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| Product | Description | |
|---|---|---|
| Neuromedin B | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Neuromedin B | Neuromedin B (NMB), an endogenous activator for the neuromedin B receptor (NMBR), is a member of Bombesin (BN)-like peptide family in mammals. Synonyms: H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2; glycyl-L-asparagyl-L-leucyl-L-tryptophyl-L-alanyl-L-threonyl-glycyl-L-histidyl-L-phenylalanyl-L-methioninamide; Neuromedin B (porcine); [125I]-Bolton Hunter neuromedin B; [125I]BH-NMB (human, mouse, rat). Grade: ≥95%. CAS No. 87096-84-2. Molecular formula: C52H73N15O12S. Mole weight: 1132.29. |  |
| Neuromedin B | Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals. Uses: Scientific research. Group: Peptides. CAS No. 87096-84-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0241. |  |
| 4-10-Neuromedin b(swine spinal cord),N-(3-carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-(9ci) | 4-10-Neuromedin b(swine spinal cord),N-(3-carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: [SUCCINYL-ASP6,ME-PHE8] SUBSTANCE P;SUCCINYL-(ASP6,N-ME-PHE8)-SUBSTANCE P (6-11);[SUCCINYL-ASP6 N-ME-PHE8]-SUBSTANCE P (6-11) (SENKTIDE);[SUCCINYL-ASP6,N-ME-PHE8]-SUBSTANCE P, FRAGMENT 6-11;SUCCINYL-ASP-PHE-ME-PHE-GLY-LEU-MET-NH2;SUCCINYL-ASP-PHE-(N-ME)P. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 106128-89-6. Molecular formula: C40H55N7O11S. Mole weight: 841.97. Purity: 0.96. IUPACName: (3S)-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-[(4-hydroxy-4-oxobutanoyl)amino]-4-o. Density: 1.29 g/cm³. Product ID: ACM106128896. Alfa Chemistry ISO 9001:2015 Certified. Categories: Senktide trifluoroacetate salt. |  |
| 3-Chloro-2-fluorobenzaldehyde | 3-Chloro-2-fluorobenzaldehyde is an intermediate used to synthesize small-molecule inhibitors of MDM2-p53 interaction as antitumor agents. It is also used to prepare flavonoid derivatives as selective neuromedin U 2 receptor agonists for obesity treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 85070-48-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H4ClFO, Molecular Weight: 158.56. US Biological Life Sciences. |  Worldwide |
| BIM 23042 Acetate | BIM 23042 Acetate is a selective antagonist of neuromedin B. Molecular formula: C65H77N11O11S2. Mole weight: 1252.50. | |
| (D-2-Nal5,Cys6 11,Tyr7,D-Trp8,Val10,2-Nal12)-Somatostatin-14 (5-12) amide | BIM 23042 is a selective neuromedin B receptor (NMB-R, BB1) antagonist (Ki = 216 and 18, 264 nM for BB1 and BB2 receptors, respectively) displaying no effect on a range of other receptors. Synonyms: H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2; BIM 23042. CAS No. 111857-96-6. Molecular formula: C62H73N11O9S2. Mole weight: 1180.44. | |
| JMV 390-1 | JMV 390-1 has been found to be an inhibitor of the major neurotensin and neuromedin N degrading enzymes and could probably show analgesic activities. Synonyms: Jmv-390-1; Jmv390-1; N-[(2R)-4-Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-isoleucyl-L-leucine. Grade: ≥95% by HPLC. CAS No. 148473-36-3. Molecular formula: C23H35N3O6. Mole weight: 449.54. | |
| JMV 449 | JMV 449 could be a neurotensin receptor agonist peptide and has been found to show hypothermic and analgesic activities in the mouse. Synonyms: JMV-449; JMV449; (S)-1-de-L-lysine-2-[N2-(2,6-diaminohexyl)-L-lysine]-neuromedin N (pig spinal cord); H-Lysy(CH2NH)Lys-Pro-Tyr-Ile-Leu-OH. Grade: ≥95% by HPLC. CAS No. 139026-66-7. Molecular formula: C38H66N8O7. Mole weight: 746.96. | |
| Neurokinin A | Neurokinin A is a member of the endogenous tachykinin agonist with preference for the NK-2R (NK-2 receptor). Synonyms: Neurokinin A; Substance K; Neuromedin L; H-D-His-D-Lys-Thr-Asp-D-Ser-Phe-D-Val-Gly-D-Leu-D-Met-NH2. Grade: ≥97% by HPLC. CAS No. 86933-74-6. Molecular formula: C50H80N14O14S. Mole weight: 1133.33. | |
