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| Product | Description | |
|---|---|---|
| Muramyl dipeptide | Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide , consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDP. CAS No. 53678-77-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127090. |  |
| Adjuvant Peptide | Adjuvant Peptide is an immunomodulatory factor that can be used as a vaccine adjuvant to enhance immune response. It inhibits HIV replication in CD4+H9 lymphocytes. Uses: Adjuvants, immunologic. Synonyms: D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-; D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-; N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutamine; Acetylmuramoyl-L-alanyl-D-isoglutamine; MDP; MDP-D; Muramoyl dipeptide; N-(Acetylmuramoyl)-L-alanyl-D-isoglutamine; N-(Acetylmuramoyl)alanyl-D-isoglutamine; N-Acetylmuramoyl dipeptide; N-Acetylmuramoyl-L-alanine-D-isoGln; N-Acetylmuramoylalanyl-D-isoglutamine; (4R,5R,7R,10S,13R)-13-carbamoyl-4-formyl-7,10-dimethyl-2,8,11-trioxo-5-((1R,2R)-1,2,3-trihydroxypropyl)-6-oxa-3,9,12-triazahexadecan-16-oic acid; N-Ac-Mur-Ala-D-Glu-NH2; N-Acetylmuramyl-L-Ala-D-Glu-NH2; Muramyl dipeptide. Grades: ≥95%. CAS No. 53678-77-6. Molecular formula: C19H32N4O11. Mole weight: 492.48. |  |
| Almurtide | Almurtide, also known as romurtide, is a synthetic muramyl dipeptide (MDP) H8analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects. Synonyms: CGP 11637; CGP11637; CGP-11637; norMDP; N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine. CAS No. 61136-12-7. Molecular formula: C18H30N4O11. Mole weight: 478.46. | |
| GSK717 | GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1595278-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136555. | |
| Mifamurtide | Mifamurtide is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. It is a derivative of the mycobacterial cell wall component MDP and activates both monocytes and macrophages. It is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. It has orphan drug status for the treatment of osteosarcoma in the US and EU. Synonyms: Mepact; CGP-19835; CGP 19835; CGP19835; MTP-PE; MTP-cephalin; L-MTP-PE; MLV19835. Grades: >98%. CAS No. 83461-56-7. Molecular formula: C59H109N6O19P. Mole weight: 1237.50. | |
| Mifamurtide | Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE; L-MTP-PE; CGP 19835. CAS No. 83461-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13682. | |
| Mifamurtide sodium | Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium. CAS No. 90825-43-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13682B. | |
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