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Olprinone (Loprinone) is a potent phosphodiesterase (PDE) 3 inhibitor, with IC 50 s of 150, 100, 0.35 and 14 μM for PDE1, PDE2, PDE3 and PDE4, respectively. Olprinone is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Loprinone. CAS No. 106730-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14254A.
Olprinone
Olprinone(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor. Uses: Cardiotonic agents. Synonyms: Olprinone; 106730-54-5; loprinone; Olprinone [INN]5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile. Grades: >98%. CAS No. 106730-54-5. Molecular formula: C14H10N4O. Mole weight: 250.26.
Olprinone is a selective phosphodiesterase 3 (PDE3) inhibitor. Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output after cardiopulmonary bypass (CPB). Olprinone was infused at a rate of 0.2 μg/kg/min when weaning from CPB was started. Olprinone has also shown potent antioxidative and anti-inflammatory effects in the meconium-induced oxidative lung injury. Synonyms: 1,2-Dihydro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride, Loprinone hydrochloride. Grades: >98%. CAS No. 119615-63-3. Molecular formula: C14H11ClN4O. Mole weight: 286.72.
Olprinone Hydrochloride
Olprinone (Loprinone) Hydrochloride is a potent phosphodiesterase (PDE) 3 inhibitor, with IC 50 s of 150, 100, 0.35 and 14 μM for PDE1, PDE2, PDE3 and PDE4, respectively. Olprinone Hydrochloride is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Loprinone Hydrochloride. CAS No. 119615-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14254.
Olprinone Impurity 1
Olprinone Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141354-29-2. Molecular formula: C12H10N4O. Mole weight: 226.24. Catalog: APB141354292.
Olprinone Impurity 3
Olprinone Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402751-73-8. Molecular formula: C14H11N3O3. Mole weight: 269.26. Catalog: APB1402751738.
Olprinone Impurity B
Olprinone Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide. CAS No. 106730-62-5. Molecular formula: C14H12N4O2. Mole weight: 268.27. Catalog: APB106730625.
Loprinone Hydrochloride
Inotropic agent which inhibits cAMP phosphodiesterase. Cardiotonic. Group: Biochemicals. Alternative Names: 1,2-Dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride; Olprinone Hydrochloride; Coretec; E 1020. Grades: Highly Purified. CAS No. 119615-63-3. Pack Sizes: 10mg. US Biological Life Sciences.
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