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| Product | Description | |
|---|---|---|
| Neutral Protease AF GMP Grade | Neutral Protease AF GMP Grade is manufactured according to cGMP guidelines using a production process completely free of animal-based components. In this way the introduction of any potential animal-derived pathogen is excluded. Neutral Protease AF GMP Grade is chromatographically purified and largely free from collagenolytic activity (PZ U) as well as endotoxins. The absence of any animal-derived ingredients and thorough microbial analysis provide the highest possible safety. Applications: Neutral protease af gmp grade is suitable for cell isolation from several tissue types for clinical applications. it is often used in combination with collagenase af-1 gmp grade. Group: Enzymes. Synonyms: Neutral Protease AF GMP Grade; Neutral Protease AF; Neutral Protease; Protease. Enzyme Commission Number: EC 3.4.21.62. CAS No. 9001-92-7. Protease. Mole weight: 34 000. Activity: ≥ 0.50 U/mg. Storage: 2 to 8 °C. Form: Lyophilized powder. Source: Clostridium histolyticum. Neutral Protease AF GMP Grade; Neutral Protease AF; Neutral Protease; Protease. Cat No: NATE-1920. |  |
| Neutral Protease for Beer Brewing (Food Grade) | Neutral Protease is made from Bacillus subtilis No. 1.398 through fermentation and extraction technique. This product can catalyze protein to hydrolyze into low molecular peptide and amino acid. It is mainly used in the industry of Beer Brewing. Applications: Enzyme in beer brewing. Group: Enzymes. Synonyms: Neutral Protease; Beer Brewing; Enzyme in Beer Brewing; Protease. CAS No. 9001-92-7. Neutral Protease. Activity: 70000u/g. Storage: Should be stored in a cool place avoiding high temperature. Powder: 12 months at 25°C, activity remain >90%. Increase dosage after shelf life. Form: Powder. Source: Bacillus subtilis. Neutral Protease; Beer Brewing; Enzyme in Beer Brewing; Protease. Pack: 25kgs/bag, 1.125kgs/bag. Cat No: BER-001. | |
| Neutral Protease for pet food | An enzyme capable of hydrolyzing protein to peptides and amino acids. Typically used in pet food and flavor manufacture. Applications: Baking , dietary ,supplements, food & beverage. Group: Enzymes. Synonyms: Neutral Protease; Neutral Protease for pet food; Baking Enzymes; BAK-1730. CAS No. 9001-92-7. Neutral Protease. Appearance: powder or liquid. Neutral Protease; Neutral Protease for pet food; Baking Enzymes; BAK-1730. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: BAK-1730. | |
| Neutral protease I | Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dispase I. CAS No. 42613-33-2. Pack Sizes: 1 mg. Product ID: HY-131577A. |  |
| Collagenase/Neutral Protease Blend (GMP Grade) | NATE-1917 is an avian and mammalian tissue-free Collagenase and neutral protease enzyme blend produced under GMP quality conditions. Applications: Nate-1917 is specifically designed for stem cell isolation from human and other adipose tissue with following advantages:o a single, sterile, ready-to-use vial containing both collagenase and neutral protease can digest up to 280g of adipose tissue with best-in-class gmp quality and shelf life of up to 72 months.o currently included in ide applications approved by the u.s. fda for alopecia, chronic heart failure, hamstring injuries, osteoarthritis of the knee, and hand manifestations of scleroderma.o research protocols are a...sociation of nucleated cells from adipose tissue.o produced using avian and mammalian tissue-free raw materials, aseptic processes and sterile filtration under gmp guidelines to assure the lowest levels of impurities and stringent quality standards. Group: Enzymes. Synonyms: Collagenase/Neutral Protease Blend; GMP, Collagenase/Neutral Protease Blend; Collagenase; Neutral Protease; GMP. Collagenase. Stability: 48 months at -15 to -25° C. Appearance: White lyophilizate. Source: Clostridium histolyticum/Bacillus polymyxa. Collagenase/Neutral Protease Blend; GMP, Collagenase/Neutral Protease Blend; Collagenase; Neutral Protease; GMP. Pack: 1 vial, 35 mg. Cat No: NATE-1917. | |
