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| Product | Description | |
|---|---|---|
| Oprozomib | Oprozomib is the second class of proteasome inhibitors with higher specificities and reduced toxicities, against head and neck squamous cell carcinoma. Group: Biochemicals. Alternative Names: ONX 0912; PR 047; O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide. Grades: Highly Purified. CAS No. 935888-69-0. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
| Oprozomib | Oprozomibm, also known as ONX 0912 and PR 047, is an orally bioavailable proteasome inhibitor with potential antineoplastic activity. ONX 0912 inhibits the activity of the proteasome, thereby blocking the targeted proteolysis normally performed by the proteasome; this may result in an accumulation of unwanted or misfolded proteins. Disruption of various cell signaling pathways may follow, eventually leading to the induction of apoptosis and inhibition of tumor growth. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquitinated. Synonyms: ONX0912; ONX-0912; ONX 0912; PR047; PR-047; PR 047. Grades: >98%. CAS No. 935888-69-0. Molecular formula: C25H32N4O7S. Mole weight: 532.60918. |  |
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