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| Product | Description | |
|---|---|---|
| Oxindole | Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Indolinone. CAS No. 59-48-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-Y0061. |  |
| Oxindole (2-Indolinone) | 25g Pack Size. Group: Building Blocks, Indoles, Research Organics & Inorganics. Formula: C8H7NO. CAS No. 59-48-3. Prepack ID 15523262-25g. Molecular Weight 133.15. See USA prepack pricing. |  |
| Oxindole-4-boronic acid,pinacol ester | Heterocyclic Organic Compound. Alternative Names: 1150271-44-5, Oxindole-4-boronic acid, pinacol ester, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one, SureCN1016712, CTK8B3930, ANW-43475, AKOS016002796, Oxindole-4-boronic acid, pinacol ester,, AK100094, A-5148. CAS No. 1150271-44-5. Molecular formula: C14H18BNO3. Mole weight: 259.1. Purity: 0.96. IUPACName: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydroindol-2-one. Canonical SMILES: B1 (OC (C (O1) (C)C) (C)C)C2=C3CC (=O)NC3=CC=C2. Catalog: ACM1150271445. |  |
| Oxindole-6-boronic acid | Heterocyclic Organic Compound. CAS No. 1217500-61-2. Molecular formula: C8H8BNO3. Mole weight: 176.9661. Purity: 0.97. Catalog: ACM1217500612. | |
| Oxindole-7-boronic acid,pinacol ester | Heterocyclic Organic Compound. Alternative Names: Oxindole-7-boronic acid, pinacol ester, 1150271-45-6, SureCN519420, CTK8B3940, ANW-43501, AKOS016001835, Oxindole-7-boronic acid, pinacol ester,, AK101036, BB 0261336, A-5149, 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one. CAS No. 1150271-45-6. Molecular formula: C14H18BNO3. Mole weight: 259.1. Purity: 0.98. IUPACName: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydroindol-2-one. Canonical SMILES: B1 (OC (C (O1) (C)C) (C)C)C2=C3C (=CC=C2)CC (=O)N3. Catalog: ACM1150271456. | |
| 1-Boc-Oxindole-5-boronic acid | 1-Boc-Oxindole-5-boronic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256345-64-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H16BNO5, Molecular Weight: 277.08. US Biological Life Sciences. |  Worldwide |
| 1-Methyl-2-oxindole (1-Methyl-2-indolone) | 1-Methyl-2-indolone is a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 61-70-1. Pack Sizes: 1g, 5g. Molecular Formula: C9H9NO. US Biological Life Sciences. | Worldwide |
| 3,3-Bis(p-hydroxyphenyl)oxindole | Oxyphenisatin, white powder. Synonyms: Oxyphenisatin. CAS No. 125-13-3. Pack Sizes: 1g, 5g. Product ID: FR-1193. M.P. 262. Mole weight: 317.34. |  Frinton Laboratories |
| 5-(2-Chloroethyl)oxindole | Heterocyclic Organic Compound. Alternative Names: 2H-Indol-2-one,5-(2-chloroethyl)-1,3-dihydro-, 118306-76-6, ACMC-1BWSW, SureCN4404868, AGN-PC-001W0G, CTK4B0629, AG-D-40594, 5-(2-CHLOROETHYL)INDOLIN-2-ONE, 2H-Indol-2-one, 5-(2-chloroethyl)-1,3-dihydro-, 5-(2-Chloroethyl)-1,3-dihydroindol-2-one;5-(2-Chloroethyl)-2-indolinone; 5-(2-Chloroethyl)-2-indolone; 5-(2-Chloroethyl)-2-oxindole;5-(2-Chloroethyl)-3H-indol-2-one; 5-(2-Chloroethyl)oxindole. CAS No. 118306-76-6. Molecular formula: C10H10ClNO. Mole weight: 195.645500 [g/mol]. Purity: 0.96. IUPACName: 5-(2-chloroethyl)-1,3-dihydroindol-2-one. Catalog: ACM118306766. | |