| Concentrated neutral bacterial protease for detergent | Highly concentrated neutral bacterial protease enzyme used in laundry detergents and cleaning products to remove protein containing stains such as grass, blood, mucus, feces and foods. Applications: Protein stains. Group: Enzymes. Synonyms: Concentrated neutral bacterial protease; for detergent; concentrated neutral bacterial protease enzyme; laundry detergents; remove protein containing stains?Detergent Enzymes; bacterial protease; neutral protease; Detergents; Concentrated neutral bacterial protease for detergent; DETE-2626. CAS No. 37259-58-8. Neutral Protease. Appearance: powder or liquid. Source: Bacterial. Concentrated neutral bacterial protease; for detergent; concentrated neutral bacterial protease enzyme; laundry detergents; remove protein containing stains?Detergent Enzymes; bacterial protease; neutral protease; Detergents; Concentrated neutral bacterial protease for detergent; DETE-2626. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2626. | |
| Native Bacillus polymyxa Neutral Protease (Dispase) | Neutral protease (Dispase) is a non-mammalian animal origin free (AOF) metallo, neutral protease. Its mild proteolytic action makes the enzyme especially suitable for the preparation of primary cells and secondary (subcultivation) cell culture, since it is gentle on cell membranes. This protease is also used as a secondary enzyme in cell isolation and tissue dissociation applications, commonly used with collagense. Chromatographically purified. a lyophilized powder. Applications: Tissue disaggregation and subcultivation; prevention of unwanted cell clumping; preparation of cells for culture; separation of intact epidermis from dermis and intact epithelial sheet in c...se; Neutral Protease (Dispase). Enzyme Commission Number: EC 3.4.24.28. CAS No. 9001-92-7. Purity: Chromatographically purified. Neutral Protease. Mole weight: 32.5 kDa. Activity: > 4 units per mg dry weight. Stability: Stable at 2-8°C for 12 months. Aliquot and Store at -20°C after reconstitution with water or commonly used balanced salt solutions or media. Storage: Store at 2-8°C. Form: lyophilized powder. Source: Bacillus polymyxa. Bacillolysin; EC 3.4.24.28; Bacillus metalloendopeptidase; Bacillus subtilis neutral proteinase; anilozyme P 10; Bacillus metalloproteinase; Bacillus neutral proteinase; megateriopeptidase; Neutral Protease (Dispase). Cat No: NATE-0482. | |
| Neutral/alkaline protease for meat proteins | Concentrated neutral - alkaline pH protease enzyme used to hydrolyze protein into smaller polypeptides and free amino acids. It is often combined with a neutral to acid pH protease for more complete processing. Applications: Meat & fish proteins. Group: Enzymes. Neutral/alkaline protease. Appearance: powder or liquid. protease; Neutral - alkaline protease; for meat proteins; Meat and Fish Proteins; neutral - alkaline protease enzyme; alkaline protease; Neutral protease; PRO-1823. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: PRO-1823. | |
| Neutral/alkaline protease for vegetable proteins | A concentrated, neutral - alkaline pH protease enzyme used as a processing aid in technical applications to break down protein and increase their solubility, dispersability and digestibility. Applications: Vegetable proteins. Group: Enzymes. Neutral/alkaline protease. Appearance: powder or liquid. protease; Neutral - alkaline protease; for meat proteins; Meat and Fish Proteins; neutral - alkaline protease enzyme; alkaline protease; Neutral protease; PRO-1823. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: PRO-1824. | |
