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NESS 0327 NESS 0327 is a cannabinoid antagonist with high selectivity for the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 494844-07-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117139. MedChemExpress MCE
NESS 0327 NESS 0327 is a potent and selective cannabinoid (CB) receptor antagonist with selectivity for CB1 receptor over CB2 receptor with Ki values of 0.35 pM and 21 nM, respectively. It shows more potent efficacy for CB1 over SR 141716A. Synonyms: NESS 0327; 494844-07-4; NESS-0327; X1BQI2J97I; NESS0327; UNII-X1BQI2J97I; CHEMBL376700; Benzo(6,7)cyclohepta(1,2-C)pyrazole-3-carboxamide, 8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-; 8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-benzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide; N-(Piperidin-1-yl)-8-chloro-1-(2',4'-dichlorophenyl)-1,4,5,6-tetrahydrobenzo(6,7)cyclohepta(1,2-C)pyrazole-3-carboxamide. Grades: ≥98%. CAS No. 494844-07-4. Molecular formula: C24H23Cl3N4O. Mole weight: 489.8. BOC Sciences 10

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