Oxidoreductase Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
Superoxide oxidoreductase Quick inquiry Where to buy Suppliers range | Synonyms: ORGOTEIN; Superoxide dismutases; SOD. CAS No. 9054-89-1. | |
1,7-Dihydroxynaphthalene Quick inquiry Where to buy Suppliers range | The preparation of 1,7-Dihydroxynaphthalene and its prompt characterization from its NMR data and peculiarities. Removal of dihydroxynaphthalenes from aqueous solution with the aid of an oxidoreductase polyphenol oxidase and biopolymer chitosan. Group: Biochemicals. Grades: Highly Purified. CAS No. 575-38-2. Pack Sizes: 5g, 10g. Molecular Formula: C10H8O2, Molecular Weight: 160.169999999999. US Biological Life Sciences. | Worldwide |
2,3-Lutidine-N-oxide Quick inquiry Where to buy Suppliers range | 2,3-Lutidine-N-oxide can be used in biological study of enzymic reduction of pyridine- and nitropyridine-N-oxide derivs. by ferredoxin-NADP+ oxidoreductase and the role of their electron accepting potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 22710-07-2. Pack Sizes: 250mg, 1g. Molecular Formula: C7H9NO, Molecular Weight: 123.15. US Biological Life Sciences. | Worldwide |
2'-Hydroxy-3',4'-dimethylacetophenone Quick inquiry Where to buy Suppliers range | 2'-Hydroxy-3',4'-dimethylacetophenone is used for preparation of dicoumarol analogs as inhibitors of human NAD(P)H quinone oxidoreductase-1 (NQO1). Group: Biochemicals. Grades: Highly Purified. CAS No. 5384-55-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C10H12O2, Molecular Weight: 164.2. US Biological Life Sciences. | Worldwide |
2-(Methylthio)-4-pyridinecarboxylic Acid Quick inquiry Where to buy Suppliers range | 2-(Methylthio)-4-pyridinecarboxylic Acid was a useful reagent in preparation of 3-(3-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051, a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 74470-24-9. Pack Sizes: 50mg, 250mg. Molecular Formula: C7H7NO2S, Molecular Weight: 169.2. US Biological Life Sciences. | Worldwide |
2-Thenoyltri fluoroacetone Quick inquiry Where to buy Suppliers range | 2-Thenoyltri fluoroacetone is an inhibitor of respiration in animals and bacteria. TTFA binds at the quinone reduction site of succinate ubiquinone oxidoreductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 326-91-0. Pack Sizes: 10g, 25g. Molecular Formula: C8H5F3O2S, Molecular Weight: 222.18. US Biological Life Sciences. | Worldwide |
3Alpha-hydroxysteroid dehydrogenase Quick inquiry Where to buy Suppliers range | ammonium sulfate suspension. Group: Main Products. Alternative Names: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE;3ALPHA-HYDROXYSTEROID: NAD[P]+ OXIDOREDUCTASE;EC 1.1.1.50;EC: 1.1.1.50;3alpha-hydroxysteroid dehydrogenase F. pseu. test. ~9 U/mg;3alpha-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni;Dehydrogenase, 3alpha-hydroxy steroid;HYDROXYSTEROID OXIDOREDUCTASE. Grades: ≥50units/mg protein. CAS No. 9028-56-2. Mole weight: 0. | |
3-Bromo-5-phenyl salicylic acid Quick inquiry Where to buy Suppliers range | The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. 3-Bromo-5-phenyl salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM). Synonyms: NSC 109116; 3-bromo-2-hydroxy-5-phenylbenzoic acid. Grades: ≥95%. CAS No. 4906-68-7. Molecular formula: C13H9BrO3. Mole weight: 293.1. | |
