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| Product | Description | |
|---|---|---|
| nitric oxide dioxygenase | A flavohemoglobin (FAD). It has been proposed that FAD functions as the electron carrier from NADPH to the ferric heme prosthetic group. Group: Enzymes. Enzyme Commission Number: EC 1.14.12.17. CAS No. 214466-78-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0686; nitric oxide dioxygenase; EC 1.14.12.17; 214466-78-1. Cat No: EXWM-0686. |  |
| nitric oxide reductase (cytochrome c) | The enzyme from Pseudomonas aeruginosa contains a dinuclear centre comprising a non-heme iron centre and heme b3, plus heme c, heme b and calcium; the acceptor is cytochrome c551. Group: Enzymes. Enzyme Commission Number: EC 1.7.2.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1620; nitric oxide reductase (cytochrome c); EC 1.7.2.5. Cat No: EXWM-1620. | |
| nitric oxide reductase (menaquinol) | Contains copper. Group: Enzymes. Enzyme Commission Number: EC 1.7.5.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1630; nitric oxide reductase (menaquinol); EC 1.7.5.2. Cat No: EXWM-1630. | |
| nitric oxide reductase [NAD(P)+, nitrous oxide-forming] | A heme-thiolate protein (P-450). The enzyme from Fusarium oxysporum utilizes only NADH, but the isozyme from Trichosporon cutaneum utilizes both NADH and NADPH. The electron transfer from NAD(P)H to heme occurs directly, not requiring flavin or other redox cofactors. Group: Enzymes. Synonyms: fungal nitric oxide reductase; cytochrome P450nor; NOR (ambiguous). Enzyme Commission Number: EC 1.7.1.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1607; nitric oxide reductase [NAD(P)+, nitrous oxide-forming]; EC 1.7.1.14; fungal nitric oxide reductase; cytochrome P450nor; NOR (ambiguous). Cat No: EXWM-1607. | |
| Nitric Oxide Synthase, Inducible from mouse, Recombinant | Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). The inducible isoform, iNOS, is involved in immune response, binds calmodulin at physiologically relevant concentrations, and produces NO as an immune defense mechanism, as NO is a free ...DPH); Inducible Nitric Oxide Synthase; NOS II; iNOS; macNOS; EC 1.14.13.39; NOSs. Enzyme Commission Number: EC 1.14.13.39. CAS No. 125978-95-2. NOSs. Mole weight: mol wt 130 kDa (homodimer); mol wt 130 kDa (subunit, homodimer). Storage: -70°C. Form: buffered aqueous solution; Solution in 50 mM HEPES, pH 7.4, with 10% glycerol, 8 μM tetrahydrobiopterin. Source: E. coli. Species: Mouse. nitric oxide synthetase; endothelium-derived relaxation factor-forming enzyme; endothelium-derived relaxing factor synthase; NO synthase; NADPH-diaphorase; nitric-oxide synthase (NADPH); Inducible Nitric Oxide Synthase; NOS II; iNOS; macNOS; EC 1.14.13.39; NOSs. Cat No: NATE-0489. | |
| Nitric Oxide Synthase, Neuronal Inhibitor I - CAS 357965-99-2 | The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-Nitric Oxide Synthase, Brain (1409-1429) antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Nitric Oxide Synthase, Endothelial (1185-1205) antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Nitric Oxide Synthase, Endothelial (596-609) antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Nitric Oxide Synthase, Inducible antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Nitric Oxide Synthase, Universal antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Diethylamine (nitric oxide) Adduct | A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 56329-27-2. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Inducible Nitric Oxide Synthase, Control Peptide (iNOS, iNOS 2, mNOS) | Sequence: Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 150nmole. US Biological Life Sciences. | Worldwide |