| 5-Chloro-2-oxindole | 5-Chloro-2-oxindole is used in the preparation of novel GSK-3 β inhibitors as anticancer agents. Group: Biochemicals. Alternative Names: 5-Chloro-1,3-dihydro-2H-indol-2-one; 5-Chloro-1,3-dihydroindol-2-one; 5-Chloro-2,3-dihydroindol-2-one; 5-Chloro-2-indolinone; 5-Chloro-2-oxindole; 5-Chloro-2-oxoindoline; 5-Chloroindol-2-one; 5-Chlorooxindole. Grades: Highly Purified. CAS No. 17630-75-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 5-Chloro-2-oxindole 98+% (HPLC) | 5-Chloro-2-oxindole 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| 5-Chloro-3-(3,4-dichlorobenzylidene)-oxindole | Heterocyclic Organic Compound. Alternative Names: 5-chloro-3-(3,4-dichloro-benzylidene)-1,3-dihydro-indol-2-one. CAS No. 114727-44-5. Molecular formula: C15H8Cl3NO. Mole weight: 324.589. Purity: 0.96. IUPACName: 5-chloro-3-(3,4-dichlorobenzylidene)-oxindole. Catalog: ACM114727445. | |
| 5-Fluoro-2-oxindole (5-Fluoro-1,3-dihydro-indol-2-one,. ) | Soulbility: Group: Biochemicals. Alternative Names: 5-Fluoro-1,3-dihydro-indol-2-one. Grades: Highly Purified. CAS No. 56341-41-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 5-Fluoro-2-oxindole 98+% (HPLC) | 5-Fluoro-2-oxindole 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| 6-Bromo-2-oxindole | 6-Bromo-2-oxindole. Group: Biochemicals. Alternative Names: 6-Bromo-1,3-dihydro-2H-indol-2-one; 6-Bromo-1,3-dihydroindol-2-one; 6-Bromo-2-indolinone. Grades: Highly Purified. CAS No. 99365-40-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H6BrNO. US Biological Life Sciences. | Worldwide |
| 6-Bromo-2-oxindole | Bromo-2-oxindole. CAS No. 99365-40-9. Categories: 6-bromooxindole. |  Pennsylvania PA |
| 6-Bromooxindole | 6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 6-Bromo-2-oxindole. CAS No. 99365-40-9. Pack Sizes: 10 g; 25 g. Product ID: HY-59227. | |
| 6-Chloro-5-(2-chloroethyl)oxindole | 6-Chloro-5-(2-chloroethyl)oxindole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 6-Chloro-5-fluoro-2-oxindole | Heterocyclic Organic Compound. CAS No. 100487-74-9. Molecular formula: C8H5ClFNO. Mole weight: 185.58. Catalog: ACM100487749. | |
| 6-Methoxy-2-oxindole | 6-Methoxy-2-oxindole. Group: Biochemicals. Grades: Highly Purified. CAS No. 7699-19-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| 6-Trifluoro methyl oxindole | 6-Trifluoro methyl oxindole. Group: Biochemicals. Grades: Highly Purified. CAS No. 1735-89-3. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C9H6F3NO. US Biological Life Sciences. | Worldwide |
| 7-Chloro-2-oxindole | 7-Chloro-2-oxindole. CAS No: 25369-33-9 |  Sarchem Laboratories New Jersey NJ |
| Diclofenac EP Impurity E (Oxindole) | Diclofenac EP Impurity E (Oxindole). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: indolin-2-one. CAS No. 59-48-3. Molecular Formula: C8H7NO. Mole Weight: 133.05. Catalog: APB59483. |  |
| (E)-FeCP-oxindole | (E)-FeCP-oxindole. Group: Biochemicals. Grades: Purified. CAS No. 884338-18-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (E)-FeCP-oxindole | (E)-FeCP-oxindole is a human vascular endothelial cell growth factor receptor 2 (VEGFR-2) inhibitor (IC50 = 214 nM). (E)-FeCP-oxindole exhibits anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Synonyms: (E)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one. CAS No. 884338-18-5. Molecular formula: C19H15FeNO. Mole weight: 329.17. |  |