5-Bromo-3-phenyl salicylic acid Quick inquiry Where to buy Suppliers range | The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. 5-Bromo-3-phenyl salicylic acid selectively inhibits AKR1C1 (Ki = 140 nM) over AKR1C2 (K1 = 1.97 μM) and AKR1C3 (Ki = 21 μM). Synonyms: 5-Bromo-2-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Grades: ≥98%. CAS No. 99514-99-5. Molecular formula: C13H9BrO3. Mole weight: 293.1. | |
Atpenin A5 Quick inquiry Where to buy Suppliers range | Antibiotic. Antifungal. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor. Mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Cardioprotective. Modulates mitochondrial ROS generation during cardioprotection.The IC50 value against bovine heart complex II is 3.6nM (which is ~300-fold lower than the IC50 value of carboxin (1.1uM)). It also inhibits fumarate reductase of Ascaris suum (IC50 = 12nM). Inhibition of E. coli succinate dehydrogenase is less potent (IC50 = 5uM). By co-crystallization studies of atpenin A5 and complex II, the binding site of atpenin A5 was found to be the quinone-binding site of complex II. Additionally, atpenin A5 has been shown to have a protective action against ischemia-reperfusion via the activation of mitochondrial KATP channels. Group: Biochemicals. Alternative Names: 3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone. Grades: Highly Purified. CAS No. 119509-24-9. Pack Sizes: 250ug, 1mg. Molecular Formula: C15H21Cl2NO5. US Biological Life Sciences. | Worldwide |
Atpenin A5 (3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone) Quick inquiry Where to buy Suppliers range | Synthetic. Originally isolated from Penicillium sp. strain. An antibiotic and antifungal agent. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor and mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Modulates mitochondrial ROS generation during cardioprotection. Group: Biochemicals. Grades: Highly Purified. CAS No. 119509-24-9. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
Atractyloside, Calcium Salt Quick inquiry Where to buy Suppliers range | Atractyloside Calcium Salt is a specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in permeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. Atractyloside induces the release of ahyaluronidase-induced murine WW domain-containing oxidoreductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity. Group: Biochemicals. Alternative Names: (2 β,15α)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo- β-D-glucopyranosyl]oxy]-19-Norkaur-16-en-18-oic Acid Calcium Salt; 19-Norkaur-16-en-18-oic acid deriv. 1H-2,10a-Ethanophenanthrene Calcium Salt. Grades: Highly Purified. CAS No. 772298-35-8 free acid. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
Aureothin (Distacin, Distacyne, Mycolutein, Antibiotic 74A'', Antibiotic JA 2814K) Quick inquiry Where to buy Suppliers range | Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. Aureothin acts by inhibition of oxidoreductase. More recently Aureothin has been shown to be a potent inhibitor of Helicobacter pylori. Group: Biochemicals. Alternative Names: Distacin, Distacyne, Mycolutein, Antibiotic 74A'', Antibiotic JA 2814K. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
Aureothin (Mycolutein, Distacin, JA 2814K, Antibiotic 74A, BRN 0058476) Quick inquiry Where to buy Suppliers range | Oxidoreductase inhibitor. Antitrypanosomal, antibacterial, antifungal, insecticidal and pesticidal. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
