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| Product | Description | |
|---|---|---|
| Olcegepant | Olcegepant, also called as BIBN4096BS or BIBN 4096, is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor(IC50= 0.03 nM) and has been shown to block all effects of infused CGRP (2) and should ef. Synonyms: BIBN-4096; BIBN4096; BIBN 4096; BIBN-4096BS; BIBN4096BS; BIBN 4096BS; Olcegepant; N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide; Olcegepant; Olcegepant [INN]; BIBN-4096BS; BIBN 4096 BS; BIBN4096BS; CHEMBL2071; CHEMBL 2071; CHEMBL-2071. CAS No. 204697-65-4. Molecular formula: C38H47Br2N9O5. Mole weight: 869.65. |  |
| Olcegepant | Olcegepant is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist. Olcegepant displays high affinity for human CGRP receptors and exhibits no significant affinity for 75 other receptors. Olcegepant may a be viable option for the treatment of acute migraines. Group: Biochemicals. Alternative Names: 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)piperazine; N- [ (1R) -2- [ [ (1S) -5-Amino-1- [ [4- (4-pyridinyl) -1-piperazinyl] carbonyl] pentyl] amino] -1- [ (3, 5-dibromo-4-hydroxyphenyl) methyl] -2-oxoethyl] -4- (1, 4-dihydro-2-oxo-3 (2H) -quinazolinyl) -1-piperidinecarboxamide; BIBN 4096BS; BIBN 4096. Grades: Highly Purified. CAS No. 204697-65-4. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Olcegepant hydrochloride | Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with 150-fold selective over the peptidic antagonist CGRP8-37 (IC50 = 0.03 nM, Ki = 14.4 pM for human CGRP). Synonyms: N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide;hydrochloride; Olcegepant (hydrochloride); Olcegepant hydrochloride. CAS No. 586368-06-1. Molecular formula: C38H47Br2N9O5.HCl. Mole weight: 906.11. | |
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