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| Product | Description | |
|---|---|---|
| Osilodrostat | Osilodrostat, also called as LCI699, is a modulator of 11-β-hydroxylase (IC50 = 2.5 nM), useful for treating a disorder ameliorated 11-β-hydroxylase inhibition, and a potent inhibitor of aldosterone synthase (IC50 = 0.7 nM). Synonyms: 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile; LCI699. CAS No. 928134-65-0. Molecular formula: C13H10FN3. Mole weight: 227.24. |  |
| Osilodrostat | Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699. CAS No. 928134-65-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276. |  |
| Osilodrostat phosphate | Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699 phosphate. CAS No. 1315449-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276A. | |
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