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Nemadectin. Group: Biochemicals. Grades: Highly Purified. CAS No. 102130-84-7. Pack Sizes: 1mg. US Biological Life Sciences.
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Nemadectin
The dominant member of a class of milbemycins; shows pronounced nematocidal and insecticidal activity. Synonyms: CL-287088; S541A; LL-F28249 alpha. Grades: >95% by HPLC. CAS No. 102130-84-7. Molecular formula: C36H52O8. Mole weight: 612.79.
Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic. Group: Biochemicals. Alternative Names: Antibiotic S541A, Antibiotic LL-F28249 alpha. Grades: Highly Purified. CAS No. 102130-84-7. Pack Sizes: 1mg. US Biological Life Sciences.
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21-hydroxyoligomycin A (Nemadectin omega, Antibiotic LL-F28249 omega)
21-Hydroxyoligomycin A is a rare member of the oligomycin class isolated as a co-metabolite of nemadectin, hence its original naming as nemadectin omega. Only limited literature references to this metabolite are available. However, in-house testing suggests that 21-hydroxyoligomycin has a more selective action against mammalian tumor cell lines than oligomycin A, exhibiting only weak antifungal and nematocidal activity. Group: Biochemicals. Alternative Names: Nemadectin omega, Antibiotic LL-F28249 omega. Grades: Highly Purified. CAS No. 102042-09-1. Pack Sizes: 1mg. US Biological Life Sciences.
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23-Keto Nemadectin (Desmethoxyamino Moxidectin)
23-Keto Nemadectin (Desmethoxyamino Moxidectin) is a metabolite of Moxidectin, which is a parasiticide used for the prevention and control of heartworm and intestinal worms in veterinary medicine. Group: Biochemicals. Alternative Names: (6R,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-oxomilbemycin B; [6R,25S(E)]-5-O-Demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-oxo-milbemycin B; Spiro [11, 15-methano-2H, 13H, 17H-furo [4, 3, 2-pq] [2, 6] benzodioxa cyclooctadecin-13, 2'- [2H] pyran] Milbemycin B derivative. Grades: Highly Purified. CAS No. 112124-81-9. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O?, Molecular Weight: 610.78. US Biological Life Sciences.
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23-Keto O-Trimethylsilyl Nemadectin
23-Keto O-Trimethylsilyl Nemadectin is an intermediate in synthesizing Moxidectin-d3 (M744802), a the labelled form of Moxidectin (M744800). Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep. Group: Biochemicals. Grades: Highly Purified. CAS No. 112125-06-1. Pack Sizes: 500ug, 1mg. Molecular Formula: C42H64O8Si, Molecular Weight: 725.04. US Biological Life Sciences.
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21-Hydroxyoligomycin A
It is an anticancer antibiotic first isolated from S. cyaneogriseus ssp. noncyanogenus (LL-F28249). It has more selective action against mammalian tumour cell lines than Oligomycin A, exhibiting only weak antifungal and nematocidal activity. Synonyms: Nemadectin omega; LL-F28249 omega; (1R, 2'S, 4E, 5'S, 6S, 6'S, 7R, 8S, 10R, 11R, 12S, 14R, 15S, 16R, 18E, 20E, 22R, 25S, 28S, 29R)-22-Ethyl-3', 4', 5', 6'-tetrahydro-7, 11, 14, 15, 23-pentahydroxy-6'-[(2R)-2-hydroxypropyl]-5', 6, 8, 10, 12, 14, 16, 28, 29-nonamethylspiro[2, 26-dioxabicyclo[23.3.1]nonacosa-4, 18, 20-triene-27, 2'-[2H]pyran]-3, 9, 13-trione. Grades: >95% by HPLC. CAS No. 102042-09-1. Molecular formula: C45H74O12. Mole weight: 807.06.
Keto-Moxidectin
Keto-Moxidectin is a metabolite of Moxidectin, which is a parasiticide used for the prevention and control of heartworm and intestinal worms in veterinary medicine. Synonyms: 23-Keto Nemadectin; Desmethoxyamino Moxidectin; (6R,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-oxomilbemycin B; 23-Desmethoxyamino-23-oxo moxidectin; Moxidectin metabolite V (oxidation metabolite). CAS No. 112124-81-9. Molecular formula: C36H50O8. Mole weight: 610.78.
Milbemycin A3
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is the dominant member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels. Related to: Avermectin B1a, Avermectin B1b, Milbemycin A4, Milbemycin D, Nemadectin. Group: Biochemicals. Alternative Names: (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin B; Spiro [11, 15-methano-2H, 7H, 13H-furo [4, 3, 2-pq] [2, 6] benzodioxa cyclooctadecin-13, 2- [2H] pyran] , milbemycin B deriv.; (+)-Milbemycin α1; Antibiotic B 41A3; Emamectin A3; GWN 1725; Gowan 1725; Koromite; Matsuguard; Mesa; Mesa (acaricide); Milbeknock; Milbemectin; Milbemycin A3; Milbemycin α1; Ultiflora; Milbemycin EP Impurity B. Grades: Highly Purified. CAS No. 51596-10-2. Pack Sizes: 1mg. Molecular Formula: C??H??O?, Molecular Weight: 528.68. US Biological Life Sciences.
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Moxidectin
Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. It binds selectively to parasite. Group: Biochemicals. Grades: Highly Purified. CAS No. 113507-06-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
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