CATALASE Quick inquiry Where to buy Suppliers range | CATALASE. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: equilase;Catalase-Agarose;H2O2 oxidoreductase;Catalase from A. niger, lyophil.;Catalase from bovine liver, lyophil.;Catalase-peroxidase;CATALASE FROM BOVINE LIVERCA.65000 U/MG PROTEIN SUSPENSION;CATALASE FROM ASPERGILLUSNIGER CA.2000 U/MG LYOPH.SALT-FREE. CAS No. 9001-5-2. Pack Sizes: 1 kg. Product ID: CDF4-0037. | |
Catalase from bovine liver Quick inquiry Where to buy Suppliers range | Catalase from bovine liver. Uses: Used for research and manufacturing. Group: Cosmetic Ingredients. Alternative Names: H2O2:H2O2 oxidoreductase. CAS No. 9001-5-2. Product ID: CDC10-0039. | |
Chloranilic Acid Quick inquiry Where to buy Suppliers range | A benzoquinone derivative that inhibits camel lens ?-crystallin/NADPH: quinone oxidoreductase activity. Potential antibacterial activities against methicillin-resistant Staphylococcus aureus. Group: Biochemicals. Alternative Names: 2,5-Dichloro-3,6-dihydroxy-2,5-Cyclohexadiene-1,4-dione;2,5-Dichloro-3,6-dihydroxy-p-benzoquinone; 2,5-Dihydroxy-3,6-dichloro-1,4-benzoquinone; NSC 6108; NSC 97383. Grades: Highly Purified. CAS No. 87-88-7. Pack Sizes: 1g, 10g. US Biological Life Sciences. | Worldwide |
Cholesterol oxidase Quick inquiry Where to buy Suppliers range | Cholesterol oxidase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: EC 1.1.3.6;EC: 1.1.3.6;CHOLESTEROL OXIDASE;CHOLESTEROL OXIDASE MICROBIAL;CHOLESTEROL OXIDASE, NOCARDIA SPECIES;CHOLESTEROL: OXYGEN OXIDOREDUCTASE;CHOLESTEROL: OXYGEN OXIDOREDUCTASE MICROBIAL;cholesterol oxidase F. pseudomonas sp. CAS No. 9028-76-6. Product ID: CDF4-0046. | |
D-3-HYDROXYBUTYRATE DEHYDROGENASE Quick inquiry Where to buy Suppliers range | D-3-HYDROXYBUTYRATE DEHYDROGENASE. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: D-3-HYDROXYBUTYRATE: NAD OXIDOREDUCTASE;BETA-HYDROXYBUTYRATE DEHYDROGENASE;BETA-HYDROXYBUTYRATE DEHYDROGENASE TYPE V;3-HBDH;3-HYDROXYBUTYRATE DEHYDROGENASE;(R)-3-HYDROXYBUTANOATE: NAD+ OXIDOREDUCTASE;[R]-3-HYDROXYBUTANOATE: NAD+ OXIDOREDUCTASE TYPE V;B-HYDROXYBUTYRATE DEHYDROGENASE TYPE IV FROM PSEUDO. CAS No. 9028-38-0. Pack Sizes: 1 kg. Product ID: CDF4-0049. | |
Diamine Oxidase from porcine kidney Quick inquiry Where to buy Suppliers range | Synonyms: Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing). CAS No. 9001-53-0. | |
Diaphorase Quick inquiry Where to buy Suppliers range | Diaphorase. Group: Heterocyclic Organic Compound. Alternative Names: QUINONE REDUCTASE;QUINONE REDUCTASE HUMAN;NADH: DYE OXIDOREDUCTASE;NAD(P)H: ACCEPTOR OXIDOREDUCTASE;NADH: LIPOAMIDE OXIDOREDUCTASE;NADH: LIPOAMIDE OXIDOREDUCTASE TYPE III;DTD;DTD HUMAN. CAS No. 9001-68-7. | |
Diminutol Quick inquiry Where to buy Suppliers range | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1, to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization. Synonyms: NG72; Diminisher of microtubule; CTK8F0853. Grades: ≥98%. CAS No. 361431-33-6. Molecular formula: C19H26N6OS. Mole weight: 386.5. | |
Ec 1.1.1.22 Quick inquiry Where to buy Suppliers range | lyophilized powder. Group: Heterocyclic Organic Compound. Alternative Names: EC 1.1.1.22;URIDINE-5-DIPHOSPHOGLUCOSE DEHYDROGENASE TYPE VI;UDP-GLUCOSE DEHYDROGENASE;UDP-GLUCOSE DEHYDROGENASE, E COLI;UDP-GLUCOSE:NAD+ 6-OXIDOREDUCTASE;UDP-Glucose Dehydrogenase, E.coli, Recombinant, E. coli;uridine diphosphoglucose dehydrogenase;uridine-5-diphosphoglucose*dehydrogenase type ii. CAS No. 9028-26-6. Mole weight: 0. | |
