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| Product | Description | |
|---|---|---|
| Orvepitant | Orvepitant is a potent and selective Neurokinin-1 (NK1) antagonist. It may be potential therapeutic for the treatment of patients with major depressive disorder (MDD), anxiety and insomnia. It was developed by GlaxoSmithKline and is in clinical phase 2 trials. Uses: Orvepitant may be potential therapeutic for the treatment of patients with major depressive disorder (mdd), anxiety and insomnia. Synonyms: (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide;Orvepitant; GW-823296; GW823296; GW 823296; GW823296X. Grades: 95%. CAS No. 579475-18-6. Molecular formula: C31H35F7N4O2. Mole weight: 628.63. |  |
| Orvepitant maleate | Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pK i of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW823296 maleate. CAS No. 579475-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122347A. |  |
| Orvepitant maleate | Orvepitant maleate is a neurokinin-1 (NK1) receptor antagonist developed for the treatment of depression and anxiety disease. Uses: Potential treatment of depression and anxiety disease. Synonyms: GW-823296B; GW823296B; GW 823296B; Orvepitant maleate; (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide (Z)-but-2-enedioic acid. Grades: 99%. CAS No. 579475-24-4. Molecular formula: C31H35F7N4O2.C4H4O4. Mole weight: 744.7. | |
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