| Monoclonal Anti-Nitric Oxide Synthase, Brain (1-181) antibody produced in mouse | clone NOS-B1, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Nitric Oxide Synthase, Endothelial antibody produced in mouse | clone NOS-E1, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Nitric Oxide Synthase, Inducible antibody produced in mouse | clone NOS-IN, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Nitric Oxide Synthase, Universal antibody produced in mouse | clone NOS-3F7-B11-B5, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| nitric-oxide synthase (NADPH) | Binds FAD, FMN, heme (iron protoporphyrin IX) and tetrahydrobiopterin. This eukaryotic enzyme, which is found in plants and animals, consists of oxygenase and reductase domains that are linked via a regulatory calmodulin-binding domain. Upon calcium-induced calmodulin binding, the reductase and oxygenase domains form a complex, allowing electrons to flow from NADPH via FAD and FMN to the active center. May produce superoxide under certain conditions. cf. EC 1.14.13.165, nitric-oxide synthase [NAD(P)H dependent]. Group: Enzymes. Synonyms: nitric oxide synthetase; endothelium-derived relaxation factor-forming enzyme; endothelium-derived relaxing factor synthase; NO synthase; NADPH-diaphorase. Enzyme Commission Number: EC 1.14.13.39. CAS No. 125978-95-2. NOSs. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0846; nitric-oxide synthase (NADPH); EC 1.14.13.39; 125978-95-2; nitric oxide synthetase; endothelium-derived relaxation factor-forming enzyme; endothelium-derived relaxing factor synthase; NO synthase; NADPH-diaphorase. Cat No: EXWM-0846. | |
| nitric-oxide synthase [NAD(P)H] | Binds heme (iron protoporphyrin IX) and tetrahydrobiopterin. Most of the bacterial and archaeal enzymes consist of only an oxidase domain and function together with bacterial ferredoxins. The enzyme from the Δ-proteobacterium Sorangium cellulosum also includes a reductase domain that binds FAD, FMN and a [2Fe-2S] cluster. The similar enzymes from plants and animals use only NADPH as acceptor (cf. EC 1.14.13.39). Group: Enzymes. Synonyms: nitric oxide synthetase; NO synthase. Enzyme Commission Number: EC 1.14.13.165. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0764; nitric-oxide synthase [NAD(P)H]; EC 1.14.13.165; nitric oxide synthetase; NO synthase. Cat No: EXWM-0764. | |
| Spermine Bis (Nitric Oxide) Adduct | A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies. Group: Biochemicals. Alternative Names: N1- [4- [1- (3-Aminopropyl) -2-hydroxy-2-nitrosohydrazinyl] butyl] -1, 3-propanediamine. Grades: Highly Purified. CAS No. 136587-13-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Synthase,nitric oxide | Synthase,nitric oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NCNOS;NCNOS, RAT;NCNOS (RAT RECOMBINANT);NITRIC OXIDE SYNTHASE (NEURONAL);NITRIC OXIDE SYNTHASE, NEURONAL RAT;NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE, CONSTITUTIVE, RAT BRAIN;NITRIC OXIDE SYNTHASE, CONSTITUTIVE, RAT NEURONAL. Product Category: Heterocyclic Organic Compound. CAS No. 125978-95-2. Product ID: ACM125978952. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 10-Hydroxydecanoic acid | 10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 ( IRF-1 ), which reduces the production of interleukin 6 ( IL-6 ) and nitric oxide ( NO ) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 15139; 10-HDAA. CAS No. 1679-53-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-Y0148. |  |
| 10Z-Hymenialdisine | Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C??H??BrN?O?, Method for Determining. US Biological Life Sciences. | Worldwide |
