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| Product | Description | |
|---|---|---|
| N-Arachidonylglycine | N-Arachidonylglycine has been isolated from cell cultures treated with arachidonoyl ethanolamide. It is a GPR18 agonist with EC50 value of 44.5 nM. It is a kind of endogenous anandamide-like compound. It is also an endogenous GlyT2 inhibitor and acts as a glycine transporter inhibitor. It has also been synthesized as an analog of AEA for structure/activity testing. It may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. It has analgesic activities in whole animal experiments. Synonyms: N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine; Arachidonyl Glycine; (all-Z)-N-(1-Oxo-5,8,11,14-eicosatetraenyl)glycine; N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraenyl]glycine. Grades: ≥98% by HPLC. CAS No. 179113-91-8. Molecular formula: C22H35NO3. Mole weight: 361.52. |  |
| N-Arachidonylglycine | N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist ( EC 50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 ( IC 50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: NA-Gly. CAS No. 179113-91-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103332. |  |
| N-Arachidonylglycine-d8 | N-Arachidonylglycine-d8 is a deuterated labeled N-Arachidonylglycine [1]. N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist ( EC 50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 ( IC 50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: NA-Gly-d8. CAS No. 1159908-44-7. Pack Sizes: 1 mg (2.71 mM * 1 mL in Ethanol). Product ID: HY-103332S. | |
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