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| Product | Description | |
|---|---|---|
| Nexinhib20 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Nexinhib20 | Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 ?M) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and ?2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331949-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125792. |  |
| Nexinhib20 | Nexinhib20 is a Rab27 inhibitor (IC50 = 330 nM) that selectively inhibits neutrophil exocytosis. It suppresses extracellular production of superoxide anion and expression of cytochrome b in plasma membrane. Synonyms: Neutrophil exocytosis inhibitor 20; 4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one. Grades: ≥98% by HPLC. CAS No. 331949-35-0. Molecular formula: C15H16N4O3. Mole weight: 300.31. |  |
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