| Neutral bacterial protease for detergent | Neutral bacterial protease enzyme used in laundry detergents and cleaning products to remove protein-containing stains such as grass, blood, mucus, feces and foods. Applications: Protein stains. Group: Enzymes. Synonyms: Neutral bacterial protease; for detergent; neutral bacterial protease enzyme; laundry detergents; remove protein-containing stains; Detergent Enzymes; bacterial protease; Detergents; Neutral bacterial protease for detergent; DETE-2625. CAS No. 37259-58-8. Neutral Protease. Appearance: powder or liquid. Source: Bacterial. Neutral bacterial protease; for detergent; neutral bacterial protease enzyme; laundry detergents; remove protein-containing stains; Detergent Enzymes; bacterial protease; Detergents; Neutral bacterial protease for detergent; DETE-2625. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2625. | |
| Aminopeptidase N Inhibitor | Membrane alanyl aminopeptidase is also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N), which is an enzyme that in humans is encoded by the ANPEP gene. Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. Synonyms: AP-N Inhibitor. Grades: ≥95%. CAS No. 596108-59-7. Molecular formula: C17H10N2O8. Mole weight: 370.27. |  |
| aureolysin | A metalloenzyme from S. aureus earlier confused with staphylokinase (a non-enzymic activator of plasminogen). Group: Enzymes. Synonyms: Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Enzyme Commission Number: EC 3.4.24.29. CAS No. 39335-13-2. Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4310; aureolysin; EC 3.4.24.29; 39335-13-2; Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Cat No: EXWM-4310. | |
| bacillolysin | Variants of this enzyme have been found in species of Bacillus including B. subtilis, B. amyloliquefaciens, B. megaterium (megateriopeptidase,), B. mesentericus, B. cereus and B. stearothermophilus. In peptidase family M4 (thermolysin family). Formerly included in EC 3.4.24.4. Group: Enzymes. Synonyms: Bacillus metalloendopeptidase; Bacillus subtilis neutral proteinase; anilozyme P 10; Bacillus metalloproteinase; Bacillus neutral proteinase; megateriopeptidase. Enzyme Commission Number: EC 3.4.24.28. CAS No. 9080-56-2. Neutral Protease. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4309; bacillolysin; EC 3.4.24.28; 9080-56-2; Bacillus metalloendopeptidase; Bacillus subtilis neutral proteinase; anilozyme P 10; Bacillus metalloproteinase; Bacillus neutral proteinase; megateriopeptidase. Cat No: EXWM-4309. | |
| calpain-1 | In peptidase family C2. Requires Ca2+ at micromolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.53, calpain-2. Group: Enzymes. Synonyms: μ-calpain; calcium-activated neutral protease I. Enzyme Commission Number: EC 3.4.22.52. CAS No. 78990-62-2. Calpain 1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4227; calpain-1; EC 3.4.22.52; 78990-62-2; μ-calpain; calcium-activated neutral protease I. Cat No: EXWM-4227. | |
| calpain-2 | Type example of peptidase family C2. Requires Ca2+ at millimolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.52, calpain-1. Group: Enzymes. Synonyms: calcium-activated neutral protease II; m-calpain; milli-calpain. Enzyme Commission Number: EC 3.4.22.53. CAS No. 702693-80-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4228; calpain-2; EC 3.4.22.53; 702693-80-9; calcium-activated neutral protease II; m-calpain; milli-calpain. Cat No: EXWM-4228. | |
| calpain-3 | This Ca2+-dependent enzyme is found in skeletal muscle and is genetically linked to limb girdle muscular dystrophy type 2A. The enzyme is activated by autoproteolytic cleavage of insertion sequence 1 (IS1),which allows substrates and inhibitors gain access to the active site. Substrates include the protein itself and connectin/titin. Belongs in peptidase family C2. Group: Enzymes. Synonyms: p94; calpain p94; CAPN3; muscle calpain;calpain 3; calcium-activated neutral proteinase 3; muscle-specific calcium-activated neutral protease 3; CANP 3; calpain L3. Enzyme Commission Number: EC 3.4.22.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4229; calpain-3; EC 3.4.22.54; p94; calpain p94; CAPN3; muscle calpain;calpain 3; calcium-activated neutral proteinase 3; muscle-specific calcium-activated neutral protease 3; CANP 3; calpain L3. Cat No: EXWM-4229. | |
