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| Product | Description | |
|---|---|---|
| Neuropeptide S (mouse) | Neuropeptide S (mouse) is a bioactive peptide. Neuropeptide S (mouse), as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behaviors, memory and agent addiction [1]. Uses: Scientific research. Group: Peptides. CAS No. 412938-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1437. |  |
| Neuropeptide S (Mouse) | Neuropeptide S, a 20 amino acid modulatory neuropeptide, is a potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). Previous studies in rat and mouse showed that NPS is expressed by a few well-defined pontine neuronal clusters that project to several distinct rostral forebrain areas, including the septum, hypothalamus and thalamus. Its G-protein-coupled receptor, NPSR1, is however widely distributed throughout the brain and mediates predominantly excitatory signals. In agreement, the NPS neurons are glutamatergic. Synonyms: H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH. CAS No. 412938-74-0. Molecular formula: C93H156N34O27. Mole weight: 2182.47. |  |
| Neuropeptide S (Mouse) acetate | Neuropeptide S (Mouse) acetate, a 20 amino acid modulatory neuropeptide, is a potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). It can be used for the research of arousal, anxiety, locomotion, feeding behaviors, memory, and drug addiction. Synonyms: 1-20-Protein (mouse TGR23-2 ligand) acetate; L-Seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-serylglycyl-L-alanyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-arginyl-L-arginyl-L-alanyl-L-lysyl-L-glutamine acetate; H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C95H160N34O29. Mole weight: 2242.53. | |
| Neuropeptide SF (mouse, rat) | Neuropeptide SF (mouse, rat) is a neuropeptide FF receptor agonist (Ki= 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH. Synonyms: Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2. CAS No. 230960-31-3. Molecular formula: C40H65N13O10. Mole weight: 888.03. | |
| Neuropeptide SF (mouse, rat) acetate | Neuropeptide SF (mouse, rat) acetate is a neuropeptide FF receptor agonist (Ki = 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH. Synonyms: H-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid. Grade: ≥95%. CAS No. 2760881-61-4. Molecular formula: C42H69N13O12. Mole weight: 948.08. | |
| Neuropeptide Y (human,rat,mouse) | Neuropeptide Y (human,rat,mouse) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide Y (29-64), amide. CAS No. 90880-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0198. | |
| α-CGRP (mouse, rat) | ?-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. ?-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. ?-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies[1][2][3][4]. Uses: Scientific research. Group: Peptides. Alternative Names: CGRP (83-119), mouse, rat. CAS No. 83651-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0203. | |
| Apelin-13 | Apelin-13, an endogenous neuropeptide, is the ligand for the G-protein-coupled receptor APJ, an alternative coreceptor with CD4 for HIV-1 infection. Apelin-13 is generated from apelin-36, which is a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with EC50 value of 0.37 nM. Apelin-13 is a 13 amino acid polypeptide encoded by the apelin gene which yields a pre-proprotein that is processed to generate bioactive peptides. Apelin-13 is also involved in the learning and memory process. Synonyms: Apelin-13 (human, bovine, mouse, rat); H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH; L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine. Grade: ≥95%. CAS No. 217082-58-1. Molecular formula: C69H111N23O16S. Mole weight: 1550.85. | |
| β-Endorphin (bovine, camel, mouse) | β-Endorphin is an endogenous opioid neuropeptide. Uses: Neurotransmitter agents. Synonyms: beta-Endorphin (bovine, camel, mouse); beta-Endorphin (1-31); H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln-OH. Grade: ≥98%. CAS No. 59887-17-1. Molecular formula: C155H250N42O44S. Mole weight: 3437.96. | |
| BigLEN (mouse) | BigLEN (mouse) is a proSAAS-derived neuropeptide that acts as a GPR171 agonist. It regulates food intake in mice, and suppresses the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. CAS No. 501036-69-7. Molecular formula: C78H130N24O22. Mole weight: 1756.03. | |
