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| Product | Description | |
|---|---|---|
| Muristerone A | Muristerone A, a phytoecdysteroid analog of ecdysone, acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Synonyms: (2β, 3β, 5β, 11α, 22R)-2, 3, 5, 11, 14, 20, 22-Heptahydroxycholest-7-en-6-one; Mur A. Grades: ≥97% by HPLC. CAS No. 38778-30-2. Molecular formula: C27H44O8. Mole weight: 496.63. |  |
| Muristerone A | Muristerone A is a potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to Ponasterone A. Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals.Induces apoptosis in cells transfected with wild-type Bax. Induces expression of beta-galactosidase. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Insect steroid hormone involved in regulating metamorphosis, causing a response to G2 cell cycle arrest. Major molting hormone in some insects. Has protective effects in plants.Source:Ipomoea hederacea seeds. Group: Biochemicals. Alternative Names: 2beta, 3beta, 5beta, 11alpha, 14alpha, 20R, 22R-Heptahydroxycholest-7-en-6-one. Grades: Highly Purified. CAS No. 38778-30-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C27H44O8, Method for Determining. US Biological Life Sciences. |  Worldwide |
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