| Collagenase AF-1 GMP Grade | Collagenase AF-1 GMP Grade, often in combination with Neutral Protease AF GMP Grade, is suitable for the dissociation of sensitive cells from several tissues, such as pancreas, liver and dental pulp. It has been shown to be highly effective for the isolation of islets of Langerhans from human pancreas intended for transplantation. Applications: Collagenase af-1 gmp grade is suitable for cell isolation from several tissue types intended for clinical applications. it is often used in combination with neutral protease af gmp grade. Group: Enzymes. Synonyms: Collagenase AF-1; Collagenase; Collagenase AF-1 GMP; Collagenase GMP. Enzyme Commission Number: EC 3.4.24.3. CAS No. 9001-12-1. Collagenase. Activity: ≥ 3.00 U/mg. Storage: 2 to 8 °C. Form: Lyophilized powder. Source: Clostridium histolyticum. Collagenase AF-1; Collagenase; Collagenase AF-1 GMP; Collagenase GMP. Cat No: NATE-1919. | |
| deuterolysin | Proteolytic activity found in Penicillium roqueforti, P. caseicolum, Aspergillus sojae and A. oryzae. Optimum pH of 5 for digesting various proteins. Strong action on protamine and histones. Insensitive to phosphoramidon. About 20 kDa. A distinct Aspergillus sojae endopeptidase is larger and has a neutral pH optimum. Type example of peptidase family M35. Formerly included in EC 3.4.24.4. Group: Enzymes. Synonyms: Penicillium roqueforti protease II; microbial neutral proteinase II; acid metalloproteinase; neutral proteinase II; Penicillium roqueforti metalloproteinase. Enzyme Commission Number: EC 3.4.24.39. CAS No. 247028-11-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4321; deuterolysin; EC 3.4.24.39; 247028-11-1; Penicillium roqueforti protease II; microbial neutral proteinase II; acid metalloproteinase; neutral proteinase II; Penicillium roqueforti metalloproteinase. Cat No: EXWM-4321. | |
| Dispase II | Dispase II is a neutral protease that hydrolyzes the N-terminal peptide bonds of non-polar amino acid residues. It may be used for separating many tissues and cells grown in vitro. The enzyme is very gentle and does not damage cell membranes. It can also be used to prevent clumping in suspension cultures. This protease cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin.[3] Dispase II is specific for the cleavage of Leucine-Phenylalanine bonds. Ca2+, Mg2+, Mn2+, Fe2+, Fe3+ and Al3+ activate the enzyme. EDTA, EGTA, Hg2+ and other heavy metals inhibit the enzyme activity.[6] The enzyme contains 1g-atom of zinc per g-mol of purified enzyme. If this zinc component is removed by chelating agents such as EDTA or EGTA, an inactive apoenzyme is obtained. The enzyme is not inhibited by serum. Group: Biochemicals. Grades: Highly Purified. CAS No. 42613-33-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. |  Worldwide |
| histolysain | From the protozoan, Entamoeba histolytica. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: histolysin; histolysin; Entamoeba histolytica cysteine proteinase; amebapain; Entamoeba histolytica cysteine protease; Entamoeba histolytica neutral thiol proteinase. Enzyme Commission Number: EC 3.4.22.35. CAS No. 92228-52-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4210; histolysain; EC 3.4.22.35; 92228-52-9; histolysin; histolysin; Entamoeba histolytica cysteine proteinase; amebapain; Entamoeba histolytica cysteine protease; Entamoeba histolytica neutral thiol proteinase. Cat No: EXWM-4210. | |
| insulysin | A 110 kDa cytosolic enzyme, known from mammals and the fruit fly, Drosophila melanogaster. Inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not by phosphoramidon. In peptidase family M16 (pitrilysin family). Group: Enzymes. Synonyms: insulinase; insulin-degrading enzyme; insulin protease; insulin proteinase; insulin-degrading neutral proteinase; insulin-specific protease; insulin-glucagon protease; metalloinsulinase; IDE. Enzyme Commission Number: EC 3.4.24.56. CAS No. 9013-83-6. IDE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4338; insulysin; EC 3.4.24.56; 9013-83-6; insulinase; insulin-degrading enzyme; insulin protease; insulin proteinase; insulin-degrading neutral proteinase; insulin-specific protease; insulin-glucagon protease; metalloinsulinase; IDE. Cat No: EXWM-4338. | |
