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| Product | Description | |
|---|---|---|
| N2-Methylguanosine | 2-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, the DNA becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Synonyms: N-Methylguanosine; Guanosine, N-methyl-; 2-Methylguanosine; 9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(methylamino)-1H-purin-6(9H)-one; N2-Methylguanine riboside; 2-(methylamino)-9-(beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; m2G. Grades: ≥95%. CAS No. 2140-77-4. Molecular formula: C11H15N5O5. Mole weight: 297.27. |  |
| N2-Methylguanosine | N2-Methylguanosine. Group: Biochemicals. Alternative Names: m2G. Grades: Highly Purified. CAS No. 2140-77-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C11H15N5O5. US Biological Life Sciences. |  Worldwide |
| 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-methylguanosine 3'-CE phosphoramidite | 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-methylguanosine 3'-CE phosphoramidite is an invaluable compound in the field of compound, playing a pivotal role as a foundation for constructing modified nucleotides. By incorporating the N2-methylguanosine modification into oligonucleotides, this phosphoramidite enhances both stability and targeting functionalities, thereby facilitating the application of disease-specific reserchs. Synonyms: 2'-TBDMS-5'-Dimethoxytrityl-N2-methyl-guanosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C47H64N7O8PSi. Mole weight: 914.11. | |
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