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| Product | Description | |
|---|---|---|
| Nordihydroguaiaretic acid | 5g Pack Size. Group: Biochemicals, Building Blocks, Research Organics & Inorganics. Formula: C18H22O4. CAS No. 500-38-9. Prepack ID 14957191-5g. Molecular Weight 302.36. See USA prepack pricing. |  |
| Nordihydroguaiaretic acid | Herbal Medicinal Products Standards. Uses: For analytical and research use. Group: Reagents. CAS No. 500-38-9. Pack Sizes: 50MG. |  |
| Nordihydroguaiaretic acid | NDGA (Nordihydroguaiaretic acid), also known as masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. This agent may induce apoptosis in susceptible tumor cell populations as a result of disruption of the actin cytoskeleton in association with the activation of stress activated protein kinases (SAPKs). In addition, NDGA inhibits arachidonic acid 5-lipoxygenase (5LOX), resulting in diminished synthesis of inflammatory mediators such as prostaglandins and leukotrines; it may prevent leukocyte infiltration into tissues and the release of reactive oxygen species and, at higher concentrations, may also inhibit cyclooxygenase. Synonyms: 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol. Grades: > 98 %. CAS No. 500-38-9. Molecular formula: C18H22O4. Mole weight: 302.36. |  |
| Nordihydroguaiaretic acid | Nordihydroguaiaretic acid is a 5-lipoxygenase ( 5LOX ) ( IC 50 =8 μM) and tyrosine kinase inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: NDGA. CAS No. 500-38-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-N0198. |  |
| Nordihydroguaiaretic Acid | Fluorescence/Luminescence Spectroscopy; Food Additives, Flavours & Adulterants. Uses: For analytical and research use. Group: Reagents. Alternative Names: Butane, 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethyl-, 4-[4-(3,4-Dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, Dinorguaiaretic acid, dihydro-, 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol], β,γ-Dimethyl-α,δ-bis(3,4-dihydroxyphenyl)butane, NDGA, Dihydronorguaiaretic acid, 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane,1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di- (8CI), 4, 4'- (2, 3-Dimethyltetramethylene) dipyrocatechol, Nordihydroguaiaretic acid, NSC 4291, Norguaiaretic acid, dihydro-, 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(pyrocatechol). CAS No. 500-38-9. Pack Sizes: 500MG, 1G, 5G. IUPAC Name: 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol. | |
| Nordihydroguaiaretic acid 99+% (HPLC) | Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure. Inhibitor of broad bean lipoxygenase. The oxidation product from Resveratrol showed a high inhibitory activity, whereas Resveratrol itself had no activity and its oxidation efficiency was low. Group: Biochemicals. Alternative Names: 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis-1,2-benzenediol; 4, 4'- (2, 3-Di methyl tetra methyl ene) dipyrocatechol; Dihydronorguaiaretic Acid; NDGA; NSC 4291; Nordihydroguaiaretic Acid; β , γ -Dimethyl-α , δ -bis (3, 4-dihydroxyphenyl) butane. Grades: Reagent Grade. CAS No. 500-38-9. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. |  Worldwide |
| Masoprocol | Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: meso-Nordihydroguaiaretic acid; meso-NDGA. CAS No. 27686-84-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109500. | |
| Nordihydro Guaiaretic Acid-[d6] | Nordihydro Guaiaretic Acid-[d6], is the labelled analogue of Nordihydro Guaiaretic Acid. Nordihydroguaiaretic acid(NDGA), also known as masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. Synonyms: Nordihydro Guaiaretic Acid D6. CAS No. 1346600-58-5. Molecular formula: C18H16D6O4. Mole weight: 308.4. | |
| Terameprocol | Terameprocol, a semi-synthetic tetra-methylated derivative of nordihydroguaiaretic acid (NDGA) and transcriptional inhibitor with potential antiviral, antiangiogenic, and antineoplastic activities. Terameprocol competes with the transcription factor Sp1 for specific Sp1 DNA binding domains within gene promoter regions during DNA synthesis. In virally-infected cells, blocking of the Sp1 binding site suppresses Sp1-regulated viral promoter activity and gene expression, thereby inhibiting viral transcription and replication. In tumor cells, blockage of Sp1 binding sites by this agent interferes with the transcription of the Sp1-dependant genes cyclin-dependant kinase (Cdc2), survivin, and vascular endothelial growth factor (VEGF), which are overexpressed in a variety of cancers. By suppressing Sp1-regulated transcription of these genes, terameprocol may reduce tumor angiogenesis and tumor cell proliferation and induce tumor cell apoptosis. Synonyms: meso-Tetra-O-methylnordihydroguaiaretic acid; EM-1421; EM1421; EM 1421; rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(1,2-dimethoxybenzene); TMNDGA. Grades: >98%. CAS No. 24150-24-1. Molecular formula: C22H30O4. Mole weight: 358.47. | |
| Terameprocol | Terameprocol is a synthetic derivative of Nordihydroguaiaretic acid and a non-selective lipoxygenase inhibitor. Terameprocol has antiviral and antitumor effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EM-1421. CAS No. 24150-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10447. | |
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