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O-Methylviridicatin O-Methylviridicatin is a metabolite produced by several species of Penicillium. It blocks TNF-alpha activation of the HIV LTR in the Hela-based system, with an IC50 of 5 mM, and inhibits virus production in the OM-10.1 cell line, a model of chronic infection responsive to induction by TNF-alpha, with an IC50 of 2.5 mM. Synonyms: 3-methoxy-4-phenyl-Carbostyril; Viridicatin methyl ester; 3-O-Methylviridicatin; O-methylviridicatin; 3-methoxy-4-phenylquinolin-2(1h)-one; 3-Methoxyviridicatin. Grades: ≥99%. CAS No. 6152-57-4. Molecular formula: C16H13NO2. Mole weight: 251.28. BOC Sciences 5
O-Methylviridicatin (AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one) 3-O-Methylviridicatin is a metabolite produced by several species in the genus, Penicillium. Recently, 3-O-methylviridicatin was demonstrated to be a strong inhibitor of the tumor necrosis factor alpha (TNF)-induced replication of human immunodeficiency virus (HIV). Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite. Group: Biochemicals. Alternative Names: AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one. Grades: Highly Purified. CAS No. 6152-51-4. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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