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Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide , consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDP. CAS No. 53678-77-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127090.
2-Dodecyltetradecanoic Acid Methyl-d3 Ester
2-Dodecyltetradecanoic Acid Methyl-d3 Ester is the labeled analogue of 2-Dodecyltetradecanoic Acid Methyl Ester (D441790), which is a reactant used in the synthesis of muramyldipeptide lipophilic derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C27H51D3O2, Molecular Weight: 413.73. US Biological Life Sciences.
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2-Dodecyltetradecanoic Acid Methyl Ester
2-Dodecyltetradecanoic Acid Methyl Ester is a reactant used in the synthesis of muramyldipeptide lipophilic derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 167083-39-8. Pack Sizes: 100mg, 1g. Molecular Formula: C27H54O2, Molecular Weight: 410.72. US Biological Life Sciences.
Worldwide
Adjuvant Peptide
Adjuvant Peptide is an immunomodulatory factor that can be used as a vaccine adjuvant to enhance immune response. It inhibits HIV replication in CD4+H9 lymphocytes. Uses: Adjuvants, immunologic. Synonyms: D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-; D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-; N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutamine; Acetylmuramoyl-L-alanyl-D-isoglutamine; MDP; MDP-D; Muramoyl dipeptide; N-(Acetylmuramoyl)-L-alanyl-D-isoglutamine; N-(Acetylmuramoyl)alanyl-D-isoglutamine; N-Acetylmuramoyl dipeptide; N-Acetylmuramoyl-L-alanine-D-isoGln; N-Acetylmuramoylalanyl-D-isoglutamine; (4R,5R,7R,10S,13R)-13-carbamoyl-4-formyl-7,10-dimethyl-2,8,11-trioxo-5-((1R,2R)-1,2,3-trihydroxypropyl)-6-oxa-3,9,12-triazahexadecan-16-oic acid; N-Ac-Mur-Ala-D-Glu-NH2; N-Acetylmuramyl-L-Ala-D-Glu-NH2; Muramyl dipeptide. Grades: ≥95%. CAS No. 53678-77-6. Molecular formula: C19H32N4O11. Mole weight: 492.48.
Almurtide
Almurtide, also known as romurtide, is a synthetic muramyl dipeptide (MDP) H8analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects. Synonyms: CGP 11637; CGP11637; CGP-11637; norMDP; N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine. CAS No. 61136-12-7. Molecular formula: C18H30N4O11. Mole weight: 478.46.
Lysostaphin
Lysostaphin is an antistaphylococcal agent. Lysostaphin has activities of three enzymes namely, glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9011-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2329.
Mifamurtide
Mifamurtide is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. It is a derivative of the mycobacterial cell wall component MDP and activates both monocytes and macrophages. It is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. It has orphan drug status for the treatment of osteosarcoma in the US and EU. Synonyms: Mepact; CGP-19835; CGP 19835; CGP19835; MTP-PE; MTP-cephalin; L-MTP-PE; MLV19835. Grades: >98%. CAS No. 83461-56-7. Molecular formula: C59H109N6O19P. Mole weight: 1237.50.
Mifamurtide
Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE; L-MTP-PE; CGP 19835. CAS No. 83461-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13682.
Mifamurtide sodium
Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium. CAS No. 90825-43-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13682B.
The enzyme also works when the lysine residue is replaced by meso-2,6-diaminoheptanedioate (meso-2,6-diaminopimelate, A2pm) combined with adjacent residues through its L-centre, as it is in Gram-negative and some Gram-positive organisms. The undecaprenol involved is ditrans,octacis-undecaprenol (for definitions, click here). Group: Enzymes. Synonyms: MurG transferase; UDP-N-acetyl-D-glucosamine:N-acetyl-α-D-muramyl(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol β-1,4-N-acetylglucosaminlytransferase. Enzyme Commission Number: EC 2.4.1.227. CAS No. 60976-26-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2456; undecaprenyldiphospho-muramoylpentapeptide β-N-acetylglucosaminyltransferase; EC 2.4.1.227; 60976-26-3; MurG transferase; UDP-N-acetyl-D-glucosamine:N-acetyl-α-D-muramyl(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol β-1,4-N-acetylglucosaminlytransferase. Cat No: EXWM-2456.
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