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A unique collection of 3720 naturalproducts that can be used for high-throughput screening and high-content screening. - Provides biological information and pharmacological information of the products, which serve as theoretical references and research basis for screening. - Clear source: a selection of known active naturalproducts from animals, plants and microorganisms; plant species are labeled with accurate English and Latin names to facilitate your later research corroboration. - Good structural diversity: a wide range of compound structures including flavonoids and alkaloids, with detailed classification information. - NMR, HPLC/LCMS and other detection techniques to ensure the correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L6010. Categories: NaturalProduct Libraries.
NaturalProductLibrary for HTS
A unique collection of 4160 pure naturalproducts and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can be used for high throughput screening (HTS) and high content screening (HCS); - Documentation with clear source: isolated naturalproducts from plant, animal, microorganism, etc. - Structurally diverse: 4160 naturalproducts, including diverse types of structures, such as alkaloids, limonoids, sequiterpenes, diterpenes, pentacyclic triterpenes, sterols, and many other representatives which provide the structural diversity inherent in this group; - Detailed compound information with structure, solubility, target, activity, IC50 value, and biological activity description; - Cost-effective and competitive price to save your fundings. Uses: Scientific use. Product Category: L6000. Categories: NaturalProduct Libraries for HTS.
Alkaloid NaturalProductLibrary
A unique collection of 317 natural alkaloids can be used for high throughput and high content screening?- Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6110. Categories: Alkaloid NaturalProduct Libraries.
Anti-Gastroenteritis NaturalProductLibrary
A unique collection of 223 naturalproducts related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); - Effective tool for research in gastric function and gastric diseases, such as gastritis, gastric ulceration, Crohns disease, ulcerative colitis, appendicitis, etc. - Bioactivity and safety profiled in pre-clinical and clinical settings; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6600. Categories: Anti-Gastroenteritis NaturalProduct Libraries.
Anti-Tumor NaturalProductLibrary
A unique collection of 1471 naturalproducts with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Known bioactivity for all compounds: detailed biological and pharmacological information, providing the research foundation and theoretical direction for screening; - Clear source: known active naturalproducts selected from animals, plants, or microorganisms with clear species information; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Cost-effectiveness: expensive naturalproducts with poor drug likeliness are excluded, allowing for more high-quality naturalproducts at a lower cost. Uses: Scientific use. Product Category: L6700. Categories: Anti-Tumor NaturalProduct Libraries.
Covalent NaturalProductLibrary
Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening. - Clear source: a selection of known active naturalproducts from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research. - Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information. - Cost-effective: eliminates expensive naturalproducts with poor drug-forming properties, allowing you to get more high-quality naturalproducts at a lower cost. - Highly customizable with free combination according to naturalproduct source, naturalproduct category, research area, drug market status, etc. Uses: Scientific use. Product Category: L6150. Categories: Covalent NaturalProduct Libraries.
Flavonoid NaturalProductLibrary
A unique collection of 252 flavonoids can be used for high throughput and high content screening?- Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6120. Categories: Flavonoid NaturalProduct Libraries.
Microbial NaturalProductLibrary
A unique collection of 193 microbial naturalproducts for high throughput screening (HTS) and high content screening (HCS); - Targets include alpha-glucosidase, beta-lactamase, TNF-alpha, HDAC, PKC, HSP90, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6500. Categories: Microbial NaturalProduct Libraries.
NaturalProduct Derivatives Library
The library consists of more than 4, 000 members belonging 22 scaffolds (average 180 compounds per scaffold). - The library includes the following sub-libraries:- Cytisine-based sub-library- Matrine-based sub-library- Podophyllotoxin-based sub-library- Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc. - TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members). - NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc. ). - More than 90% purity for each library member confirmed by LC-MS or NMR analysis. Uses: Scientific use. Product Category: NY1000. Categories: NaturalProduct Derivatives Libraries.
NaturalProduct Derivatives Library for CADD
Large quantity: contains 135, 000 naturalproduct derivatives and the number is continuously updating. Uses: Scientific use. Product Category: L6030. Categories: NaturalProduct Derivatives Libraries for CADD.
Polyphenolic NaturalProductLibrary
A unique collection of 411 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include JAK, AMPK, CYP, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6100. Categories: Polyphenolic NaturalProduct Libraries.
