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| Product | Description | |
|---|---|---|
| NAV 26 | NAV 26 (compound 26) is a selective voltage-gated sodium channel Nav1.7 blocker with an IC 50 of 0.37 μM. NAV 26 can be used for pain research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1198160-14-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118048. |  |
| NAV 26 | NAV 26. Group: Biochemicals. Grades: Purified. CAS No. 1198160-14-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Navitoclax (ABT 263) | A novel inhibitor of antiapoptotic BCL-2 proteins; a new. Group: Biochemicals. Alternative Names: 4- [4- [ [2- (4-Chlorophenyl) -5, 5-dimethyl-1-cyclohexen-1-yl] methyl] -1-piperazinyl] -N- [ [4- [ [ (1R) -3- (4-morpholinyl) -1- [ (phenylthio) methyl] propyl] amino] -3- [ (trifluoromethyl) sulfonyl] phenyl] sulfonyl] benzamide; Navitoclax. Grades: Highly Purified. CAS No. 923564-51-6. Pack Sizes: 5mg, 10mg, 50mg, 100mg. Molecular Formula: C??H??ClF?N?O?S?, Molecular Weight: 974.61. US Biological Life Sciences. | Worldwide |
| 2, 3-Dihydro-3-oxo-2- (tetrahydro-2H-pyran-4-yl) -N-[[4- (trifluoromethoxy) phenyl]methyl]-1H-Isoindole-1-carboxamide | 2, 3-Dihydro-3-oxo-2- (tetrahydro-2H-pyran-4-yl) -N-[[4- (trifluoromethoxy) phenyl]methyl]-1H-Isoindole-1-carboxamide also known as NAV 26, is a potent and state-dependant blocker of sodium gated voltage channels with application towards pain relief. Analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1198160-14-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C22H21F3N2O4, Molecular Weight: 434.41. US Biological Life Sciences. | Worldwide |
| ABT 263-[d8] | ABT 263-[d8] is a labelled ABT 263. ABT 263, also named Navitoclax, is an orally active, synthetic small molecule and an antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. Synonyms: 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide-d8. CAS No. 1217620-38-6. Molecular formula: C47H47D8ClF3N5O6S3. Mole weight: 982.66. |  |
| ACID BLUE 113 | ACID BLUE 113. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACID BLUE 113;CI 26360;COOMASSIE NAVY BLUE 2RN;1-naphthalenesulfonicacid,8-(phenylamino)-5-[[4-[(3-sulfophenyl)azo]-1-naphth;1-Naphthalenesulfonicacid,8-(phenylamino)-5-[[4-[(3-sulfophenyl)azo]-1-naphthalenyl]azo]-,disodiumsalt;AcidCyanine5R;Aciddeepblue. Product Category: Acid Dyes. Appearance: dark blue powder. CAS No. 3351-5-1. Molecular formula: C32H21N5Na2O6S2. Mole weight: 681.64. Density: g/cm³. Product ID: ACM3351051. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Benzonatate | Benzonatate is a reversible voltage-gated sodium channel blocker, which is also known as Tessalon and KM-65. Benzonatate's mechanism of action is thought to be anesthesia of vagal sensory nerve fibers that mediate cough. Benzonatate also blocks 80% of Nav1.3 currents in N1E-115 cells when used at a concentration of 100 μM. Synonyms: Benzoic acid, 4-(butylamino)-, 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester; Benzoic acid, p-(butylamino)-, 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl ester; Benzoic acid, p-(butylamino)-, ester with 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-ol; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl 4-(butylamino)benzoate; Benzononantin; Benzononatine; Exangit; KM 65; Tesalon; Tessalin; Tessalon; Tessalon-Ciba; Ventussin; Ventussin-Loz. Grade: ≥98%. CAS No. 104-31-4. Molecular formula: C30H53NO11. Mole weight: 603.74. | |
| DISPERSE BLUE 26 | DISPERSE BLUE 26. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,5-dihydroxy-4,8-bis(methylamino)-10-anthracenedione;10-Anthracenedione,1,5-dihydroxy-4,8-bis(methylamino)-9;1,5-dihydroxy-4,8-bis(methylamino)anthraquinone;c.i.63305;C.I.DISPERSEBLUE26;NAVILENEBLUE;Disperse blue 26 (C.I. 63305);9, 10-Anthracenedione, 1, 5-dihydroxy-4, 8-bis(methylamino). Product Category: Disperse Dyes. CAS No. 3860-63-7. Molecular formula: C16H14N2O4. Mole weight: 298.29336. Product ID: ACM3860637. Alfa Chemistry ISO 9001:2015 Certified. | |
| Huwentoxin IV | Huwentoxin IV is a selective NaV1.7 channel blocker with preference for neuronal NaV1.7, 1.2 and 1.3 (IC50 = 26, 150 and 338 nM, respectively). Huwentoxin IV inhibits the channel via binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration. Synonyms: HWTX-IV; H-Glu-Cys(1)-Leu-Glu-Ile-Phe-Lys-Ala-Cys(2)-Asn-Pro-Ser-Asn-Asp-Gln-Cys(3)-Cys(1)-Lys-Ser-Ser-Lys-Leu-Val-Cys(2)-Ser-Arg-Lys-Thr-Arg-Trp-Cys(3)-Lys-Tyr-Gln-Ile-NH2; L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-alpha-glutamyl-L-isoleucyl-L-phenylalanyl-L-lysyl-L-alanyl-L-cysteinyl-L-asparagyl-L-prolyl-L-seryl-L-asparagyl-L-alpha-aspartyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-seryl-L-seryl-L-lysyl-L-leucyl-L-valyl-L-cysteinyl-L-seryl-L-arginyl-L-lysyl-L-threonyl-L-arginyl-L-tryptophyl-L-cysteinyl-L-lysyl-L-tyrosyl-L-glutaminyl-L-isoleucinamide (2->17),(9->24),(16->31)-tris(disulfide). Grade: >99%. CAS No. 526224-73-7. Molecular formula: C174H278N52O51S6. Mole weight: 4106.79. | |
| Navlimetostat | Navlimetostat is a potent, orally active, selective PRMT5-MTA complex inhibitor, with IC50 of 3.6 and 20.5 nM for PRMT5-MTA and PRMT5. Navlimetostat binds to the PRMT5-MTA complex, with KD value of 0.14 pM. Navlimetostat shows antineoplastic activity in vitro and in vivo, and can be used for cancer study[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MRTX-1719. CAS No. 2630904-45-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139611. | |
| (S)-Navlimetostat | (S)-Navlimetostat (example 16-7) is the S-enantiomer of Navlimetostat. (S)-Navlimetostat is a PRMT5/MTA complex inhibitor, with an IC 50 of 7070 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-MRTX-1719. CAS No. 2630904-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139611B. | |
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