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| Product | Description | |
|---|---|---|
| Orotidine | Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 314-50-1. Pack Sizes: 1 mg. Product ID: HY-113226. |  |
| Orotidine | Orotidine. Group: Biochemicals. Alternative Names: Uridine-6-carboxylic acid. Grades: Highly Purified. CAS No. 314-50-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C10H12N2O8. US Biological Life Sciences. |  Worldwide |
| Orotidine | Orotidine is a nucleoside metabolized from orotic acid. In humans, orotidine occurs as its 5'-phosphate (orotidylic acid), which is an intermediate in pyrimidine nucleotide biosynthesis (cytidine and uridine) that are found in nucleic acids. Synonyms: 6-Carboxyuridine; 3-Ribofuranosylorotic acid; Uridin-6-carboxylic acid. CAS No. 314-50-1. Molecular formula: C10H12N2O8. Mole weight: 288.21. |  |
| Orotidine 5?-monophosphate trisodium salt | ?99% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| Orotidine 5'-monophosphate trisodium salt | Orotidine 5'-monophosphate trisodium salt is a vital biomedical compound aiding in sdtuying pyrimidine metabolic disorders. Its multifaceted role as a precursor in the biosynthesis of crucial nucleotide uridine 5'-triphosphate is an indispensable component for RNA and DNA synthesis. Synonyms: Orotidylic acid; OMP; 3-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid,sodium; sodium 3- ( (2R, 3R, 4S, 5R) -3, 4-dihydroxy-5- (phosphonatooxymethyl) tetrahydrofuran-2-yl) -2, 6-dioxo-1, 2, 3, 6-tetrahydropyrimidine-4-carboxylate. CAS No. 68244-58-6. Molecular formula: C10H10N2O11PNa3. Mole weight: 434.14. | |
| Orotidine 5'-Monophosphate Trisodium Salt | Orotidine 5'-Monophosphate Trisodium Salt is synthesized from the reaction of silver salt with MeI and phosphorylated with the cyanoethyl phosphate-dicyclohexyl carbodiimide reagent. Group: Biochemicals. Grades: Highly Purified. CAS No. 68244-58-6. Pack Sizes: 1mg. Molecular Formula: C10H10N2Na3O11P, Molecular Weight: 434.14. US Biological Life Sciences. | Worldwide |
| orotidine-5'-phosphate decarboxylase | The enzyme from higher eukaryotes is identical with EC 2.4.2.10 orotate phosphoribosyltransferase. Group: Enzymes. Synonyms: orotidine-5'-monophosphate decarboxylase; orotodylate decarboxylase; orotidine phosphate decarboxylase; OMP decarboxylase; orotate monophosphate decarboxylase; orotidine monophosphate decarboxylase; orotidine phosphate decarboxylase; OMP-DC; orotate decarboxylase; orotidine 5'-phosphate decarboxylase; orotidylic decarboxylase; orotidylic acid decarboxylase; orotodylate decarboxylase; ODCase; orotic decarboxylase; orotidine-5'-phosphate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.23. CAS No. 9024-62-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4768; orotidine-5'-phosphate decarboxylase; EC 4.1.1.23; 9024-62-8; orotidine-5'-monophosphate decarboxylase; orotodylate decarboxylase; orotidine phosphate decarboxylase; OMP decarboxylase; orotate monophosphate decarboxylase; orotidine monophosphate decarboxylase; orotidine phosphate decarboxylase; OMP-DC; orotate decarboxylase; orotidine 5'-phosphate decarboxylase; orotidylic decarboxylase; orotidylic acid decarboxylase; orotodylate decarboxylase; ODCase; orotic decarboxylase; orotidine-5'-phosphate carboxy-lyase. Cat No: EXWM-4768. |  |
| Native Brewer's bottom yeast Orotidine-5'-monophosphate pyrophosphorylase | Orotate phosphoribosyltransferase (OPRTase) or Orotic acid phosphoribosyltransferase is an enzyme involved in pyrimidine biosynthesis. It catalyzes the formation of orotidine 5'-monophosphate (OMP) from orotate and phosphoribosyl pyrophosphate. In yeast and bacteria, orotate phosphoribosyltransferase is an independent enzyme with a unique gene coding for the protein, whereas in mammals and other multicellular organisms, the catalytic function is carried out by a domain of the bifunctional enzyme UMP synthase. Applications: This is the preferred enzyme for assaying orotidine 5?-monophosphate and for the production of omp analogs from the corresponding orot...ty: ~25 units/mg protein (modified Warburg-Christian). Storage: -20°C. Form: Lyophilized powder containing approx. 50% buffer salts. Source: Brewer's bottom yeast. orotidylic acid phosphorylase; orotidine-5'-phosphate pyrophosphorylase; OPRTase; orotate phosphoribosyl pyrophosphate transferase; orotic acid phosphoribosyltransferase; orotidine 5'-monophosphate pyrophosphorylase; orotidine monophosphate pyrophosphorylase; orotidine phosphoribosyltransferase; orotidylate phosphoribosyltransferase; orotidylate pyrophosphorylase; orotidylic acid pyrophosphorylase; orotidylic phosphorylase; orotidylic pyrophosphorylase; EC 2.4.2.10; 9030-25-5. Cat No: NATE-0498. | |