| (11 β , ?16α ) ?-9-?Fluoro-?11-?hydroxy-?17, ?21-?[ (1-?methoxypentylidene) ?bis (oxy) ?]?-?16-?methyl-pregna-?1, ?4-?diene-?3, ?20-?dione | (11 β , ?16α ) ?-9-?Fluoro-?11-?hydroxy-?17, ?21-?[ (1-?methoxypentylidene) ?bis (oxy) ?]?-?16-?methyl-pregna-?1, ?4-?diene-?3, ?20-?dione is an intermediate in synthesizing Dexamethasone Valerate (D298870), an impurity of Dexamethasone (D298800), which is a glucocorticoid that is used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1062-64-2. Pack Sizes: 25mg, 50mg. Molecular Formula: C28H39FO6, Molecular Weight: 490.6. US Biological Life Sciences. | Worldwide |
| 1,2-Diaminoanthraquinone | 1,2-Diaminoanthraquinone is a sensitivity, specificity and nontoxic nitric oxide ( NO ) fluorescent probe. 1,2-Diaminoanthraquinone can be used to detect NO productions in live cell and animals with a maximum of absorption at about 540 nm and a detection limit of 5 μM for NO [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1758-68-5. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-W013435. | |
| 1,2-Diaminoanthraquinone | 1,2-Diaminoanthraquinone is for the direct detection of nitric oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1758-68-5. Pack Sizes: 25g, 50g. Molecular Formula: C14H10N2O2, Molecular Weight: 238.24. US Biological Life Sciences. | Worldwide |
| 1400W | 1400W is a selective inducible nitric oxide synthase (NOS) inhibitor (Ki = 7 nM, IC50=2.0 uM). By suppressing the induction of inducible NOS, 1400W exhibits an therapeutical effect on ischemia reperfusion injury, acute hypobaric hypoxia/reoxygenation-induced cognitive deficits and tumor. Uses: A selective inducible nitric oxide synthase (inos) inhibitor. a long-acting human inos inhibitor possessing an ic50 value of 2.0um. Synonyms: N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE. Grades: >98%. CAS No. 180001-34-7. Molecular formula: C10H15N3. Mole weight: 177.251. |  |
| 1400W - CAS 214358-33-5 | A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM). Group: Fluorescence/luminescence spectroscopy. | |
| 1400W dihydrochloride | 1400W is a selective inducible nitric oxide synthase (NOS) inhibitor (Ki=7nM). By suppressing the induction of inducible NOS, 1400W exhibits an therapeutical effect on ischemia reperfusion injury, acute hypobaric hypoxia/reoxygenation-induced cognitive deficits and tumor. Uses: A selective inducible nitric oxide synthase (inos) inhibitor which has the potential for treatment of ischemia reperfusion injury,acute hypobaric hypoxia and tumor. Synonyms: N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride; 1400W HCl; 1400W hydrochloride; 1400W (hydrochloride). Grades: >98%. CAS No. 214358-33-5. Molecular formula: C10H17Cl2N3. Mole weight: 250.167. | |
| 1400W Dihydrochloride | 1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase ( iNOS ) inhibitor, with a K d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 214358-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18731. | |
| 1400W Dihydrochloride | Cell-permeable. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd ≤7nM). In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with K? values of 2 and 50uM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices. Group: Biochemicals. Alternative Names: N- (3- (Aminomethyl) benzyl) acetamidine 2HCl. Grades: Highly Purified. CAS No. 214358-33-5. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| 1400W dihydrochloride (N- (3- (Aminomethyl) benzyl) acetamidine. 2HCl) | A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd < 7 nM). Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki < 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki < 50 µM). Inhibits tumor growth. Increases vasoconstriction to noradrenaline. Improves contractile function. Improves stroke outcome and decreases glutamate release. Anti-inflammatory. Group: Biochemicals. Alternative Names: N- (3- (Aminomethyl) benzyl) acetamidine. 2HCl. Grades: Highly Purified. CAS No. 214358-33-5. Pack Sizes: 5mg, 25mg, 100mg. Molecular Formula: C10H15N3. 2HCl. US Biological Life Sciences. | Worldwide |
