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| Product | Description | |
|---|---|---|
| Niraparib | Niraparib. Alternative Names: (S)-tert-Butyl 3-(4-aminophenyl)piperidine-1-carboxylate. tert-butyl (3s)-3-(4-aminophenyl)piperidine-1-carboxylate. 1-Piperidinecarboxylic acid, 3-(4-aminophenyl)-, 1,1-dimethylethyl ester, (3S)-. (S)-tert-butyl3-(4-aMinophenyl)piperidine-1-carboxylate. CAS No. 1171197-20-8. Product ID: INT1171197208. Molecular formula: C16H24N2O2. Mole weight: 276.37. SMILES: CC(C)(C)OC(=O)N1CCC[C@H](C1)C2=CC=C(C=C2)N. Category: Intermediates. |  |
| Niraparib | Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827. CAS No. 1038915-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10619. |  |
| Niraparib hydrochloride | Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827 hydrochloride. CAS No. 1038915-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10619A. | |
| Niraparib impurity 1 | Niraparib impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038915-58-0. Molecular formula: C19H20N4O. Mole weight: 320.4. Catalog: APB1038915580. |  |
| Niraparib impurity 7 | Niraparib impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038915-73-9. Molecular formula: C26H28N4O4S. Mole weight: 492.59. Catalog: APB1038915739. | |
| Niraparib impurity 9 | Niraparib impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1334823-70-9. Molecular formula: C11H16N2. Mole weight: 176.26. Catalog: APB1334823709. | |
| Niraparib tosylate | Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC 50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827 tosylate. CAS No. 1038915-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10619B. | |
| Niraparib tosylate hydrate | Niraparib (MK-4827) tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827 tosylate hydrate. CAS No. 1613220-15-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10619E. | |
| 2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide | 2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. It exhibits over 330-fold selectivity for PARP3, V-PARP, and Tank1. Synonyms: 2H-Indazole-7-carboxamide, 2-[4-(3-piperidinyl)phenyl]-; 2-[4-(3-Piperidinyl)phenyl]-2H-indazole-7-carboxamide; 2-[4-(-3-Piperidyl)phenyl]-2H-indazol-7-methanamide; MK-4827 Racemate free base; Niraparib Racemate free base. Grade: ≥95%. CAS No. 1038915-75-1. Molecular formula: C19H20N4O. Mole weight: 320.39. |  |
| 2-?Chloro-?1-?(3-?fluorobenzyloxy)?-?4-?nitrobenzene | 2-?Chloro-?1-?(3-?fluorobenzyloxy)?-?4-?nitrobenzene is a reagent used in the synthesis of novel indole-2-carboxamide derivative as anti-inflammatory agents used in the treatment of sepsis. Also an intermediate of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. Group: Biochemicals. Grades: Highly Purified. CAS No. 443882-99-3. Pack Sizes: 5g, 10g. Molecular Formula: C13H9ClFNO3, Molecular Weight: 281.67. US Biological Life Sciences. |  Worldwide |
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