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| Product | Description | |
|---|---|---|
| Nefazodone | Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT 2A receptors , and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83366-66-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119209. |  |
| NEFAZODONE | Nefazodone is a selective serotonin 5-HT2 receptor antagonist. It is an antidepressant under the development of Bristol-Myers Squibb. Its sale was discontinued in some countries due to the rare incidence of hepatotoxicity. Uses: Antidepressant. Synonyms: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one; 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one; 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-; BMY-13754; 1-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one. Grades: 95%. CAS No. 83366-66-9. Molecular formula: C25H32ClN5O2. Mole weight: 470.01. |  |
| Nefazodone HCl | Nefazodone hydrochloride is a selective serotonin 5-HT2 receptor antagonist. It is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. It is a phenylpiperazin derivative, whose structure is similar to that of some known antidepressants. It was developed by Bristol-Myers Squibb. Uses: Nefazodone hydrochloride is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. Synonyms: BMY 13754; BMY13754; BMY-13754; Dutonin; Nefazodone HCl; Rulivan; MJ 13754 1; MJ-13754-1; MJ137541. 3H-1,2,4-Triazol-3-one, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride;Nefazodone HCl;BMY-13754;MJ-13754-1;2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride;2,4-Dihydro-2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride; Serzone; Dutonin; Menfazona. Grades: 95%. CAS No. 82752-99-6. Molecular formula: C25H33Cl2N5O2. Mole weight: 506.46. | |
| Nefazodone hydrochloride | Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A ( K i =5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake ( IC 50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-13754; MJ-13754-1. CAS No. 82752-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1396. | |
| Nefazodone hydrochloride | Nefazodone hydrochloride. CAS No: 82752-99-6 |  Sarchem Laboratories New Jersey NJ |
| Nefazodone hydrochloride | Nefazodone hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 82752-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Nefazodone, Hydrochloride (2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride) | A selective serotonin 5-HT2 receptor antagonist. An antidepressant. Group: Biochemicals. Alternative Names: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Nefazodone Hydrochloride (5-HT2A Serotonin Receptor Antagonist, Nefazodone, BMY-13754, MJ-13754-1, Serzone) | A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. CAS No. 82752-99-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nefazodone Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Nefazodone Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Hydroxy Nefazodone Dihydrochloride | A metabolite of Nefazodone , an antidepressant. Group: Biochemicals. Alternative Names: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-2,4-dihydro-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one Dihydrochloride. Grades: Highly Purified. CAS No. 98159-83-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Hydroxy Nefazodone HCl | | |
| Methoxymethoxy Nefazodone | Derivative of a Nefazodone metabolite used in the treatment of depression and other mental disorders. Group: Biochemicals. Alternative Names: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-2,4-dihydro-5-[1-(methoxymethoxy)ethyl]-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione | 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione, is a metabolite of Nefazodone (N389100), that has been shown to act as antidepressants that inhibit the serotonin (SERT) and norepinephrine transporters (NET). Group: Biochemicals. Grades: Highly Purified. CAS No. 153707-88-1. Pack Sizes: 5mg, 50mg. Molecular Formula: C23H28ClN5O3. US Biological Life Sciences. | Worldwide |
| 1-(3-(4-(4-Chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one Hydrochloride | 1-(3-(4-(4-Chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one Hydrochloride is an impurity in the synthesis of Nefazodone (N389100), a selective serotonin 5-HT2 receptor antagonist. A novel antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C25H33Cl2N5O2 HCl, Molecular Weight: 506.47. US Biological Life Sciences. | Worldwide |
| 1-(3-Bromopropyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-d5 | 1-(3-Bromopropyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-d5 is an intermediate in the synthesis of labelled Nefazodone (N389100), a selective serotonin 5-HT2 receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C15H14D6BrN3O2. US Biological Life Sciences. | Worldwide |
| 1- (3-Chlorophenyl) piperazine | It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone. Group: Biochemicals. Alternative Names: 1- (m-Chlorophenyl) piperazine; 4- (3-Chlorophenyl) piperazine; N- (3-Chlorophenyl) piperazine; N- (m-Chlorophenyl) piperazine; NSC 49307; mCPP. Grades: Highly Purified. CAS No. 6640-24-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 1- (3-Chlorophenyl) piperazine-d8 | It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone. Group: Biochemicals. Alternative Names: 1- (m-Chlorophenyl) piperazine-d8; 4- (3-Chlorophenyl) piperazine-d8; N- (3-Chlorophenyl) piperazine-d8; N- (m-Chlorophenyl) piperazine-d8; NSC 49307-d8; mCPP-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1- (3-Chlorophenyl) piperazine Hydrochloride | The major metabolite of Trazodone , Nefazodone , and Etoperidone. Group: Biochemicals. Alternative Names: 1- (m-Chlorophenyl) piperazine Hydrochloride; 4- (3-Chlorophenyl) piperazine Hydrochloride; N- (3-Chlorophenyl) piperazine Hydrochloride; N- (m-Chlorophenyl) piperazine Hydrochloride; mCPP Hydrochloride. Grades: Highly Purified. CAS No. 13078-15-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 2- (2- (Methoxymethoxy) propanoyl) -N- (2-phenoxyethyl) hydrazinecarboxamide | 2- (2- (Methoxymethoxy) propanoyl) -N- (2-phenoxyethyl) hydrazinecarboxamide is an intermediate in the synthesis of Nefazodone (N389100), a selective serotonin 5-HT2 receptor antagonist. A novel antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. Group: Biochemicals. Grades: Highly Purified. CAS No. 98159-87-6. Pack Sizes: 250mg, 2.5g. Molecular Formula: C14H21N3O5, Molecular Weight: 311.33. US Biological Life Sciences. | Worldwide |
| 2,4-Dihydro-5-[1-(methoxymethoxy)ethyl]-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one | Used in the preparation of Nefazodone. Group: Biochemicals. Grades: Highly Purified. CAS No. 98159-88-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2- (Methoxymethoxy) propanehydrazide | 2- (Methoxymethoxy) propanehydrazide is an intermediate in the synthesis of Hydroxy Nefazodone Hydrochloride (H948570), a metabolite of Nefazodone (N389100), an antidepressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 98159-92-3. Pack Sizes: 1g, 10g. Molecular Formula: C5H12N2O3, Molecular Weight: 148.16. US Biological Life Sciences. | Worldwide |
| Triazoledione | Triazoledione is a metabolite of Nefazodone, which could be used as an antidepressant for behaving as a SERT and NET inhibitor. Triazoledione has significant affinity for the serotonin 5-HT1A and 5-HT2A receptors, the α1-adrenergic receptor, and the histamine H1 receptor. Synonyms: BMS 180492; 1,2,4-Triazolidine-3,5-dione, 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-4-(2-phenoxyethyl)-; 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione. Grades: 98%. CAS No. 153707-88-1. Molecular formula: C23H28ClN5O3. Mole weight: 457.96. | |
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