| mannan-binding lectin-associated serine protease-2 | Mannan-binding lectin (MBL) recognizes patterns of neutral carbohydrates, such as mannose and N-acetylglucosamine, on a wide range of microbial surfaces and is able to initiate activation of the lectin pathway of complement. This enzyme displays C1s-like esterolytic activity (cf. EC 3.4.21.42, complement subcomponent C1s). It also cleaves C4 and C2 with efficiencies that are relatively higher than those of EC 3.4.21.42. Belongs in peptidase family S1A. Group: Enzymes. Synonyms: MASP-2; MASP2; MBP-associated serine protease-2; mannose-binding lectin-associated serine protease-2; p100; mannan-binding lectin-associated serine peptidase 2. Enzyme Commission Number: EC 3.4.21.104. CAS No. 214915-16-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4099; mannan-binding lectin-associated serine protease-2; EC 3.4.21.104; 214915-16-9; MASP-2; MASP2; MBP-associated serine protease-2; mannose-binding lectin-associated serine protease-2; p100; mannan-binding lectin-associated serine peptidase 2. Cat No: EXWM-4099. | |
| Matrix Metalloproteinase-3 from Human, Recombinant | Matrix metalloproteinase-3 (MMP-3) also known as stromelysin-1 and transin (EC 3.4.24.17) cleaves a number of substrates including cartilage proteoglycan, collagen types II, III, IV, V and IX, fibronectin, laminin, and can activate MMP 1. MMP-3 is secreted as 57 and 59 kDa proenzymes and can be activated in vitro by organomercurials (e.g., 4 aminophenylmercuric acetate, APMA) and in vivo by proteases via intermediate forms to a 45 kDa active MMP 3 enzyme. Further autolysis to a 28 kDa form can also occur. MMP-3 is thought to play an important role in pathophysiological degradation processes associated with conditions such as rheumatoid arthritis and cancer cell invas...C 3.4.24.17; matrix metalloproteinase 3; proteoglycanase; collagenase activating protein; procollagenase activator; transin; MMP-3; neutral proteoglycanase; stromelysin; collagen-activating protein. Enzyme Commission Number: EC 3.4.24.17. CAS No. 79955-99-0. Purity: >95% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 57 kDa. Storage: < -70°C; Avoid freeze/thaw. Form: Lyophilized from 100 mM NaCl, 50 mM HEPES, pH 7.3. Species: Human. Stromelysin 1; EC 3.4.24.17; matrix metalloproteinase 3; proteoglycanase; collagenase activating protein; procollagenase activator; transin; MMP-3; neutral proteoglycanase; stromelysin; collagen-activating protein. Cat No: NATE-0861. | |
| Metalloproteinase from Staphylococcus aureus | A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal. An example of this would be meltrin which plays a significant role in the fusion of muscle cells during embryo development, in a process known as myogenesis. Most metalloproteases require zinc, but some use cobalt. The metal ion is coordinated to the protein via three ligands. The ligands co-ordinating the metal ion can vary with histidine, glutamate, aspartate, lysine, and arginine. The fourth coordination position is taken up by a labile water molecule. Treatment with chelating agents such as EDTA leads to complete inactivation. EDTA is a metal chelator that rem...tial for activity. They are also inhibited by the chelator orthophenanthroline. Applications: Enzyme used for structural and enzymological studies. specificity similar to that of thermolysin with preference to hydrophobic p1' residues. Group: Enzymes. Synonyms: Aureolysin. Enzyme Commission Number: EC 3.4.24.29. CAS No. 39335-13-2. Purity: > 95 % (SDS-PAGE). Metalloproteinase. Mole weight: 28000. Storage: at -15 °C to -25 °C. Form: Lyophilized from 20 mM Tris/HCl pH 7.8, containing 5-10 mM CaCl2. Source: Staphylococcus aureus. Aureolysin; EC 3.4.24.29; Metalloproteinase; Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Cat No: NATE-1617. | |