EC 1.1.1.37 Quick inquiry Where to buy Suppliers range | EC 1.1.1.37. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: (S)-MALATE : NAD+ OXIDOREDUCTASE;MDH;MDH MITOCHONDRIAL;MALATE DEHYDROGENASE;MALATE DEHYDROGENASE, HUMAN HEART, CYTOPLASMA;MALATE DEHYDROGENASE, HUMAN HEART, MITOCHONDRIA;MALATE DEHYDROGENASE MITOCHONDRIAL;MALATE DEHYDROGENASE PORCINE HEART. CAS No. 9001-64-3. Pack Sizes: 1 kg. Product ID: CDF4-0044. | |
Ec 1.1.1.47 Quick inquiry Where to buy Suppliers range | powder. Group: Heterocyclic Organic Compound. Alternative Names: BETA-D-GLUCOSE: NADP+ 1-OXIDOREDUCTASE;GLUCOSE DEHYDROGENASE;GLUCOSE DEHYDROGENASE, NADP DEPENDENT;GDH;EC 1.1.1.47;EC 1.1.1.119;D-GLUCOSE DEHYDROGENASE BM;D-GLUCOSE DEHYDROGENASE BS. CAS No. 9028-53-9. Molecular formula: NULL. Mole weight: 0. Safty Description: 26-36. Hazard statements: Xi. | |
EC 1.1.1.47 Quick inquiry Where to buy Suppliers range | EC 1.1.1.47. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: glucose dehydrogenase F. bacillus mega-terium;Dehydrogenase, glucose;GLUCOSE DEHYDROGENASE THERMOPLASMA,*ACID OPHILUM REC;BETA-D-GLUCOSE: NADP+ 1-OXIDOREDUCTASE;GLUCOSE DEHYDROGENASE;GLUCOSE DEHYDROGENASE, NADP DEPENDENT;GDH;EC 1.1.1.47. CAS No. 9028-53-9. Product ID: CDF4-0056. | |
(E)-Pterulinic acid Quick inquiry Where to buy Suppliers range | (E)-Pterulinic acid is a Coenzyme I: Coenzyme Q oxidoreductase inhibitor produced by Pterula sp. 82168. It has anti-yeast and filamentous fungus effect and has cytotoxic activity. Synonyms: ME-82168-N; Pterulinic acid. CAS No. 190143-30-7. Molecular formula: C15H11ClO4. Mole weight: 290.70. | |
Glucose oxidase Quick inquiry Where to buy Suppliers range | Glucose oxidase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: notatin;oxidaseglucose;1.1.3.4;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE II;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE II-S;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE VII;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE X-S. CAS No. 9001-37-0. Pack Sizes: 1 kg. Product ID: CDF4-0031. | |
GLUTATHIONE PEROXIDASE Quick inquiry Where to buy Suppliers range | Synonyms: GLUTATHIONE: HYDROGEN-PEROXIDE OXIDOREDUCTASE; GLUTATHIONE PEROXIDASE; GSH-PX; EC 1.11.1.9; glutathione peroxidase F. bov. erythro-cytes; Glutathione Peroxidase from bovine erythrocytes; Peroxidase, glutathione; GLUTATHIONE PEROXIDASE F. BOV. ERYTHRO-C YTES, ~1. CAS No. 9013-66-5. | |
Harzianopyridone Quick inquiry Where to buy Suppliers range | Harzianopyridone is a metabolite of Trichoderma harzianum that exhibits antifungal and antibacterial properties. Harzianopyridone acts as an atpenin-like inhibitor of mammalian and nematode mitochondrial complex II (succinate:ubiquinone oxidoreductase; SQR) with IC50 values of 0.017, 0.2, and 2 μM for bovine, rat, and nematode complex II, respectively. It also inhibits nematode quinol-fumarate reductase (QFR; IC50 = 0.36 μM). Synonyms: (-)-Harzianopyridone; 4-Hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexenyl]-2(1H)-pyridinone; 2(1H)-Pyridinone, 4-hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexen-1-yl]-; 2(1H)-Pyridinone, 4-hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexenyl]-; 4-Hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexen-1-yl]-2(1H)-pyridinone; (S,E)-4-hydroxy-5,6-dimethoxy-3-(2-methylhex-4-enoyl)pyridin-2(1H)-one. Grades: ≥95%. CAS No. 137813-88-8. Molecular formula: C14H19NO5. Mole weight: 281.30. | |
