Neuromedin Suppliers USA
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Product | Description | |
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Neuromedin B Quick inquiry Where to buy Suppliers range | Neuromedin B (NMB), an endogenous activator for the neuromedin B receptor (NMBR), is a member of Bombesin (BN)-like peptide family in mammals. Synonyms: H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2; glycyl-L-asparagyl-L-leucyl-L-tryptophyl-L-alanyl-L-threonyl-glycyl-L-histidyl-L-phenylalanyl-L-methioninamide; Neuromedin B (porcine); [125I]-Bolton Hunter neuromedin B; [125I]BH-NMB (human, mouse, rat). Grades: ≥95%. CAS No. 87096-84-2. Molecular formula: C52H73N15O12S. Mole weight: 1132.29. | |
Neuromedin B Quick inquiry Where to buy Suppliers range | Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals. Uses: Peptide Inhibitors. CAS No. 87096-84-2. Product ID: R1536. | |
Neuromedin C Quick inquiry Where to buy Suppliers range | Neuromedin C (NMC) is a decapeptide that acts as a growth factor in a variety of tumors. Synonyms: Neuromedin C (porcine); Gly-asn-his-trp-ala-val-gly-his-leu-met-NH2; GRP (18-27) (human, porcine, canine); Bombesin decapeptide; Grp-10; Gastrin releasing peptide 10; Canine gastrin-releasing peptide 10; Gastrin releasing peptide (18-27); glycyl-L-asparagyl-L-histidyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide. Grades: ≥95% by HPLC. CAS No. 81608-30-2. Molecular formula: C50H73N17O11S. Mole weight: 1120.29. | |
Neuromedin N Quick inquiry Where to buy Suppliers range | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Uses: Peptide Inhibitors. CAS No. 92169-45-4. Product ID: R1537. | |
Neuromedin N Quick inquiry Where to buy Suppliers range | Neuromedin N is an intricate peptide extensively investigated within the biomedical arena, offering profound insights into its multifaceted involvement in studying diverse neurological disorders. Acting upon distinct receptors both in the central nervous system and peripheral tissues, this product exhibits the potential to exert considerable impact on the modulation of neuronal activity. Synonyms: Neuromedin N; Lys-ile-pro-tyr-ile-leu; 102577-25-3; 92169-45-4; Lysyl-isoleucyl-prolyl-tyrosyl-isoleucyl-leucine; Neuromedin N (rat, mouse, porcine, canine); H-Lys-Ile-Pro-Tyr-Ile-Leu-OH; NmN-125; CHEMBL1558364; DTXSID20145280; HY-P0079; AKOS024456846; CS-5506; NCGC00167134-01; MS-31303; Q7002397; (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid; (S)-2-((2S,3S)-2-((S)-2-((S)-1-((2S,3S)-2-((S)-2,6-diaminohexanamido)-3-methylpentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid. Grades: 95%. CAS No. 102577-25-3. Molecular formula: C38H63N7O8. Mole weight: 745.9. | |
Neuromedin N acetate Quick inquiry Where to buy Suppliers range | Neuromedin N acetate is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. Synonyms: H-Lys-Ile-Pro-Tyr-Ile-Leu-OH.CH3CO2H; L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine acetic acid; Canine neuromedin N acetate salt; Mouse neuromedin N acetate salt; Neuromedin N (dog) acetate salt; Neuromedin N (human) acetate salt; Neuromedin N (ox) acetate salt; Neuromedin N (rat) acetate salt; Porcine neuromedin N acetate salt; Neuromedin N (rat, mouse, porcine, canine) acetate. Grades: ≥95%. Molecular formula: C40H67N7O10. Mole weight: 806.02. | |
Neuromedin S (human) Quick inquiry Where to buy Suppliers range | Neuromedin S (NMS), a 33-amino acid neuropeptide originally isolated from the rat brain, is a neuromedin U (NMU) receptor as an endogenous ligand of two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. NMS is involved in circadian rhythm regulation through autocrine and/or paracrine. Synonyms: NMS (human); H-Ile-Leu-Gln-Arg-Gly-Ser-Gly-Thr-Ala-Ala-Val-Asp-Phe-Thr-Lys-Lys-Asp-His-Thr-Ala-Thr-Trp-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; hNMS-33. Grades: ≥95%. CAS No. 1138204-27-9. Molecular formula: C173H265N53O44. Mole weight: 3791.34. | |