| Native Bacillus polymyxa Dispase | Dispase is a protease which cleaves fibronectin, collagen IV, and to a lesser extent collagen I. It is found in some bacteria and can be isolated from culture filtrates of Bacillus polymyxa. It can be extracted, purified, and used in research. It can be particularly useful to separate embryonic epithelia and mesenchyme. Dispase II is specific for the cleavage of Leucine-Phenylalanine bonds. Dispase is often used to digest adhering primary cells in culture, since this treatment turned out to be milder than trypsin digestion. Applications: Dispase is a protease which cleaves fibronectin, collagen iv, and to a lesser extent collagen i. it is found in some bacteria and can be iso...d used in research. it can be particularly useful to separate embryonic epithelia and mesenchyme. dispase ii is specific for the cleavage of leucine-phenylalanine bonds. dispase is often used to digest adhering primary cells in culture, since this treatment turned out to be milder than trypsin digestion (sinclair et al., 2013). a recent article also finds that dispase can digest serine-phenylalanine. Group: Enzymes. Synonyms: Dispase; 42613-33-2; Proteinase; Bacillus polymyxa neutral. CAS No. 42613-33-2. Dispase. Activity: ~0.4 unit/mg solid. Storage: 2-8°C. Form: powder. Source: Bacillus polymyxa. Dispase; 42613-33-2; Proteinase; Bacillus polymyxa neutral. Cat No: NATE-0193. | |
| Native Bacillus polymyxa Dispase I | Dispase I is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. It can also separate intact epithelial sheets in culture from the substratum. The enzyme preserves the viability of the epithelial cells while cleaving the basement membrane zone region. It can also be used to prevent clumping in suspension cultures. This protease cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin. It hydrolyzes N-terminal peptide bonds of non-polar amino acid residues. It preferentially attacks denatured and intercellular proteins with exposed hydrophobic amino acid residues. Ca2+, Mg2+, Mn2+...e i has also been used in a study to investigate a dityrosine-based substrate for a protease assay. dispase i has been used in lung digestion and processing for flow staining, as well as for cd4 cell isolation in mice. the enzyme has also been used to digest excised wounds and a small amount of surrounding skin for the detection of gfp+ (green fluorescence protein) cells. this study to investigated the effect of differentiation and angiogenesis of bone marrow-derived mesenchymal stem cells on wound healing. it has also been used to remove the epidermis during the isolation of dermal fibroblasts from mice. Group: Enzymes. Synonyms: Dispase I; Dispase; 42613-33-2; Protease fro | |
| Native Bacillus polymyxa Dispase II | Dispase II is a neutral protease that hydrolyzes the N-terminal peptide bonds of non-polar amino acid residues. It may be used for separating many tissues and cells grown in vitro. The enzyme is very gentle and does not damage cell membranes. It can also be used to prevent clumping in suspension cultures. This protease cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin. Dispase II is specific for the cleavage of Leucine-Phenylalanine bonds. Ca2+, Mg2+, Mn2+, Fe2+, Fe3+ and Al3+ activate the enzyme. EDTA, EGTA, Hg2+ and other heavy metals inhibit the enzyme activity. The enzyme contains 1g-atom of zinc per g-mol of purif... it has been used in the treatment of rat heart pieces during the isolation of mitochondria from rat heart. it has also been used for the isolation of dental pulp stem cells (dpscs) by enzymatic hydrolysis. these cells have been compared with dpscs isolated by explant method to analyse their stem cell and differentiation properties. Group: Enzymes. Synonyms: Dispase II; Dispase; 42613-33-2; Protease from Bacillus polymyxa. CAS No. 42613-33-2. Dispase. Activity: > 0.5 units/mg solid. Storage: 2-8°C. Form: lyophilized powder containing calcium acetate and milk sugar. Source: Bacillus polymyxa. Dispase II; Dispase; 42613-33-2; Protease from Bacillus polymyxa. Cat No: NATE-0192. | |
