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MV1 MV1 is an antagonist of IAP (inhibitor of apoptosis protein), leads to protein knockdown of HaloTag-fused proteins when combined with HaloTag ligand [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1001600-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113534. MedChemExpress MCE
MV1 MV1 is an IAP antagonist. IAP are a family of functionally and structurally related proteins that serve as endogenous inhibitors of programmed cell death (apoptosis). Synonyms: MV-1; MV 1. Grades: 98%. CAS No. 1001600-54-9. Molecular formula: C33H44N4O5. Mole weight: 576.7. BOC Sciences 9
MV151 MV151 is a fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. MV151 specifically targets all active subunits of the proteasome and immunoproteasome in living cells, allowing for rapid and sensitive in-gel detection. The inhibition profile of a panel of commonly used proteasome inhibitors could be readily determined by MV151 labeling. Administration of MV151 to mice allowed for in vivo labeling of proteasomes, which correlated with inhibition of proteasomal degradation in the affected tissues. This probe can be used for many applications ranging from clinical profiling of proteasome activity, to biochemical analysis of subunit specificity of inhibitors, and to cell biological analysis of the proteasome function and dynamics in living cells. Synonyms: MV-151; MV 151; MV151; Bodipy TMR-Ahx(3)L(3)VS. Grades: 98%. CAS No. 945611-88-1. Molecular formula: C59H91BF2N8O9S. Mole weight: 1137.27. BOC Sciences 11
Balovaptan Balovaptan (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with K i s of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7314. CAS No. 1228088-30-9. Pack Sizes: 10 mM * 1ML; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109024. MedChemExpress MCE
Phenylalanine,N-acetyl-,2-naphthalenyl ester Phenylalanine,N-acetyl-,2-naphthalenyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: beta-naphthyl N-acetylphenylalaninate; APNE; N-Acetyl-DL-phenylalanin-[2]naphthylester; N-acetyl-DL-phenylalanine-[2]naphthyl ester; naphthalen-2-yl 2-acetamido-3-phenylpropanoate; mv1. Product Category: Heterocyclic Organic Compound. CAS No. 20874-31-1. Molecular formula: C21H19NO3. Mole weight: 333.38. Purity: 0.96. IUPACName: naphthalen-2-yl 2-acetamido-3-phenylpropanoate. Canonical SMILES: CC(=O)NC(CC1=CC=CC=C1)C(=O)OC2=CC3=CC=CC=C3C=C2. Density: 1.2g/cm³. Product ID: ACM20874311. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
Proteasome Inhibitor XXI, Z-LLLL-SF (Cbz-Leu-Leu-Leu-Leu-Psi-[CH2SO2]-F, Cbz-Leu4-SF, Cbz-LLLL-SF, Z-Leu4-SF, Z-L4-SF) A cell-permeable tetrapeptidyl sulfonyl fluoride -based irreversible proteasome inhibitor that selectively inhibits the hydrolysis of Suc-LLVY-AMC by the beta5 chymotrypsin-like activity (IC50 = 7nM using yeast 20S proteasome), while exhibiting much reduced potency against Z-LLE-AMC hydrolysis by the beta1 caspase-like activity or Z-LLR-AMC hydrolysis by the beta2 trypsin-like activity (29% and 75% inhibition, respectively, with 200uM inhibitor). One hour inhibitor treatment at 5uM in HEK cultures is shown to completely abolish beta5 labeling by the proteasome probe MV151, while only partial MV151 blockage is seen with beta1 and beta2 at an inhibitor concentration of 50uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??FN?O?S. US Biological Life Sciences. USBiological 4
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