| 1,4:3,6-Dianhydro-2-nitro-D-glucitol | 1,4:3,6-Dianhydro-2-nitro-D-glucitol is a Nitric Oxide donor with biomedicine applications in research of pharmaceutical formulation to enhance drug delivery. Synonyms: Isosorbide 2-nitrate; 6-Nitrooxyhexahydro-furo[3,2-b]furan-3-ol; 1,4:3,6-Dianhydro-D-glucitol 2-mononitrate. CAS No. 16106-20-0. Molecular formula: C6H9NO6. Mole weight: 191.14. | |
| 14-Deoxyandrographolide | 14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 4176-97-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4323. | |
| 1,5-Isoquinolinediol | 1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. 1,5-Isoquinolinediol is also an inducible nitric oxide synthase (NOS2) inhibitor. 1,5-Isoquinolinediol significantly inhibited mitochondrial membrane potential loss, AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 1,5-Dihydroxyisoquinoline; Isoquinoline-1,5-diol; 5-Hydroxy-1(2H)-isoquinolinone; 5-Hydroxyisocarbostyril. Grades: 99%. CAS No. 5154-2-9. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| 1,5-Isoquinolinediol | PARP-1 inhibitor. Neuroprotectant. Blocks nitric oxide-induced neuronal toxicity. Potent iNOS (inducible nitric oxide synthase/NOS II) inhibitor. Stimulates homologous recombination. Group: Biochemicals. Alternative Names: 5-Hydroxy-1(2H)-isoquinolinone, 1,5-Dihydroxyisoquinoline. Grades: Highly Purified. CAS No. 5154-2-9. Pack Sizes: 5mg, 25mg, 100mg. Molecular Formula: C9H7NO2. US Biological Life Sciences. | Worldwide |
| 16α-Dexamethasone 9,11-Epoxide 21-Propionate | Dexamethasone 9,11-Epoxide 21-Propionate is an impurity of Dexamethasone (D298800) which is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase. Group: Biochemicals. Grades: Highly Purified. CAS No. 494870-08-5. Pack Sizes: 5mg, 50mg. Molecular Formula: C25H32O6. US Biological Life Sciences. | Worldwide |
| 16-Deacetylfusidic Acid γ-Lactone | 16-Deacetylfusidic Acid γ-Lactone is a metabolite of the drug Fusidic Acid (F865500). Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 4701-54-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C29H44O4, Molecular Weight: 456.66. US Biological Life Sciences. | Worldwide |
| 16-Epi-deacetyl-fusidic Acid | 16-Epi-deacetyl-fusidic Acid (Fusidic Acid EP Impurity I) is a metabolite of fusidic acid (F865500) which is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells and inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 5951-83-7. Pack Sizes: 25mg, 250mg. Molecular Formula: C29H46O5, Molecular Weight: 474.67. US Biological Life Sciences. | Worldwide |
| 1-Pyrrolidinecarbodithio ic Acid Ammonium Salt | 1-Pyrrolidinecarbodithio ic Acid induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells. It also prevents induction of nitric oxide synthetase by inhibiting translation of NOS mRNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 5108-96-3. Pack Sizes: 15g, 100g. Molecular Formula: C5H12N2S2. US Biological Life Sciences. | Worldwide |
| 21-Hydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione | 21-Hydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione is the impurity of Dexamethasone (D298800), which is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation; it inhibits the induction of nitric oxide synthase. Group: Biochemicals. Grades: Highly Purified. CAS No. 56016-90-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C22H28O3, Molecular Weight: 340.46. US Biological Life Sciences. | Worldwide |
| 2,3-Diaminonaphthalene | 2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also an inhibitor of nitric oxide (NO) formation. Synonyms: naphthalene-2,3-diamine; 2,3-diaminonaphthalene; 2,3-naphthalenediamine. CAS No. 771-97-1. Molecular formula: C10H10N2. Mole weight: 158.2. | |