| Native Human Calpain 1 | Caplain 1 is a neutral calcium-dependent cysteine protease containing the EF-hand motif. The protease consists of two subunits; the larger subunit has four domains that are homologous with papain and calmodulin. The smaller subunit has one domain that shares homology with calmodulin. It is activated by micromolar levels of calcium and hence, it is also called as micro-calpain. Its activation leads to cellular protein degradation, neuronal cell degeneRation, and autoimmune demyelinating diseases such as multiple sclerosis. > 95% (sds-page). Applications: Human calpain 1 has been used in a study to assess how the crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition. human calpain 1 has also been used in a study to investigate the synthesis, biological evaluation and molecular modelling of n-heterocyclic dipeptide aldehydes as selective calpain inhibitors. Group: Enzymes. Synonyms: calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Enzyme Commission Number: EC 3.4.22.52. CAS No. 78990-62-2. Calpain 1. Storage: -70°C. Form: aqueous glycerol solution. Source: Human. calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Cat No: NATE-0100. | |
| Native Human Cathepsin G | Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, but it is most closely related to other immune serine proteases, such as neutrophil elastase and the granzymes. Cathepsin G may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. It also localizes to Neutrophil extracellular traps (NETs), via its high affinity for DNA, an unusual property for serine proteases. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Group: Enzymes. Synonyms: CTSG; cathepsin G; CG; CATG; EC 3.4.21.20; chymotrypsin-like proteinase; neutral proteinase. Enzyme Commission Number: EC 3.4.21.20. CAS No. 56645-49-9. Purity: > 96% (SDS-PAGE). CTSG. Activity: > 5 U/mL. Appearance: Clear, colorless solution. Storage: 2-8°C. Form: Liquid. Source: Human Neutrophils. Species: Human. CTSG; cathepsin G; CG; CATG; EC 3.4.21.20; chymotrypsin-like proteinase; neutral proteinase. Cat No: NATE-0173. | |
| Native Human Tryptase | Tryptase is a member of the serine protease S1 family. It is the predominant neutral protease of the mast cell granules. Within the mast cell granule it exists as a heparin-stabilized active tetramer. Stabilization is a result of the high negative charge density of the glycosaminoglycan. This stabilization activity is observed with heparins with a MW > 6 kDa as well as other glycosaminoglycans such as dextran sulfate or chondroitin sulfates. Removal of heparin results in dissociation of the tetramer and inactivation of the enzyme. High concentrations of NaCl will result in the dissociation of heparin. Tryptase is a glycoprotein released from mast cells during anaphylaxis, which pe...acterized recombinant rat mast cell protease 7 expressed in pichia pastoris. tryptase has also been used in a study to investigate drug allergies in mast cell disease. Group: Enzymes. Synonyms: tryptase; mast cell tryptase; mast cell protease II; skin tryptase; lung tryptase; pituitary tryptase; mast cell neutral proteinase; mast cell tryptase; mast cell neutral proteinase; mast cell serine proteinase II; mast cell proteinase II; mast cell serine proteinase tryptase; rat mast cell protease II; tryptase M; EC 3.4.21.59. Enzyme Commission Number: EC 3.4.21.59. CAS No. 97501-93-4. Tryptase. Mole weight: Molecular Weight: ~135 kDa (Human) (Non-covalently linked tetramer with two sets o | |
