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An impurity of Olaparib, which selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks. Synonyms: 4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one. Grades: > 95%. Molecular formula: C24H24N4O3. Mole weight: 416.48.
Olaparib Impurity 2
An impurity of Olaparib, which selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks. Synonyms: 6-chloro-4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one. Grades: > 95%. Molecular formula: C24H22ClFN4O3. Mole weight: 468.92.
Olaparib Impurity 4
Olaparib Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1021298-68-9. Molecular formula: C16H10FN3O. Mole weight: 279.27. Catalog: APB1021298689.
Olaparib Impurity 5
Olaparib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16859-59-9. Molecular formula: C8H6O3. Mole weight: 150.13. Catalog: APB16859599.
Olaparib Impurity 66
Olaparib Impurity 66. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1090982-59-4. Molecular formula: C10H16N2O2. Mole weight: 196.25. Catalog: APB1090982594.
2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 2-fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylmethyl)benzoic acid; 5-[(3,4-Dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoic Acid. CAS No. 763114-26-7. Molecular formula: C16H11FN2O3. Mole weight: 298.27.
3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 3-[(4-Oxo-3,4-dihydro-1-phthalazinyl)methyl]benzoic acid. CAS No. 420846-72-6. Molecular formula: C16H12N2O3. Mole weight: 280.28.
3-hydroxyisobenzofuran-1(3H)-one
3-hydroxyisobenzofuran-1(3H)-one is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 3-hydroxyisobenzofuran-1(3H)-one; 16859-59-9; o-Phthalaldehydic acid; hydroxyphthalide; CHEBI:495639; MFCD00956142; 3-Hydroxyphthalide; 1(3H)-isobenzofuranone, 3-hydroxy-; 3-hydroxy-3H-2-benzofuran-1-one; SCHEMBL228037; CHEMBL234051; SCHEMBL18705376; AMY7661; JKNKNWJNCOJPLI-UHFFFAOYSA-N; 3-hydroxy-3H-isobenzofuran-1-one; 3-Hydroxybenzo[c]furan-1(3H)-one; 3-hydroxy-2-benzofuran-1(3H)-one; AKOS022504694; DS-19761; SY270554; 3-hydroxy-1,3-dihydro-2-benzofuran-1-one; CS-0143440; FT-0771570; H1754; D71106; Q27105161. CAS No. 16859-59-9. Molecular formula: C8H6O3. Mole weight: 150.13.
4-(3-(4-butyrylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4-{3-[(4-Butyryl-1-piperazinyl)carbonyl]-4-fluorobenzyl}-1(2H)-phthalazinone. CAS No. 2250243-17-3. Molecular formula: C24H25FN4O3. Mole weight: 436.48.
4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-benzoyl]piperazine. CAS No. 763113-06-0. Molecular formula: C24H24N4O3. Mole weight: 416.47.
4-(4-fluoro-3-(4-(2-fluoro-4-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4,4'-{1,4-Piperazinediylbis[carbonyl(4-fluoro-3,1-phenylene)methylene]}di(1(2H)-phthalazinone). CAS No. 2250242-62-5. Molecular formula: C36H28F2N6O4. Mole weight: 646.64.
piperazine-1,4-diylbis(cyclopropylmethanone)
piperazine-1,4-diylbis(cyclopropylmethanone) is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 1, 4-Piperazinediylbis (cyclopropylmethanone). CAS No. 458535-34-7. Molecular formula: C12H18N2O2. Mole weight: 222.28.
tert-butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4-Cyclopropanoylpiperazine-1-carboxylic Acid tert-Butyl Ester. CAS No. 414910-15-9. Molecular formula: C13H22N2O3. Mole weight: 254.33.
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