Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Nepicastat hydrochloride | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Nepicastat hydrochloride | Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine ( IC 50 =8.5 nM) and human ( IC 50 =9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SYN-117 hydrochloride; RS-25560-197 hydrochloride. CAS No. 170151-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13289A. |  |
| Nepicastat hydrochloride | Nepicastat hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Nepicastat HCl. Appearance: White to Beige Powder. CAS No. 170151-24-3. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. Purity: 0.95. Product ID: ACM170151243. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Nepicastat HCl | Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine/noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine/noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Synonyms: N6022; N 6022; N-6022; Nepicastat hydrochloride; (S)-5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1H-imidazole-2(3H)-thione hydrochloride; Nepicastat (hydrochloride); UNII-3WK068D17I. Grades: >98%. CAS No. 170151-24-3. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. |  |
| (R)-Nepicastat HCl | (R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter. Synonyms: RS-25560-198 HCl; RS 25560 198 HCl; (R)-5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1H-imidazole-2(3H)-thione hydrochloride. Grades: >98%. CAS No. 195881-94-8. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. | |
Our database is helping our users find suppliers everyday.
