4O5. Mole weight: 575.06. BOC Sciences 10

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