Neuromedin S (rat) Quick inquiry Where to buy Suppliers range | Neuromedin S, a novel neuropeptide of 36 amino acids isolated from rat brain as an endogenous ligand for the orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, is a potent, endogenous neuromedin U receptor agonist (EC50 values are 65 and 91 pM at NMU1 and NMU2 respectively). Central NMS may exert a physiological antidiuretic action via vasopressin release. Synonyms: L-leucyl-L-prolyl-L-arginyl-L-leucyl-L-leucyl-L-histidyl-L-threonyl-L-α-aspartyl-L-seryl-L-arginyl-L-methionyl-L-alanyl-L-threonyl-L-isoleucyl-L-α-aspartyl-L-phenylalanyl-L-prolyl-L-lysyl-L-lysyl-L-α-aspartyl-L-prolyl-L-threonyl-L-threonyl-L-seryl-L-leucylglycyl-L-arginyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide, trifluoroacetate salt; Leu-Pro-Arg-Leu-Leu-His-Thr-Asp-Ser-Arg-Met-Ala-Thr-Ile-Asp-Phe-Pro-Lys-Lys-Asp-Pro-Thr-Thr-Ser-Leu-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. CAS No. 843782-19-4. Molecular formula: C193H307N57O49S. Mole weight: 4241.97. | |
Neuromedin U-25 (human) Quick inquiry Where to buy Suppliers range | Neuromedin U-25 (NMU-25) is a 25-amino acid neuropeptide found in CNS of humans, demonstrated to drive smooth muscle contraction and regulate blood pressure. In vivo study has shown that it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. Synonyms: NMU-25 (human); H-Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-. Grades: ≥98%. CAS No. 312306-89-1. Molecular formula: C141H203N41O38. Mole weight: 3080.37. | |
Neuromedin U-25 porcine Quick inquiry Where to buy Suppliers range | Neuromedin U-25, from porcine spinal cord, is a potent stimulator of the smooth muscle of the rat uterus, and affects blood pressure in rats and dogs. Neuromedin U-8 is the same as Neuromedin U-25. Synonyms: Neuromedin u 25 (swinespinal cord); H-Phe-Lys-Val-Asp-Glu-Glu-Phe-Gln-Gly-Pro-Ile-Val-Ser-Gln-Asn-Arg-Arg-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-phenylalanyl-L-lysyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-phenylalanyl-L-glutaminyl-glycyl-L-prolyl-L-isoleucyl-L-valyl-L-seryl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; Neuromedin U-25 (porcine); NMU-25. Grades: ≥95%. CAS No. 98395-76-7. Molecular formula: C144H217N43O37. Mole weight: 3142.53. | |
Neuromedin (U8), porcine Quick inquiry Where to buy Suppliers range | Neuromedin (U8), porcine has potent agonist activity for neuromedin resceptors NMUR1 and NMUR2. Synonyms: Neuromedin U-8; L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; H-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. Grades: 95% by HPLC. CAS No. 98395-75-6. Molecular formula: C54H78N16O10. Mole weight: 1111.30. | |
Neuromedin U, rat Quick inquiry Where to buy Suppliers range | Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception. Uses: Peptide Inhibitors. CAS No. 117505-80-3. Product ID: R1538. | |
Neuromedin U, rat Quick inquiry Where to buy Suppliers range | Neuromedin U, a structurally highly conserved neuropeptide, is ubiquitously distributed, with highest levels found in the gastrointestinal tract and pituitary. Neuromedin U regulates blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function, and also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. Synonyms: Rat neuromedin U-23; H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-tyrosyl-L-lysyl-L-valyl-L-asparagyl-L-alpha-glutamyl-L-tyrosyl-L-glutaminyl-glycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-seryl-glycyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide. Grades: ≥95%. CAS No. 117505-80-3. Molecular formula: C124H180N34O31. Mole weight: 2642.97. | |
3-Chloro-2-fluorobenzaldehyde Quick inquiry Where to buy Suppliers range | 3-Chloro-2-fluorobenzaldehyde is an intermediate used to synthesize small-molecule inhibitors of MDM2-p53 interaction as antitumor agents. It is also used to prepare flavonoid derivatives as selective neuromedin U 2 receptor agonists for obesity treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 85070-48-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H4ClFO, Molecular Weight: 158.56. US Biological Life Sciences. | Worldwide |
