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| Product | Description | |
|---|---|---|
| NSC 95397 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| NSC 95397 | NSC 95397. Group: Biochemicals. Grades: Purified. CAS No. 93718-83-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| NSC 95397 | NSC 95397 is a 1,4-naphthoquinone-based irreversible inhibitor of Cdc25 dual-specificity phosphatases (Ki = 32, 96 and 40 nM for inhibition of Cdc25A, -B and -C respectively). NSC 95397 exhibits 125-180-fold selectivity over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. Synonyms: 2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone; NSC-95397; NSC95397; NSC 95397. Grades: ≥97% by HPLC. CAS No. 93718-83-3. Molecular formula: C14H14O4S2. Mole weight: 310.38. |  |
| Cdc25 Inhibitor IV, NSC 95397 (2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, PTP Inhibitor XXIX) | A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki=32nM, 96nM, and 40nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50=1.8uM). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments. Group: Biochemicals. Grades: Highly Purified. CAS No. 93718-83-3. Pack Sizes: 10mg. Molecular Formula: C??H??O?S?, Molecular Weight: 310.4. US Biological Life Sciences. | Worldwide |
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