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| Product | Description | |
|---|---|---|
| Neuropeptide FF | Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: NPFF. CAS No. 99566-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1248. |  |
| Neuropeptide FF | Neuropeptide FF, which belongs to the RF-amide family of peptides, is an endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki= 2.82 and 0.21 nM respectively). Neuropeptide FF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol. Uses: Narcotic antagonists. Synonyms: NPFF; H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2; L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide. Grades: ≥95% by HPLC. CAS No. 99566-27-5. Molecular formula: C54H76N14O10. Mole weight: 1081.27. |  |
| Anti-Neuropeptide FF1 Receptor (NPFF1) antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| BIBP 3226 | BIBP 3226 is a mixed non-peptide neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Ki = 1.1, 79, 108, >1000, >1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4 and rNPY Y5, respectively). It exhibits an anxiogenic-like effect in rats following i.c.v. administration. Synonyms: BIBP3226; BIBP-3226; N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-arginine amide; (R)-2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamide; N5-(Diaminomethylene)-N2-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-D-ornithinamide; N-[ (1R) ]-4-[ (Aminoiminomethyl) amino-1-[[[ (4-hydroxyphenyl) methyl]amino]carbonyl]butyl-α -phenylbenzeneacetamide; Diphenylacetyl-D-Arg-4-hydroxybenzylamide. Grades: ≥98%. CAS No. 159013-54-4. Molecular formula: C27H31N5O3. Mole weight: 473.57. | |
| BIBP 3226 TFA | BIBP 3226 trifluoroacetate is a mixed non-peptide neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Ki = 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4 and rNPY Y5, respectively). BIBP 3226 exhibits an anxiogenic-like effect in rats following i.c.v. administration. Synonyms: BIBP 3226 trifluoroacetate; BIBP3226 trifluoroacetate; BIBP-3226 trifluoroacetate; N-[ (1R) ]-4-[ (Aminoiminomethyl) amino-1-[[[ (4-hydroxyphenyl) methyl]amino]carbonyl]butyl-α -phenylbenzeneacetamide trifluoroacetate; N5-(Diaminomethylene)-N2-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-D-ornithinamide trifluoroacetate; Diphenylacetyl-D-Arg-4-hydroxybenzylamide trifluoroacetate. Grades: ≥98% by HPLC. CAS No. 1068148-47-9. Molecular formula: C27H31N5O3.C2HF3O2. Mole weight: 587.59. | |
| BIBP3226 TFA | BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with K i s of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1068148-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107726. | |
| Neuropeptide SF (mouse, rat) | Neuropeptide SF (mouse, rat) is a neuropeptide FF receptor agonist (Ki= 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH. Synonyms: Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2. CAS No. 230960-31-3. Molecular formula: C40H65N13O10. Mole weight: 888.03. | |
| Neuropeptide SF (mouse, rat) acetate | Neuropeptide SF (mouse, rat) acetate is a neuropeptide FF receptor agonist (Ki = 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH. Synonyms: H-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid. Grades: ≥95%. CAS No. 2760881-61-4. Molecular formula: C42H69N13O12. Mole weight: 948.08. | |
| Prolactin Releasing Peptide (1-31), human | Prolactin releasing peptide (PrRP) is a 31-amino acid neuropeptide encoded by the PRLH gene. It acts as an agonist of the G-protein coupled receptors GPR10/hGR3 and neuropeptide FF receptor (hNPFF2). Synonyms: PrRP-31, human; Human PrRP-31; Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2; L-seryl-L-arginyl-L-threonyl-L-histidyl-L-arginyl-L-histidyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-isoleucyl-L-arginyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-isoleucyl-L-asparagyl-L-prolyl-L-alanyl-L-tryptophyl-L-tyrosyl-L-alanyl-L-seryl-L-arginyl-glycyl-L-isoleucyl-L-arginyl-L-prolyl-L-valyl-glycyl-L-arginyl-L-phenylalaninamide; [125I]-PrRP31. Grades: ≥95%. CAS No. 215510-22-8. Molecular formula: C160H252N56O42S. Mole weight: 3664.15. | |
| RF9 | RF9 is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 876310-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107382. | |
| RF 9 | RF 9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively. It displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Synonyms: 2-Adamantanecarbonyl-Arg-Phe-NH2. Grades: ≥96%. CAS No. 876310-60-0. Molecular formula: C26H38N6O3. Mole weight: 482.62. | |
| RFRP-1(human) | RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428. | |
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