| BigLEN (mouse) acetate | BigLEN (mouse) acetate is a proSAAS-derived neuropeptide that acts as a GPR171 agonist. It regulates food intake in mice, and suppresses the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. Molecular formula: C80H134N24O24. Mole weight: 1816.07. | |
| Galanin (rat, mouse) trifluoroacetate salt | Galanin is a 29 amino acid, C-terminally amidated neuropeptide with diverse biological activities. Galanin binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62, and 12.3 nM, respectively). Synonyms: GAL (rat, mouse); Galanin (1-29) (rat, mouse). Grade: ≥95%. Molecular formula: C141H211N43O41·xCF3COOH. Mole weight: 3164.45. | |
| Neuromedin N (swine spinal cord) | Neuromedin N is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. It produced a significant concentration-related increase in the Kd values of [3H]L-(-)-N-propylnorapomorphine binding sites in the concentration range of 1-10 nM. It is endogenous neurotensin-like neuropeptide isolated from porcine spinal cord. It binds to neurotensin receptors. It regulates guinea pig intestinal smooth muscle contraction and produces hypotension in rats. It also induces hypothermia following central administration in rats in vivo. Synonyms: L-Leucine, L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-; L-Lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; Neuromedin N (pig spinal cord); Canine neuromedin N; Mouse neuromedin N; Neuromedin N (dog); Neuromedin N (human); Neuromedin N (ox); Neuromedin N (rat); Porcine neuromedin N; Neuromedin N (rat, mouse, porcine, canine); H-Lys-Ile-Pro-Tyr-Ile-Leu-OH; L-Lys-L-Ile-L-Pro-L-Tyr-L-Ile-L-Leu-OH; Lysyl-isoleucyl-prolyl-tyrosyl-isoleucyl-leucine. Grade: >98%. CAS No. 92169-45-4. Molecular formula: C38H63N7O8. Mole weight: 745.95. | |
| Neuropeptide EI, rat | Neuropeptide EI, rat exhibits functional melanin-concentrating hormone (MCH) antagonist and melanocyte-stimulating hormone (MSH) agonist activities under different behavioral patterns. Synonyms: Neuropeptide EI (human, mouse, rat); H-Glu-Ile-Gly-Asp-Glu-Glu-Asn-Ser-Ala-Lys-Phe-Pro-Ile-NH2; L-alpha-glutamyl-L-isoleucyl-glycyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-asparagyl-L-seryl-L-alanyl-L-lysyl-L-phenylalanyl-L-prolyl-L-isoleucinamide; NEI (rat). Grade: ≥95%. CAS No. 125934-45-4. Molecular formula: C63H98N16O23. Mole weight: 1447.55. | |
| Orexin A (16-33) | Orexin A (16-33) lacks the disulfide bridge of orexin A, but retains part of the full-length OXA/OXB activity. It has been used in place of intact neuropeptides. Synonyms: Hypocretin-1 (16-33) (Human, Mouse Rat); H-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2; L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-histidyl-glycyl-L-alanyl-glycyl-L-asparagyl-L-histidyl-L-alanyl-L-alanyl-glycyl-L-isoleucyl-L-leucyl-L-threonyl-L-leucinamide; OXA 16-33. Grade: ≥95%. CAS No. 1374694-00-4. Molecular formula: C85H136N24O23. Mole weight: 1862.16. | |
| Orexin A (human, rat, mouse) | Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor ( OX1R ) and the orexin-2 receptor ( OX2R ). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Hypocretin-1 (human, rat, mouse). CAS No. 205640-90-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106224. | |
| Orexin A (human, rat, mouse) acetate | Orexin A (Hypocretin-1) (human, rat, mouse) acetate is a hypothalamic neuropeptide with analgesic properties (crosses the blood-brain barrier). Orexin A (human, rat, mouse) acetate binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) acetate can be used in studies of appetite regulation, neurodegenerative diseases and modulation of injurious messaging[1][2][3][4]. Uses: Scientific research. Group: Peptides. Alternative Names: Hypocretin-1 (human, rat, mouse) acetate. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106224B. | |