| 2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one | A benzoxazolone analogue that may be used to inhibit the nitric oxide synthases (NOS). Group: Biochemicals. Alternative Names: 2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one; Oxazolo[4,5-b]pyridin-2(3H)-one; 3H-Oxazolo[4,5-b]pyridin-2-one; [1,3]Oxazolo[4,5-b]pyridin-2(3H)-one. Grades: Highly Purified. CAS No. 60832-72-6. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 2- (3-Fluorophenoxy) ethylamine | 2- (3-Fluorophenoxy) ethylamine acts as a reagent in the synthesis of neuronal nitric oxide synthase inhibitors with improved cellular permeability. Di methyl tetrahydropyrazino purinediones preparation as adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 120351-93-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H10FNO, Molecular Weight: 155.169999999999. US Biological Life Sciences. | Worldwide |
| 26-Hydroxy-fusidic Acid | 26-Hydroxy-fusidic Acid is a metabolite of the drug Fusidic Acid (F865500). Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C31H48O7, Molecular Weight: 532.71. US Biological Life Sciences. | Worldwide |
| 2?,7?-Dichlorofluorescin Diacetate - CAS 4091-99-0 | Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) and nitric oxide ( NO) and for the determination of the degree of overall oxidative stress. Group: Fluorescence/luminescence spectroscopy. | |
| 27-Oxo-fusidic Acid | 27-Oxo-fusidic Acid is a metabolite of fusidic acid (F865500) which is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells and inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 1415035-94-7. Pack Sizes: 25mg, 250mg. Molecular Formula: C31H46O7, Molecular Weight: 530.69. US Biological Life Sciences. | Worldwide |
| 2-(Acetyloxy)benzoic Acid 4-(Hydroxymethyl)phenyl Ester | 2-(Acetyloxy)benzoic Acid 4-(Hydroxymethyl)phenyl Ester is an intermediate in the synthesis of a novel nitric oxide-releasing aspirin, Nitro-aspirin inhibits MCF-7 breast cancer cell growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 175077-14-2. Pack Sizes: 25mg, 50mg. Molecular Formula: C16H14O5. US Biological Life Sciences. | Worldwide |
| 2-Amino-3,4-dimethylpyridine | 2-Amino-3,4-dimethylpyridine is a dimethyl-substituted 2-aminopyridine that can be used as an inhibitor of human nitric oxide synthase. Group: Biochemicals. Grades: Highly Purified. CAS No. 823-39-2. Pack Sizes: 100mg, 1g. Molecular Formula: C7H10N2, Molecular Weight: 122.17. US Biological Life Sciences. | Worldwide |
| 2-Amino-4-methoxypyridine | 2-Amino-4-methoxypyridine is a highly selective inducible nitric oxide synthase inhibitors. Group: Biochemicals. Alternative Names: (4-Methoxypyridin-2-yl)amine; 4-(Methyloxy)-2-pyridinamine; 4-Methoxy-2-aminopyridine; 4-Methoxypyridin-2-amine. Grades: Highly Purified. CAS No. 10201-73-7. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 2-Amino-5,6,7,8-tetrahydro-6-methyl-4(1H)-pteridinone Dihydrochloride | 2-Amino-5,6,7,8-tetrahydro-6-methyl-4(1H)-pteridinone is an analog of tetrahydrobiopterin with cofactor activity for aromatic amino acid hydroxylases. It is also used to study mechanisms of nitric oxide (NO) synthase and free radical induced L-DOPA release from striatal tissue. Group: Biochemicals. Grades: Highly Purified. CAS No. 69113-63-9. Pack Sizes: 100mg, 1g. Molecular Formula: C7H13Cl2N5O, Molecular Weight: 254.12. US Biological Life Sciences. | Worldwide |
| 2-Iminobiotin | 2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with K i s of 21.8 and 37.5μM for murine iNOS and rat n-cNOS , respectively [1]. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Guanidinobiotin. CAS No. 13395-35-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-118700. | |
| 2-Iminobiotin | 2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Kis = 21.8 and 37.5 μM for mouse iNOS and rat nNOS, respectively). Synonyms: Guanidinobiotin; 1H-Thieno[3,4-d]imidazole-6-pentanoicacid, 2-amino-3a,4,6,6a-tetrahydro-, (3aR,6S,6aS)-. Grades: ≥98%. CAS No. 13395-35-2. Molecular formula: C10H17N3O2S. Mole weight: 243.3. | |
