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| Product | Description | |
|---|---|---|
| 6α-Naloxol | Cas No. 20410-95-1. |  |
| 6b-Naloxol HCl | 6b-Naloxol HCl. Group: Biochemicals. Alternative Names: (5a,6b)-4,5-Epoxy-17-(2-propenyl)morphinan-3,6,14-triol hydrochloride. Grades: Highly Purified. CAS No. 55488-85-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C19H23NO4·HCl. US Biological Life Sciences. |  Worldwide |
| Naloxegol | Naloxegol is a CYP3A4 enzyme inhibitor. It is also a peripherally-selective opioid antagonist. It is used as the treatment of opioid-induced constipation. lt is a pegylated (polyethylene glycol-modified) derivative of α-naloxol and can be used to reduce opioid-induced symptoms. lt binds to and blocks mu-opioid receptors in the peripheral nervous system. It would reverse the effects of opiate drugs of abuse if it entered the central nervous system. It was approved in 2014 in adult patients with chronic, non-cancer pain. lt was developed by AstraZeneca, licensed from Nektar Therapeutics. It was approved in 2014 in adult patients with chronic, non-cancer pain. It has been listed. Uses: Naloxegol is used as the treatment of opioid-induced constipation. lt can be used to reduce opioid-induced symptoms. Synonyms: Movantik;NKTR-118; NKTR 118; NKTR118; (4R, 4aS, 7S, 7aR, 12bS) -7- [2- [2- [2- [2- [2- [2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] -3-prop-2-enyl-1, 2, 4, 5, 6, 7, 7a, 13-octahydro-4, 12-methanobenzofuro [3, 2-e] isoquinoline-4a, 9-diol. Grades: >98%. CAS No. 854601-70-0. Molecular formula: C34H53NO11. Mole weight: 651.78. | |
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