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Nogalamycin An unusual anthracycline produced by streptomyces nogalater var. Nogalater. It is a potent antibacterial and antitumor agent that interacts with DNA by intercalation. Synonyms: U 15167; Antibiotic U 15167; Nogalamicina; Nogalamycinum. Grades: >95% by HPLC. CAS No. 1404-15-5. Molecular formula: C39H49NO16. Mole weight: 787.80. BOC Sciences 5
Nogalamycin Nogalamycin is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1404-15-5. Pack Sizes: 1 mg. Product ID: HY-105846. MedChemExpress MCE
Nogalamycin Nogalamycin is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: antibiotic205t3; nogalomycin; NOGALAMYCIN; NOGALAMYCIN,STREPTOMYCES NOGALATER. Product Category: Inhibitors. Appearance: Solid. CAS No. 1404-15-5. Molecular formula: C39H53NO16. Mole weight: 787.8. Purity: 0.96. IUPACName: nogalamycin. Canonical SMILES: CC1C(C(C(C(O1)OC2CC(C(C3=C2C(=C4C(=C3)C(=O)C5=C6C(=CC(=C5C4=O)O)C7(C(C(C(C(O6)O7)O)N(C)C)O)C)O)C(=O)OC)(C)O)OC)(C)OC)OC. Density: 1.49g/cm³. Product ID: ACM1404155. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
deoxynogalonate monooxygenase The enzyme, characterized from the bacterium Streptomyces nogalater, is involved in the biosynthesis of the aromatic polyketide nogalamycin. Group: Enzymes. Synonyms: SnoaB (gene name); 12-deoxynogalonic acid oxidoreductase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate oxidase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate monooxygenase; deoxynogalonate oxidoreductase. Enzyme Commission Number: EC 1.13.12.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0615; deoxynogalonate monooxygenase; EC 1.13.12.22; SnoaB (gene name); 12-deoxynogalonic acid oxidoreductase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate oxidase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate monooxygenase; deoxynogalonate oxidoreductase. Cat No: EXWM-0615. Creative Enzymes
nogalonic acid methyl ester cyclase The enzyme, characterized from the bacterium Streptomyces nogalater, is involved in the biosynthesis of the aromatic polyketide nogalamycin. Group: Enzymes. Synonyms: methyl nogalonate cyclase; SnoaL (gene name); methyl nogalonate lyase (cyclizing). Enzyme Commission Number: EC 5.5.1.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5627; nogalonic acid methyl ester cyclase; EC 5.5.1.26; methyl nogalonate cyclase; SnoaL (gene name); methyl nogalonate lyase (cyclizing). Cat No: EXWM-5627. Creative Enzymes
Steffimycin B (Antibiotic U 40615) Steffimycin B is a anthracycline metabolite isolated from a Streptomyces sp. displaying antibacterial and antineoplastic properties. Binding to DNA, crystallographic studies suggest that it has a higher CpG base sequence specificity over the TpA step, similar to that of daunorubicin and nogalamycin. A close analogue was shown to be active against ras oncogene-expressed cells. Group: Biochemicals. Alternative Names: Antibiotic U 40615. Grades: Highly Purified. CAS No. 54526-94-2. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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