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| Product | Description | |
|---|---|---|
| NCB-0846 | NCB-0846 is an orally active, selective inhibitor for Wnt , that inhibits Traf2- and Nck-interacting kinase ( TNIK ) with an IC 50 of 21?nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1792999-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100830. |  |
| NCB-0846 | NCB-0846 is an orally available, first-in-class TNIK inhibitor (IC50 = 21?nM) and shows marked anti-tumour and anti-CSC activities. Synonyms: NCB-0846; NCB 0846; NCB0846; 4-[2-(3H-benzimidazol-5-ylamino)quinazolin-8-yl]oxycyclohexan-1-ol. CAS No. 1792999-26-8. Molecular formula: C21H21N5O2. Mole weight: 375.42. |  |
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