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NCGC00244536 KDM4B-IN-B3, also know as NCGC00244536, is a novel KDM4 inhibitor. KDM4B-IN-B3 inhibits the in vivo growth of tumors derived from PC3 cells and ex vivo human PCa explants. Histone lysine demethylase KDM4/JMJD2s are overexpressed in many human tumors including prostate cancer (PCa). Uses: Designed for use in research and industrial production. Additional or Alternative Names: KDM4B-IN-B3; KDM4B IN B3; KDM4BINB3; NCGC00244536; NCGC-00244536; NCGC 00244536. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2003260-55-5. Molecular formula: C25H22N2O2. Mole weight: 382.46. Purity: >98%. IUPACName: 3-(8-Hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide. Canonical SMILES: O=C(NCCCC1=CC=CC=C1)C2=CC=CC(C3=CC(O)=C4N=CC=CC4=C3)=C2. Product ID: ACM2003260555. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
NCGC00244536 NCGC00244536 is a potent KDM4A inhibitor (IC50 = 10 nM) that inhibits the in vivo growth of tumors derived from PC3 cells and ex vivo human PCa explants. Synonyms: KDM4B-IN-B3; KDM4B IN B3; KDM4BINB3; 3-(8-hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide; CHEMBL3785491; BDBM50158844. CAS No. 2003260-55-5. Molecular formula: C25H22N2O2. Mole weight: 382.45. BOC Sciences 8

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