IACS-010759 Quick inquiry Where to buy Suppliers range | IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells. Synonyms: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole. Grades: ≥98%. CAS No. 1570496-34-2. Molecular formula: C25H25F3N6O4S. Mole weight: 562.57. | |
Laccase Quick inquiry Where to buy Suppliers range | Laccase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: Denilase ii s;Novozyme 809;p-Diphenol oxidase;Sp 504;Urushiol oxidase;Laccase from Rhus vernicifera,Benzenediol:oxygen oxidoreductase;Laccase, from Trametes versicolor, >=0.5units/mg;LACCASE FROM TRAMETES SPEC., 0.8+ UMG POWDER. CAS No. 80498-15-3. Pack Sizes: 1 kg. Product ID: CDF4-0053. | |
L-Glutamate oxidase Quick inquiry Where to buy Suppliers range | lyophilized powder. Group: Heterocyclic Organic Compound. Alternative Names: EC 1.4.3.11;L-GLUTAMATE OXIDASE;L-GLUTAMATE: OXYGEN OXIDO-REDUCTASE[DEAMINATING];L-GLUTAMATE OXIDASE FROM*STREPTOMYCES SP;L-Glutamate Oxidase from Streptomyces sp.,L-Glutamate:oxygen oxidoreductase (deaminating). CAS No. 39346-34-4. Molecular formula: NULL. Mole weight: 0. | |
Piericidin A Quick inquiry Where to buy Suppliers range | Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity. Synonyms: Shaoguanmycin B. Grades: >95.0%. CAS No. 2738-64-9. Molecular formula: C25H37NO4. Mole weight: 415.57. | |
Piericidin A (Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1) Quick inquiry Where to buy Suppliers range | Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces sp. It is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUOD-NUOB interface. Group: Biochemicals. Alternative Names: Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1. Grades: Highly Purified. CAS No. 2738-64-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Pterulone Quick inquiry Where to buy Suppliers range | Pterulone is a Coenzyme I: Coenzyme Q oxidoreductase inhibitor produced by Pterula sp. 82168. It has anti-yeast and filamentous fungus effect. Synonyms: (E)-Pterulone; Pterulone A. Grades: 95%. CAS No. 190143-31-8. Molecular formula: C13H11ClO2. Mole weight: 234.68. | |
RH1 Quick inquiry Where to buy Suppliers range | RH1 is a new bioreductive agent that is an excellent substrate for the two-electron reducing enzyme, NAD(P)H quinone oxidoreductase 1 (NQO1). In phase trials, RH1 was well tolerated with predictable and manageable toxicity. The MTD of 1430 μg/m(2)/day is the dose recommended for phase II trials. The biomarkers of DNA cross linking, DTD activity and NQO1 status have been validated and clinically developed. Synonyms: RH 1; RH-1; NSC697726; 2,5-di(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione. CAS No. 221635-42-3. Molecular formula: C12H14N2O3. Mole weight: 234.25. | |
Riboflavin-5-Phosphate Disodium Salt (Flavin mononucleotide, FMN) Quick inquiry Where to buy Suppliers range | Flavin mononucleotide (FMN), or riboflavin-5?-phosphate, is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as prosthetic group of various oxidoreductases including NADH dehydrogenase as well as cofactor in biological blue-light photo receptors. During the catalytic cycle, a reversible interconversion of the oxidized (FMN), semiquinone (FMNH ) and reduced (FMNH2) forms occurs in the various oxidoreductases. FMN is a stronger oxidizing agent than NAD and is particularly useful because it can take part in both one- and two-electron transfers. In its role as blue-light photo receptor, (oxidized) FMN stands out from the 'conventional' photo receptors as the signaling state and not an E/Z isomerization. Group: Biochemicals. Alternative Names: Flavin mononucleotide disodium salt; FMN. Grades: Purified. CAS No. 130-40-5. Pack Sizes: 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