| Native Porcine Calpain 1 | Caplain 1 is a neutral calcium-dependent cysteine protease containing the EF-hand motif. The protease consists of two subunits; the larger subunit has four domains that are homologous with papain and calmodulin. The smaller subunit has one domain that shares homology with calmodulin. It is activated by micromolar levels of calcium and hence, it is also called as micro-calpain. Its activation leads to cellular protein degradation, neuronal cell degeneRation, and autoimmune demyelinating diseases such as multiple sclerosis. Group: Enzymes. Synonyms: μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Purity: > = 95% by SDS-PAGE. Calpain 1. Mole weight: 110000. Stability: > 1 year. Storage: -70°C or lower; avoid freeze/thaw cycles. Form: Frozen. Source: Porcine Erythrocytes. Species: Porcine. calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Cat No: NATE-1625. | |
| Neutral proteinase from Bacillus sp. | Neutral proteinase from Bacillus sp. Applications: This enzyme is useful for synthesis of oligopeptides, for proteolysis of insoluble protein and for structural investigation of the protein. Group: Enzymes. Synonyms: Neutral proteinase; Cathepsin G; Microbial metalloproteinase; EC 3.4.24.4. Enzyme Commission Number: EC 3.4.24.4. CAS No. 70851-98-8. Neutral Protease. Mole weight: approx. 25,000 (SDS-PAGE). Activity: 1000U/mg-solid or more. Stability: Stable at 5°C for at least one year. Appearance: White amorphous powder or granule. Source: Bacillus sp. Neutral proteinase; Cathepsin G; Microbial metalloproteinase; EC 3.4.24.4. Cat No: DIA-273. | |
| Protease for flavors | Protease used in a neutral to alkaline environment. Used to develop savory flavors and to debitter protein hydrolysates. Applications: Flavors in high-protein flours used in baking. Group: Enzymes. CAS No. 37259-58-8. Protease. Appearance: powder or liquid. Acid Protease; for beer; Acid Protease; ethanol; baijiu Enzyme; beer Enzyme; brewage Enzyme; Acid Protease for beer; BER-1512. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: PRO-1827. | |
| snapalysin | Type example of peptidase family M7. Group: Enzymes. Synonyms: small neutral protease; SnpA gene product (Streptomyces lividans). Enzyme Commission Number: EC 3.4.24.77. CAS No. 945859-47-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4361; snapalysin; EC 3.4.24.77; 945859-47-2; small neutral protease; SnpA gene product (Streptomyces lividans). Cat No: EXWM-4361. | |
| Staphylokinase, Recombinant | Staphylokinase (SAK) is a 136-amino acidenzymefrom Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen, which in turn can degrade various host proteins during infection. Staphylokinase recombinant produced in e. coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 15.5 kd.the staphylokinase is purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Staphylokinase; SakSTAR; Neutral proteinase; Protease III; SAK. Purity: Greater than 97.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. SAK. Mole weight: 15.5 kDa. Activity: 4600 IU/mg. Stability: Lyophilized SAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SAK should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered White lyophilized (freeze-dried) powder. Source: E. coli. Staphylokinase; SakSTAR; Neutral proteinase; Protease III; SAK. Cat No: NATE-0915. | |
| tryptase | Occurs as a tetrameric molecule with high affinity for heparin, in mast cell granules. In peptidase family S1 (trypsin family). Not inhibited by α1-proteinase inhibitor or α2-macroglobulin. Group: Enzymes. Synonyms: mast cell tryptase; mast cell protease II; skin tryptase; lung tryptase; pituitary tryptase; mast cell neutral proteinase; mast cell tryptase; mast cell neutral proteinase; mast cell serine proteinase II; mast cell proteinase II; mast cell serine proteinase tryptase; rat mast cell protease II; tryptase M. Enzyme Commission Number: EC 3.4.21.59. CAS No. 97501-93-4. Tryptase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4149; tryptase; EC 3.4.21.59; 97501-93-4; mast cell tryptase; mast cell protease II; skin tryptase; lung tryptase; pituitary tryptase; mast cell neutral proteinase; mast cell tryptase; mast cell neutral proteinase; mast cell serine proteinase II; mast cell proteinase II; mast cell serine proteinase tryptase; rat mast cell protease II; tryptase M. Cat No: EXWM-4149. | |
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