| Neurokinin b | Neurokinin b. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NEUROMEDIN K; NEUROKININ B; DMHDFFVGLM-NH2; NEUROKININ K; Neurokinin B NKB; NKB. Product Category: Heterocyclic Organic Compound. CAS No. 86933-75-7. Molecular formula: C55H79N13O14S2. Mole weight: 1210.42. Purity: 0.96. IUPACName: 3-amino-4-[[1-[[1-[[1-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-hydroxy-1,4-. Density: 1.313 g/cm³. Product ID: ACM86933757. Alfa Chemistry ISO 9001:2015 Certified. | |
| Neurokinin B | Neurokinin B, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Uses: Neurotransmitter agents. Synonyms: NKB; H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; Neurokinin K; Neurokinin beta; β-Neurokinin; Neuromedin K; (5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-4-yl)methyl)-32-amino-17,20-dibenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-14-isopropyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid. Grade: ≥95%. CAS No. 86933-75-7. Molecular formula: C55H79N13O14S2. Mole weight: 1210.42. | |
| Neurokinin B acetate | Neurokinin B acetate, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Synonyms: H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2.CH3CO2H; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide acetic acid; Neurokinin B (swine spinal cord) acetate; Neurokinin B (human) acetate; Neurokinin B (pig spinal cord) acetate; Neurokinin B (porcine) acetate; Neurokinin β (pig spinal cord) acetate; Neuromedin K (pig spinal cord) acetate; Porcine neurokinin B acetate; Zneurok1 (human) acetate. Grade: ≥95%. Molecular formula: C57H83N13O16S2. Mole weight: 1270.48. | |
| Neuromedin C | Neuromedin C (NMC) is a decapeptide that acts as a growth factor in a variety of tumors. Synonyms: Neuromedin C (porcine); Gly-asn-his-trp-ala-val-gly-his-leu-met-NH2; GRP (18-27) (human, porcine, canine); Bombesin decapeptide; Grp-10; Gastrin releasing peptide 10; Canine gastrin-releasing peptide 10; Gastrin releasing peptide (18-27); glycyl-L-asparagyl-L-histidyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide. Grade: ≥95% by HPLC. CAS No. 81608-30-2. Molecular formula: C50H73N17O11S. Mole weight: 1120.29. | |
| Neuromedin C (porcine) | Neuromedin C porcine (GRP, 18-27, porcine) is a bombesin-like neuropeptide that can be obtained from porcine spinal cord. Neuromedin C porcine exhibits a potent contractile activity on rat uterus in the characteristic manner of bombesin. Neuromedin C porcine has research potential for neurological-related diseases [1]. Uses: Scientific research. Group: Peptides. Alternative Names: GRP(18-27) (porcine). CAS No. 81608-30-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103283. | |
| Neuromedin N | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Uses: Scientific research. Group: Peptides. Alternative Names: Neuromedin N (rat, mouse, porcine, canine). CAS No. 92169-45-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0079. | |
| Neuromedin N acetate | Neuromedin N acetate is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. Synonyms: H-Lys-Ile-Pro-Tyr-Ile-Leu-OH.CH3CO2H; L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine acetic acid; Canine neuromedin N acetate salt; Mouse neuromedin N acetate salt; Neuromedin N (dog) acetate salt; Neuromedin N (human) acetate salt; Neuromedin N (ox) acetate salt; Neuromedin N (rat) acetate salt; Porcine neuromedin N acetate salt; Neuromedin N (rat, mouse, porcine, canine) acetate. Grade: ≥95%. Molecular formula: C40H67N7O10. Mole weight: 806.02. | |