| PACAP-38 (human, mouse, ovine, porcine, rat) | PACAP-38 (human, mouse, ovine, porcine, rat) is a multifunctional neuropeptide that interacts with PACAP receptors and vasoactive intestinal peptide receptors to enhance intracellular cyclic AMP levels and exert systemic effects. It is a PAC1 agonist that strongly increases α-secretase activity. Upregulation of the APP-degrading enzyme promotes non-amyloidogenic processing of APP by reducing Aβ40/42 production, and thus may contribute to the prevention of Alzheimer's disease. Intranasal application of PACAP-38 in APP[V717I]-transgenic mice promotes the production of Aβ-degrading enzyme neprilysin by inducing somatostatin. Synonyms: Pituitary Adenylate Cyclase Activating Polypeptide-38 (human, mouse, ovine, porcine, rat); H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-glycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-arginyl-L-tyrosyl-L-lysyl-L-glutaminyl-L-arginyl-L-valyl-L-lysyl-L-asparagyl-L-lysinamide. Grade: 95%. CAS No. 124123-15-5. Molecular formula: C203H331N63O53S. Mole weight: 4534.32. | |
| Peptide YY (3-36) | Peptide YY (3-36) is a Y2/Y5 Neuropeptide Y receptor agonist (IC50= 0.11 nM for inhibition of 125I-PYY binding to Y2 receptor). Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. Synonyms: Peptide YY (PYY) (3-36), human; H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2; L-alanyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-seryl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-leucyl-L-asparagyl-L-leucyl-L-valyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide; PYY (3-36) (canine, mouse, porcine, rat). Grade: 98%. CAS No. 126339-09-1. Molecular formula: C176H272N52O54. Mole weight: 3980.42. | |
| (R)-JNJ-31020028 | (R)-JNJ-31020028 is a high affinity, selective brain penetrant antagonist of neuropeptide Y Y2 receptor (pIC50 values of 8.07, 8.22 and 8.21 for human, rat, and mouse Y2 receptor, respectively). Synonyms: (R)-N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide. CAS No. 1094873-17-2. Molecular formula: C34H36FN5O2. Mole weight: 565.68. | |
| Secretoneurin, rat | Secretoneurin, rat, a 33-amino acid polypeptide, is a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). The endogenous peptide can enhance dopamine release. Synonyms: Secretoneurin (mouse)(9CI); H-THR-ASN-GLU-ILE-VAL-GLU-GLU-GLN-TYR-THR-PRO-GLN-SER-LEU-ALA-THR-LEU-GLU-SER-VAL-PHE-GLN-GLU-LEU-GLY-LYS-LEU-THR-GLY-PRO-SER-ASN-GLN-OH. Grade: >95%. CAS No. 149146-12-3. Molecular formula: C159H252N40O58. Mole weight: 3651.94. | |
| Secretoneurin, rat acetate | Secretoneurin, rat acetate, a 33-amino acid polypeptide, is a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). The endogenous peptide can enhance dopamine release. Synonyms: L-Threonyl-L-asparaginyl-L-α-glutamyl-L-isoleucyl-L-valyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-tyrosyl-L-threonyl-L-prolyl-L-glutaminyl-L-seryl-L-leucyl-L-alanyl-L-threonyl-L-leucyl-L-α-glutamyl-L-seryl-L-valyl-L-phenylalanyl-L-glutaminyl-L-α-glutamyl-L-leucylglycyl-L-lysyl-L-leucyl-L-threonylglycyl-L-prolyl-L-seryl-L-asparaginyl-L-glutamine acetate; Secretoneurin (mouse) acetate; H-Thr-Asn-Glu-Ile-Val-Glu-Glu-Gln-Tyr-Thr-Pro-Gln-Ser-Leu-Ala-Thr-Leu-Glu-Ser-Val-Phe-Gln-Glu-Leu-Gly-Lys-Leu-Thr-Gly-Pro-Asn-Ser-Gln-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C161H256N40O60. Mole weight: 3712.04. | |
| Spexin | Spexin is an endogenous satiety-inducing peptide and a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 = 45.7 and 112.2 nM, respectively), displaying no significant activity at galanin receptor 1. Spexin inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. It exhibits anxiolytic effects in vivo. Synonyms: SPX; NPQ (human, mouse, bovine); H-Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2; L-asparagyl-L-tryptophyl-L-threonyl-L-prolyl-L-glutaminyl-L-alanyl-L-methionyl-L-leucyl-L-tyrosyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-glutaminamide; Neuropeptide Q; Spexin (36-49) amidated. Grade: ≥95%. CAS No. 1370290-58-6. Molecular formula: C74H114N20O19S. Mole weight: 1619.91. | |
| Urocortin III, mouse | Urocortin III a neuropeptide hormone and a member of the corticotropin-releasing factor (CRF) family, is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Synonyms: STRESSCOPIN (3-40) (MOUSE). CAS No. 357952-10-4. Molecular formula: C186H312N52O52S2. Mole weight: 4172.97. | |
| Cortistatin 14 (mouse, rat) | Cortistatin-14 is an endogenous neuropeptide expressed in the cortex and hippocampus. Synonyms: Cortistatin-14; H-PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH; CST-14; CST-14 (RAT). Grade: 98%. CAS No. 186901-48-4. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01. | |
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