| 3-hexulose-6-phosphate synthase | Requires Mg2+ or Mn2+ for maximal activity. The enzyme is specific for D-ribulose 5-phosphate as substrate as ribose 5-phosphate, xylulose 5-phosphate, allulose 6-phosphate and fructose 6-phosphate cannot act as substrate. In addition to formaldehyde, the enzyme can also use glycolaldehyde and methylglyoxal. This enzyme, along with EC 5.3.1.27, 6-phospho-3-hexuloisomerase, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds. The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyses the reactions of this enzyme and EC 5.3.1.27, 6-phospho-3-hexuloisomerase. This enzyme is a member of the orotidine 5'-monophosphate decarboxylase (OMPDC) suprafamily. Group: Enzymes. Synonyms: D-arabino-3-hexulose 6-phosphate formaldehyde-lyase; 3-hexulosephosphate synthase; 3-hexulose phosphate synthase; HPS. Enzyme Commission Number: EC 4.1.2.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4879; 3-hexulose-6-phosphate synthase; EC 4.1.2.43; D-arabino-3-hexulose 6-phosphate formaldehyde-lyase; 3-hexulosephosphate synthase; 3-hexulose phosphate synthase; HPS. Cat No: EXWM-4879. | |
| 5-Fluoroorotic Acid Monohydrate (FOA, 5-FOA) | Useful in the identification and selection of the strains of Saccharomyces cerevisiae that contain the mutant ura3- gene. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5-phosphate decarboxylase and are therefore unable to grow on 5-FOA-containing media. Group: Biochemicals. Alternative Names: FOA; 5-FOA; 5-Fluoroorotate; 5-FLUORO-4-PYRIMIDINECARBOXYLIC ACID; 5-FLUORO-1,2,3,6-TETRAHYDRO-2,6-DIOXO-(9CI); 1,2,3,6-TETRAHYDRO-2,6-DIOXO-5-FLUORO-4- PYRIMIDINECARBOXYLIC ACID; 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid. Grades: Molecular Biology Grade. CAS No. 207291-81-4,220141-70-8,703-95-7. Pack Sizes: 500mg, 1g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Azaribine | Azaribine (2',3',5'-Tri-O-acetyl-6-azauridine) is a potent orotidine monophosphate decarboxylase (OMPD) inhibitor. Azaribine is an antiviral inhibitor of several RNA viruses and inhibits viral genome replication and gene transcription. Azaribine shows broad-spectrum antiviral activity ( EC 50 =3.80?nM-1.73?μM against influenza A and B viruses; EC 50 =1.62 μM against ZIKV Paraiba). Azaribine, a triacetate salt of Azauridine, has the potential for psoriasis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2',3',5'-Tri-O-acetyl-6-azauridine. CAS No. 2169-64-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1537. | |
| β-Pyrazofurin Trifluoroacetic Acid Salt | β-Pyrazofurin Trifluoroacetic Acid Salt is a remarkable antineoplastic compound, used for studying a myriad of malignancies encompassing leukemia, lymphoma and solid tumors. In its unparalleled mode of action, this extraordinary product stifles the catalytic endeavors of orotidine 5?-monophosphate decarboxylase, thereby instigating a disruptive cascade culminating in hindered RNA and DNA synthesis within the stricken neoplastic cells. Embodying a beacon of hope, it unveils an array of therapeutic possibilities for those afflicted by these insidious pathologies. Synonyms: 4-Hydroxy-3-β-D-ribofuranosyl-1H-pyrazole-5-carboxamide Trifluoroacetic Acid Salt; Antibiotic A 23813 Trifluoroacetic Acid Salt; NSC 143095 Trifluoroacetic Acid Salt; Pirazofurin Trifluoroacetic Acid Salt; Przf Trifluoroacetic Acid Salt; Pyrazofurin Trifluoroacetic Acid Salt; Pyrazomycin Trifluoroacetic Acid Salt; Pyrozofurin Trifluoroacetic Acid Salt; β-Pyrazomycin Trifluoroacetic Acid Salt. Molecular formula: C11H14F3N3O8. Mole weight: 373.24. | |
| orotate phosphoribosyltransferase | The enzyme from higher eukaryotes also catalyses the reaction listed as EC 4.1.1.23, orotidine-5'-phosphate decarboxylase. Group: Enzymes. Synonyms: orotidylic acid phosphorylase; orotidine-5'-phosphate pyrophosphorylase; OPRTase; orotate phosphoribosyl pyrophosphate transferase; orotic acid phosphoribosyltransferase; orotidine 5'-monophosphate pyrophosphorylase; orotidine monophosphate pyrophosphorylase; orotidine phosphoribosyltransferase; orotidylate phosphoribosyltransferase; orotidylate pyrophosphorylase; orotidylic acid pyrophosphorylase; orotidylic phosphorylase; orotidylic pyrophosphorylase. Enzyme Commission Number: EC 2.4.2.10. CAS No. 9030-25-5. OPRTase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2639; orotate phosphoribosyltransferase; EC 2.4.2.10; 9030-25-5; orotidylic acid phosphorylase; orotidine-5'-phosphate pyrophosphorylase; OPRTase; orotate phosphoribosyl pyrophosphate transferase; orotic acid phosphoribosyltransferase; orotidine 5'-monophosphate pyrophosphorylase; orotidine monophosphate pyrophosphorylase; orotidine phosphoribosyltransferase; orotidylate phosphoribosyltransferase; orotidylate pyrophosphorylase; orotidylic acid pyrophosphorylase; orotidylic phosphorylase; orotidylic pyrophosphorylase. Cat No: EXWM-2639. | |
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