| Neuromedin N (swine spinal cord) | Neuromedin N is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. It produced a significant concentration-related increase in the Kd values of [3H]L-(-)-N-propylnorapomorphine binding sites in the concentration range of 1-10 nM. It is endogenous neurotensin-like neuropeptide isolated from porcine spinal cord. It binds to neurotensin receptors. It regulates guinea pig intestinal smooth muscle contraction and produces hypotension in rats. It also induces hypothermia following central administration in rats in vivo. Synonyms: L-Leucine, L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-; L-Lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; Neuromedin N (pig spinal cord); Canine neuromedin N; Mouse neuromedin N; Neuromedin N (dog); Neuromedin N (human); Neuromedin N (ox); Neuromedin N (rat); Porcine neuromedin N; Neuromedin N (rat, mouse, porcine, canine); H-Lys-Ile-Pro-Tyr-Ile-Leu-OH; L-Lys-L-Ile-L-Pro-L-Tyr-L-Ile-L-Leu-OH; Lysyl-isoleucyl-prolyl-tyrosyl-isoleucyl-leucine. Grade: >98%. CAS No. 92169-45-4. Molecular formula: C38H63N7O8. Mole weight: 745.95. | |
| Neuromedin S (human) | Neuromedin S (NMS), a 33-amino acid neuropeptide originally isolated from the rat brain, is a neuromedin U (NMU) receptor as an endogenous ligand of two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. NMS is involved in circadian rhythm regulation through autocrine and/or paracrine. Synonyms: NMS (human); H-Ile-Leu-Gln-Arg-Gly-Ser-Gly-Thr-Ala-Ala-Val-Asp-Phe-Thr-Lys-Lys-Asp-His-Thr-Ala-Thr-Trp-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; hNMS-33. Grade: ≥95%. CAS No. 1138204-27-9. Molecular formula: C173H265N53O44. Mole weight: 3791.34. | |
| Neuromedin U-25 (human) | Neuromedin U-25 (NMU-25) is a 25-amino acid neuropeptide found in CNS of humans, demonstrated to drive smooth muscle contraction and regulate blood pressure. In vivo study has shown that it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. Synonyms: NMU-25 (human); H-Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-. Grade: ≥98%. CAS No. 312306-89-1. Molecular formula: C141H203N41O38. Mole weight: 3080.37. | |
| Neuromedin U-25 porcine | Neuromedin U-25, from porcine spinal cord, is a potent stimulator of the smooth muscle of the rat uterus, and affects blood pressure in rats and dogs. Neuromedin U-8 is the same as Neuromedin U-25. Synonyms: Neuromedin u 25 (swinespinal cord); H-Phe-Lys-Val-Asp-Glu-Glu-Phe-Gln-Gly-Pro-Ile-Val-Ser-Gln-Asn-Arg-Arg-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-phenylalanyl-L-lysyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-phenylalanyl-L-glutaminyl-glycyl-L-prolyl-L-isoleucyl-L-valyl-L-seryl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; Neuromedin U-25 (porcine); NMU-25. Grade: ≥95%. CAS No. 98395-76-7. Molecular formula: C144H217N43O37. Mole weight: 3142.53. | |
| Neuromedin (U8), porcine | Neuromedin (U8), porcine has potent agonist activity for neuromedin resceptors NMUR1 and NMUR2. Synonyms: Neuromedin U-8; L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; H-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. Grade: 95% by HPLC. CAS No. 98395-75-6. Molecular formula: C54H78N16O10. Mole weight: 1111.30. | |
| Neuromedin U, rat | Neuromedin U, a structurally highly conserved neuropeptide, is ubiquitously distributed, with highest levels found in the gastrointestinal tract and pituitary. Neuromedin U regulates blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function, and also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. Synonyms: Rat neuromedin U-23; H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-tyrosyl-L-lysyl-L-valyl-L-asparagyl-L-alpha-glutamyl-L-tyrosyl-L-glutaminyl-glycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-seryl-glycyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide. Grade: ≥95%. CAS No. 117505-80-3. Molecular formula: C124H180N34O31. Mole weight: 2642.97. | |
| PD176252 | PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 ?M in HL-60 cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 204067-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103286. | |
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