Rotenone Quick inquiry Where to buy Suppliers range | Rotenone is a botanical insecticide that occurs naturally in seeds and stems of several plants. Rotenone is a mitochondrial electron transport inhibitor, inhibiting NADH/DB oxidoreductase and NADH oxidase with IC50 values of 28.8 and 5.1 nM, respectively. Synonyms: Rotenone; NSC 26258; NSC-26258; NSC26258; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: ≥95% by HPLC. CAS No. 83-79-4. Molecular formula: C23H22O6. Mole weight: 394.42. | |
RTA-408 Quick inquiry Where to buy Suppliers range | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Synonyms: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. Grades: >98%. CAS No. 1474034-05-3. Molecular formula: C33H44F2N2O3. Mole weight: 554.723. | |
Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin, Valacidin, Antibiotic RP 5278) Quick inquiry Where to buy Suppliers range | Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an important role in free radical production through redox cycling of NAD(P)H:quinone oxidoreductase (NQO1). Streptonigrin from Streptomyces flocculus is an aminoquinone antitumor antibiotic. Its antineoplastic activity requires reductive activation by Xanthine-converting enzymes. It induces apoptosis by a mechanism involving NF-κB. DNA cleavage reaction and chromosome damage by Streptonigrin are influenced by the nature of the metal ion present and dependent on the production of free radicals. Its antibiotic activity is iron-activated. Group: Biochemicals. Alternative Names: EC Number 223-501-8; 5278RP; AO 50165L302; Abbott Crystalline antibiotic; Bruneomycin; NSC 45383; NSC 56748; NSC 83950; Nigrin; Rufocromomycin; SN; STP; Streptonigran; Streptonigrin; 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic Acid; (4R)-5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylic Acid; (R)-Streptonigrin. Grades: Highly Purified. CAS No. 3930-19-6. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 506.46. US Biological Life Sciences. | Worldwide |
Topiroxostat Quick inquiry Where to buy Suppliers range | Topiroxostat is a novel and potent xanthine oxidoreductase (XOR) inhibitor. Uses: Enzyme inhibitors. Synonyms: FYX051; FYX051; FYX 051; Topiroxostat. trade names Topiloric Uriadec. Grades: >98%. CAS No. 577778-58-6. Molecular formula: C13H8N6. Mole weight: 248.24. | |
Tretazicar Quick inquiry Where to buy Suppliers range | Tretazicar is an anticancer prodrug used in gene therapy research and is known to be activated by NAD(P)H Quinone Oxidoreductase 2. Group: Biochemicals. Alternative Names: 5-(1-Aziridinyl)-2,4-dinitrobenzamide; 2, 4-Dinitro-5-ethylene iminobenzamide; 2, 4-Dinitroethylene iminobenzamide; 5-(1-Aziridinyl)-2,4-dinitrobenzamide; 5-Aziridino-2,4-dinitrobenzamide; 5-Aziridinyl-2,4-dinitrobenzamide; CB 1954; NSC 115829. Grades: Highly Purified. CAS No. 21919-05-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
(Z)-Pterulinic Acid Quick inquiry Where to buy Suppliers range | (Z)-Pterulinic Acid is a Coenzyme I: Coenzyme Q oxidoreductase inhibitor produced by Pterula sp. 82168. It has anti-yeast and filamentous fungus effect and has cytotoxic activity. CAS No. 530087-05-9. Molecular formula: C15H11ClO4. Mole weight: 290.70. |