| 2-Iminobiotin hydrobromide | 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with K i s of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS , respectively [1]. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Guanidinobiotin hydrobromide. CAS No. 76985-52-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-118700A. | |
| 2-Iminopiperidine hydrochloride | 2-Iminopiperidine hydrochloride is the hydrochloride salt of 2-Iminopiperidine, which is a potent inhibitor of human nitric oxide synthase isoform (iNOS). It is selective for iNOS and is more potent than NG-methyl-L-arginine. Synonyms: 2-Pyridinamine, 3,4,5,6-tetrahydro-, hydrochloride (1:1); 2-Pyridinamine, 3,4,5,6-tetrahydro-, monohydrochloride; Piperidine, 2-imino-, monohydrochloride; (3,4,5,6-Tetrahydropyridin-2-yl)amine monohydrochloride; 3,4,5,6-Tetrahydro-2-pyridinamine Hydrochloride. Grades: ≥95%. CAS No. 16011-96-4. Molecular formula: C5H11N2Cl. Mole weight: 134.61. | |
| 2-Methylthio Uracil | A competitive inhibitor of Nitric Oxide Synthase (NOS). Group: Biochemicals. Alternative Names: 2-(Methylthio)-4(1H)-pyrimidinone; 2-(Methylthio)-4-pyrimidinol; 2-(Methylthio)-4(1H)-pyrimidinone; 2-(Methylthio)-4(3H)-pyrimidinone; 2-(Methylthio)-4-pyrimidinol; 2-(Methylthio)-4-pyrimidinone; 2-(Methylthio)-4-pyrimidone; 2-(Methylthio)pyrimidine-4(3H)-one; 2-Methylsulfanyl-3H-pyrimidin-4-one; 2- methyl sulfanylpyrimidin-4-ol; 2-Methylthio-3H-pyrimidin-4-one; 2-Methylthio-4-hydroxypyrimidine; 2-Methylthiouracil; 4-Hydroxy-2- (methylthio) pyrimidine; NSC 125339; NSC 165518. Grades: Highly Purified. CAS No. 5751-20-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2-Naphthalene methanethiol | 2-Naphthalene methanethiol is a widely used reactant and an impurity in the synthesis of N- [3- (1, 2, 3, 6-Tetrahydro-1- methyl -d3-4-pyridinyl) -1H-indol-5-yl] -2-thiophene carboximidamide (T293452), the labeled analogue of N- [3- (1, 2, 3, 6-Tetrahydro-1- methyl -4-pyridinyl) -1H-indol-5-yl] -2-thiophene carboximidamide, a neuronal nitric oxide synthase(nNOS) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1076-67-1. Pack Sizes: 500mg, 5g. Molecular Formula: C11H10S, Molecular Weight: 174.26. US Biological Life Sciences. | Worldwide |
| (2S, 4R) -4-Azido-1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester | Used in the preparation of neuronal nitric oxide synthase inhibitors. Group: Biochemicals. Alternative Names: (2S, 4R) -4-Azido-1- (tert-butoxycarbonyl) pyrrolidine-2-carboxylic Acid Methyl Ester; (2S-trans) -4-Azido-1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester. Grades: Highly Purified. CAS No. 121147-97-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2-Thiouracil | 2-Thiouracil (Thiouracil) is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a K i value of 20 μM. 2-Thiouracil antagonizes BH4-induced nNOS dimerization. 2-Thiouracil is also an antithyroid compound and a highly specific melanoma detector. 2-Thiouracil stimulates the growth of pea and corn root segments [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thiouracil. CAS No. 141-90-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0503. | |
| 3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine | 3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine is the unlabeled intermediate in the synthesis of N- [3- (1, 2, 3, 6-Tetrahydro-1- methyl -d3-4-pyridinyl) -1H-indol-5-yl] -2-thiophene carboximidamide (T293450), a labeled neuronal nitric oxide synthase(nNOS) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 116480-62-7. Pack Sizes: 500mg, 5g. Molecular Formula: C14H17N3, Molecular Weight: 227.3. US Biological Life Sciences. | Worldwide |