(D-2-Nal5,Cys6 11,Tyr7,D-Trp8,Val10,2-Nal12)-Somatostatin-14 (5-12) amide Quick inquiry Where to buy Suppliers range | BIM 23042 is a selective neuromedin B receptor (NMB-R, BB1) antagonist (Ki = 216 and 18, 264 nM for BB1 and BB2 receptors, respectively) displaying no effect on a range of other receptors. Synonyms: H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2; BIM 23042. CAS No. 111857-96-6. Molecular formula: C62H73N11O9S2. Mole weight: 1180.44. | |
JMV 390-1 Quick inquiry Where to buy Suppliers range | JMV 390-1 inhibits multiple neurotensin and neuromedin N degrading enzymes. Uses: Peptide Inhibitors. CAS No. 148473-36-3. Product ID: R0908. | |
JMV 390-1 Quick inquiry Where to buy Suppliers range | JMV 390-1 has been found to be an inhibitor of the major neurotensin and neuromedin N degrading enzymes and could probably show analgesic activities. Synonyms: Jmv-390-1; Jmv390-1; N-[(2R)-4-Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-isoleucyl-L-leucine. Grades: ≥95% by HPLC. CAS No. 148473-36-3. Molecular formula: C23H35N3O6. Mole weight: 449.54. | |
JMV 449 Quick inquiry Where to buy Suppliers range | JMV 449 could be a neurotensin receptor agonist peptide and has been found to show hypothermic and analgesic activities in the mouse. Synonyms: JMV-449; JMV449; (S)-1-de-L-lysine-2-[N2-(2,6-diaminohexyl)-L-lysine]-neuromedin N (pig spinal cord); H-Lysy(CH2NH)Lys-Pro-Tyr-Ile-Leu-OH. Grades: ≥95% by HPLC. CAS No. 139026-66-7. Molecular formula: C38H66N8O7. Mole weight: 746.96. | |
Neurokinin A Quick inquiry Where to buy Suppliers range | Neurokinin A is a member of the endogenous tachykinin agonist with preference for the NK-2R (NK-2 receptor). Synonyms: Neurokinin A; Substance K; Neuromedin L; H-D-His-D-Lys-Thr-Asp-D-Ser-Phe-D-Val-Gly-D-Leu-D-Met-NH2. Grades: ≥97% by HPLC. CAS No. 86933-74-6. Molecular formula: C50H80N14O14S. Mole weight: 1133.33. | |
Neurokinin B Quick inquiry Where to buy Suppliers range | Neurokinin B, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Uses: Neurotransmitter agents. Synonyms: NKB; H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; Neurokinin K; Neurokinin beta; β-Neurokinin; Neuromedin K; (5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-4-yl)methyl)-32-amino-17,20-dibenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-14-isopropyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid. Grades: ≥95%. CAS No. 86933-75-7. Molecular formula: C55H79N13O14S2. Mole weight: 1210.42. | |
Neurokinin B acetate Quick inquiry Where to buy Suppliers range | Neurokinin B acetate, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Synonyms: H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2.CH3CO2H; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide acetic acid; Neurokinin B (swine spinal cord) acetate; Neurokinin B (human) acetate; Neurokinin B (pig spinal cord) acetate; Neurokinin B (porcine) acetate; Neurokinin β (pig spinal cord) acetate; Neuromedin K (pig spinal cord) acetate; Porcine neurokinin B acetate; Zneurok1 (human) acetate. Grades: ≥95%. Molecular formula: C57H83N13O16S2. Mole weight: 1270.48. | |
PD 168368 Quick inquiry Where to buy Suppliers range | PD 168368 is a competitive antagonist of neuromedin B (NMB) receptors. It blocks the elevation of intracellular calcium and release of inositol phosphate induced by NMB in cells expressing NMB receptors. Synonyms: (2S)-3-(1H-indol-3-yl)-2-methyl-2-[(4-nitrophenyl)carbamoylamino]-N-[(1-pyridin-2-ylcyclohexyl)methyl]propanamide. Grades: ≥95%. CAS No. 204066-82-0. Molecular formula: C31H34N6O4. Mole weight: 554.6. | |
PD 176252 Quick inquiry Where to buy Suppliers range | PD 176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively. PD 176252 inhibits proliferation of rat C6 glioma cells (IC50 = 2 μM) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC50 = 5 μM). Synonyms: (S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino]carbonyl]amino-1H-indole-3-propanamide; PD-176252; PD 176252; PD176252. Grades: ≥98% by HPLC. CAS No. 204067-01-6. Molecular formula: C32H36N6O5. Mole weight: 584.67. |