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| Product | Description | |
|---|---|---|
| Nonactin | Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K + , and NH 4 + , and it can also inhibit the surface expression of endogenous HSP60. In addition, Nonactin can induce apoptosis in β-catenin mutant tumor cells and has anti-tumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ammonium ionophore I. CAS No. 6833-84-7. Pack Sizes: 5 mg. Product ID: HY-N6790. |  |
| Nonactin | Nonactin is the smallest member of the macrotetrolide complex produced by a range of Streptomyces species. Originally the name, nonactin, reflected the lack of biological activity. The literature is somewhat confusing in this respect, as virtually all sources of nonactin are contaminated with small amounts of the much more active monactin. The BioAustralis nonactin has been purifed to remove traces of other biologically-active macrotetrolides. Like the other macrotetrolides, nonactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Group: Biochemicals. Grades: Highly Purified. CAS No. 6833-84-7. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Nonactin | The smallest member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium. It is resistant to gram-positive bacteria, mycobacteria and fungi, and it also inhibits L cells. Synonyms: Werramycin-A; NSC 52141; BRN 0076434; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo(32.2.1.17, 10.116, 19.125, 28)tetracontane-3, 12, 21, 30-tetrone, 2,5,11,14,20,23,29,32-octamethyl-(8CI). Grades: >99% by HPLC. CAS No. 6833-84-7. Molecular formula: C40H64O12. Mole weight: 736.93. |  |
| Monactin (5-demethyl-5-ethylnonactin, Antibiotic AKD 1B) | Monactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. Unlike nonactin, monactin has not previously been available for intensive investigation. Early literature reported that the related dinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Monactin inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Group: Biochemicals. Alternative Names: 5-demethyl-5-ethylnonactin, Antibiotic AKD 1B. Grades: Highly Purified. CAS No. 7182-54-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ammonium ionophore I | function tested, ?95.0% (Nonactin, HPLC). Group: Ionophores potentiometric for ise. |  |
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