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| Product | Description | |
|---|---|---|
| NCT-503 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| NCT-503 | NCT-503 is a non-competitive phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50= 2.5 μM), reducing the production of glucose-derived serine in cells and suppressing the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors. Synonyms: NCT-503; NCT 503; NCT503. N- (4, 6-dimethylpyridin-2-yl) -4-[[4- (trifluoromethyl) phenyl]methyl]piperazine-1-carbothioamide. CAS No. 1916571-90-8. Molecular formula: C20H23F3N4S. Mole weight: 408.48. |  |
| NCT-503 Inactive Control | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PHGDH-inactive | PHGDH-inactive is an inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503. It can be used as a negative control for NCT-502 and NCT-503. Synonyms: 3-Phosphoglycerate Dehydrogenase-inactive; N-(4,6-dimethylpyridin-2-yl)-4-pyridin-4-ylpiperazine-1-carbothioamide. Grades: ≥98%. CAS No. 1914971-16-6. Molecular formula: C17H21N5S. Mole weight: 327.5. | |
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