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Odanacatib Odanacatib, also known as MK-0822, is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption. Uses: For research used only. Synonyms: MK0822; MK-0822; MK 0822; Odanacatib. Grades: >98%. CAS No. 603139-19-1. Molecular formula: C25H27F4N3O3S. Mole weight: 525.56. BOC Sciences 9
Odanacatib Odanacatib (MK-0822) is a potent and selective inhibitor of cathepsin K , with an IC 50 of 0.2 nM for human cathepsin K. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0822. CAS No. 603139-19-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10042. MedChemExpress MCE
MK-0822 MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption. Group: Biochemicals. Alternative Names: N- (1-cyanocyclopropyl) -4-fluoro-N2-{ (1S) -2, 2, 2-trifluoro-1-[4'- (methylsulfonyl) biphenyl-4-yl]ethyl}-L-leucinamide, Odanacatib. Grades: Highly Purified. CAS No. 603139-19-1. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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