RO5 Drug-like NaturalProductLibrary
2743 is a collection of naturalproducts that meet the "Lipinski's Rule of Five" and have high potential for drug discovery. - Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more. - Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories. - Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives. Uses: Scientific use. Product Category: L6160. Categories: RO5 Drug-like NaturalProduct Libraries.
Saccharide and Glycoside NaturalProductLibrary
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS?- An effective tool for saccharide drugs development; - Contains a variety of Chinese medicine active ingredients with strong bioactivities such as anti-oxidative, antitumor, and anti-inflammatory effects, etc. ?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6140. Categories: Saccharide and Glycoside NaturalProduct Libraries.
Selectable NaturalProductLibrary
A unique collection of 19377 pure naturalproducts with diverse structures and sources covering various plant, animal, and microbe species; - Free SDF data available for each compound structure in this library, an effective tool for virtual screening; - All products can be resupplied; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6020. Categories: Selectable NaturalProduct Libraries.
Terpene NaturalProductLibrary
A unique collection of 349 natural terpenes and terpenoids can be used for high throughput and high content screening?- Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6130. Categories: Terpene NaturalProduct Libraries.
High Solubility 3D Diversity Fragment Library
Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this context, Fragment-based drug design (FBDD) came into being. Organic synthesis can transform miniature hits into effective lead compounds. The deficiencies in the current screening of compound libraries usually result in the need for a large amount of synthetic investment to achieve multi-directional fragment growth, which limits the efficiency of the mini-fragment hit modification process. To meet this challenge, we designed a library of highly soluble 3D structural diversity fragments. The utility of X-ray-based fragment screening and the ability to achieve rapid analog synthesis: Uses: Scientific use. Product Category: L7850. Categories: High Solubility 3D Diversity Fragment Libraries.
High Solubility Polyfunctional Group Fragment Library
Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this ... are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. The high solubility multifunctional fragment library is designed by analyzing the spatial stability of all commercially available fragments and selecting a chemically diverse subset. In order to enhance the diversity of the compound library, we carefully selected some additional saturated heterocyclic compounds to supplement the compound library. Uses: Scientific use. Product Category: L7810. Categories: High Solubility Polyfunctional Group Fragment Libraries.
Natural Compound Library in Chinese Pharmacopoeia
A unique collection of 2070 naturalproducts included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study; - Diversified structures: including flavonoids, polyphenols, Alkaloids, etc. ; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Clear source: known active naturalproducts selected from animals, plants, or microorganisms with clear species information; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6800. Categories: Natural Compound Libraries in Chinese Pharmacopoeia.
Oxidation-Reduction Compound Library
A unique collection of 1279 compounds with defined prooxidant or antioxidant activity can be used for HTS and HCS; - Contains hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase, and antioxidant naturalproducts, etc. ?- Structurally diversified with potent bioactivity and cell permeable; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2900. Categories: Oxidation-Reduction Compounds Libraries.
Rare Natural Compound Library
A unique collection of 284 rare naturalproducts, which can be used for high throughput screening (HTS) and high content screening (HCS); - Documentation with clear source: isolated naturalproducts from plant, animal, microorganism, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6900. Categories: Rare Natural Compounds Libraries.
Selected Plant-Sourced Compound Library
A unique collection of 2720 plant-sourced compounds; - All are in preclinical or clinical research phases with the most research potential; - Includes many popular naturalproducts, such as Artemisinin, Ginsenoside, etc. ; - Structurally diverse, medicinally active, and cell permeable; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4600. Categories: Selected Plant-Sourced Compounds Libraries.
Tibetan medicine Compound Library
A collection of 239 naturalproduct molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening. - Sources include Cordyceps, Rhodiola, Saffron, Tianshan Snow Lotus, Ganoderma and other precious herbs. - Structural diversity, significant medicinal effects and easy cell penetration. - Various detection techniques such as NMR, HPLC/LCMS ensures the correct structure and high purity of the products and reduce false-positive rates. Uses: Scientific use. Product Category: L6210. Categories: Tibetan medicine Compounds Libraries.
Toxic Compound Library
A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS); - Covers more than 150 targets related to immune diseases, neurological diseases, respiratory disorders, endocrine diseases, and cardiovascular diseases. - Includes 222 drugs with certain studies on mechanisms of toxicity; - Includes 89 naturalproducts, most of which are effective ingredients of Chinese medicine and attractive for toxicological study. - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5500. Categories: Toxic Compounds Libraries.
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