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| Product | Description | |
|---|---|---|
| o6-Benzylguanine | O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 19916-73-5. Molecular formula: C12H11N5O. Mole weight: 241.25. Purity: 0.97. Canonical SMILES: NC(N=C1OCC2=CC=CC=C2)=NC3=C1NC=N3. Product ID: ACM19916735. Alfa Chemistry ISO 9001:2015 Certified. |  |
| O6-Benzylguanine | ?98% (TLC), solid. Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. Alternative Names: O6-Benzylguanine, 2-Amino-6-(phenylmethoxy)-9H-purine, 1H-Purin-2-amine, 6-(phenylmethoxy)- (9CI), Purine, 2-amino-6-(benzyloxy)- (7CI,8CI), 6-O-Benzylguanine,6-(Phenylmethoxy)-9H-purin-2-amine, NSC 637037, 6-(Benzyloxy)guanine, 2-Amino-6-(benzyloxy)purine, O6-Benzylguanine. |  |
| O6-Benzylguanine | An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| O6-Benzylguanine | O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19916-73-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W002585. |  |
| O6-Benzylguanine | O6-Benzylguanine is a guanine derivative that acts as an irreversible inhibitor of O6-Alkylguanine-DNA alkyltransferase (AGT; MGMT), a DNA repair protein. It inactivates AGT and increases the chemotherapeutic effectiveness of chloroethylating and methylating agents in vitro and in human tumor xenograft models. Uses: An irreversible inhibitor of the mammalian dna repair protein, o6-alkylguanine-dna alkyltransferase. assists in the protection against carcinogenic and therapeutic alkylating agents. Synonyms: 6-phenylmethoxy-7H-purin-2-amine; 6-phenylmethoxy-7H-purin-2-amine. Grades: ≥ 98 %. CAS No. 19916-73-5. Molecular formula: C12H11N5O. Mole weight: 241.25. |  |
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