| 3-(1-Methyl-d3-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine | 3-(1-Methyl-d3-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine is an intermediate in the synthesis of N- [3- (1, 2, 3, 6-Tetrahydro-1- methyl -d3-4-pyridinyl) -1H-indol-5-yl] -2-thiophene carboximidamide (T293452), a labeled neuronal nitric oxide synthase(nNOS) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C14H14D3N3, Molecular Weight: 230.32. US Biological Life Sciences. | Worldwide |
| 3- (4-Chlorophenyl) -4, 5-dihydro-N'- (1-iminoethyl) -4-phenyl-N-[[4- (trifluoromethyl) phenyl]sulfonyl]-1H-pyrazole-1-carboximidamide | 3- (4-Chlorophenyl) -4, 5-dihydro-N'- (1-iminoethyl) -4-phenyl-N-[[4- (trifluoromethyl) phenyl]sulfonyl]-1H-pyrazole-1-carboximidamide, can be used in synthesis of novel dual-target compounds with antagonist/inverse agonist activity at cannabinoid receptor type 1 (CB1R) and inhibitory effect on inducible nitric oxide synthase (iNOS). Group: Biochemicals. Grades: Highly Purified. CAS No. 1610420-28-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C25H21ClF3N5O2S, Molecular Weight: 547.98. US Biological Life Sciences. | Worldwide |
| 3-Aminobenzamidine Dihydrochloride | 3-Aminobenzamidine Dihydrochloride is a reactant that has been used in the synthesis of N-phenylamidines as selective inhibitors of human neuronal nitric oxide synthase. Group: Biochemicals. Grades: Highly Purified. CAS No. 37132-68-6. Pack Sizes: 500mg, 1g. Molecular Formula: C7H11Cl2N3, Molecular Weight: 208.09. US Biological Life Sciences. | Worldwide |
| 3-Bromo-7-nitroindazole | A more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4,5-Diaminofluorescein | 4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DAF-2. CAS No. 205391-01-1. Pack Sizes: 100 μg; 250 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-D0076. | |
| 4-(NITROOXY)BUTYL (2S)-2-(6-METHOXY-2-NAPHTHYL)PROPANOATE | Naproxcinod, a nitro compound, has been found to be a nitric oxide donor as well as a cyclooxygenase inhibitor that was once studied aginast duchenne muscular dystrophy. Uses: Nitric oxide donors. Synonyms: Naproxcinod; Nitronaproxen; HCT 3012; HCT3012; HCT-3012; AZD 3582; AZD3582; AZD-3582; Naproxen-n-butyl nitrate; 4-nitrooxybutyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate. Grades: 98%. CAS No. 163133-43-5. Molecular formula: C18H21NO6. Mole weight: 347.36. | |
| 4-Phenyl-3-furoxancarbonitrile (Furoxan, RVC-589) | Able to activate the soluble guanylate cyclase by releasing Nitric Oxide under the action of thiol cofactors. Also inhibits platelet aggregation. Group: Biochemicals. Alternative Names: Furoxan, RVC-589. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-Methoxyindole-3-acetonitrile-d2 | 5-Methoxyindole-3-acetonitrile-d2 is a labelled analogue of 5-Methoxyindole-3-acetonitrile (M262818), which is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors. 5-Methoxyindole-3-acetonitrile-d2 is also an intermediate in synthesizing Melatonin-d4 (M215002), a hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation / metastasis of breast cancer cells by inhibiting estrogen receptor action. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C11H8D2N2O. US Biological Life Sciences. | Worldwide |
| 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride | 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride is a synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4). Applications: A synthetic reduced pterin cofactor. Group: Coenzymes. Synonyms: DMPH4; 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine. CAS No. 945-43-7. Purity: ≥95%. Mole weight: 231.68. Appearance: Powder. Form: Solid. DMPH4; 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine; 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride; 945-43-7. Cat No: COEC-094. | |
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