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| Product | Description | |
|---|---|---|
| OSI-930 | OSI-930 is an orally selective inhibitor of Kit , KDR and CSF-1R (c-Fms) with IC 50 s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1 , c-Raf , Lck and low activity against PDGFRα/β , Flt-3 and Abl. OSI-930 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 728033-96-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10204. |  |
| OSI-930 | OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Uses: Designed for use in research and industrial production. Additional or Alternative Names: OSI-930; OSI 930; OSI930. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 728033-96-3. Molecular formula: C22H16F3N3O2S. Mole weight: 443.44. Purity: >98%. IUPACName: 3-((quinolin-4-ylmethyl)amino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide. Canonical SMILES: O=C(C1=C(NCC2=CC=NC3=CC=CC=C23)C=CS1)NC4=CC=C(OC(F)(F)F)C=C4. Product ID: ACM728033963. Alfa Chemistry ISO 9001:2015 Certified. Categories: OSI-906. |  |
| OSI-930 | OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Synonyms: OSI 930; OSI930. Grades: >98%. CAS No. 728033-96-3. Molecular formula: C22H16F3N3O2S. Mole weight: 443.444. |  |
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