| Methyl oxindole-6-carboxylate 98+% (HPLC) | Methyl oxindole-6-carboxylate 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Sumatriptan Hydroxy-Oxindole Impurity (Sumatriptan Impurity 1) | Sumatriptan Hydroxy-Oxindole Impurity (Sumatriptan Impurity 1). Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS013024. Format: Neat. Shipping: Room Temperature. | |
| Tadalafil Spiro-oxindole | Tadalafil Spiro-oxindole. Group: Biochemicals. Alternative Names: Tadalafil Impurity. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C22H19N3O5, Molecular Weight: 405.4. US Biological Life Sciences. | Worldwide |
| Tadalafil Spiro-oxindole Impurity (EP Impurity I) | | |
| (Z)-FeCP-oxindole | (Z)-FeCP-oxindole is a human vascular endothelial cell growth factor receptor 2 (VEGFR-2) inhibitor (IC50 = 220 nM). (Z)-FeCP-oxindole exhibits anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Synonyms: (Z)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one. CAS No. 1137967-28-2. Molecular formula: C19H15FeNO. Mole weight: 329.17. | |
| 1, 1'-Bis (dicyclohexylphosphino)ferrocene | Ligand for palladium-catalyzed synthesis of oxindoles by amide ?-arylation. Ligand for palladium-catalyzed alkoxycarbonylation of aryl chlorides. Ligand for ruthenium-catalyzed alcohol-allene C-C coupling reaction via hydrohydroxyalkylation of 1,1-disubstituted allenes employing alcohols. Ligand for nickel-catalyzed cross-coupling reaction of arylboronic acids with aryl carbonates. Ligand for palladium-catalyzed regiodivergent hydroesterification of aryl olefins with phenyl formate to form linear structured phenyl arylpropanoates. Ligand for palladium-catalyzed direct borylation of benzyl alcohol and its analogues in the absence of bases. Group: Organic phosphine compounds. Alternative Names: 1,1-Bis(dicyclohexylphosphino)ferrocene; 1,1-Bis(Dicyclohexylphosphino)Ferrocene; 1,1-BIS(DICYCLOHEXYLPHOSPHINO)FERROCENE. CAS No. 146960-90-9. Molecular formula: C34H52FeP2. Mole weight: 578.57. Appearance: Orange-red powder. Purity: 0.98. IUPACName: dicyclohexyl(cyclopentyl)phosphane; iron. Canonical SMILES: C1CCC (CC1)P (C2CCCCC2)[C]3[CH][CH][CH][CH]3. C1CCC (CC1)P (C2CCCCC2)[C]3[CH][CH][CH][CH]3. [Fe]. Catalog: ACM146960909. | |
| 1-Benzylindole-5-boronic Acid Pinacol Ester | 1-Benzylindole-5-boronic Acid Pinacol Ester acts as a reagent in the synthesis of 3,3-difluoro-2-oxindoles via electrophilic fluorination of indoles using N-fluoro Benzene sulfonimide. Preparation of triazolopyridine compounds as JAK kinase inhibitors useful in the treatment of neurodegenerative and inflammatory diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206163-56-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C21H24BNO2, Molecular Weight: 333.23. US Biological Life Sciences. | Worldwide |
| 1-Methyl-2-oxo-3-piperidinecarboxylic Acid | 1-Methyl-2-oxo-3-piperidinecarboxylic Acid is a reactant which was used in the copper-catalyzed preparation of spirocyclic oxindoles via a direct C-H, Ar-H functionalization. Group: Biochemicals. Grades: Highly Purified. CAS No. 37464-03-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C7H11NO3, Molecular Weight: 157.169999999999. US Biological Life Sciences. | Worldwide |
| 1-Phenyl-1H-pyrazole | 1-Phenyl-1H-pyrazole is an intermediate used to prepare heterocyclic sulfonamide γ-secretase inhibitors. It is also used in the synthesis of a 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1126-00-7. Pack Sizes: 1g, 5g. Molecular Formula: C9H8N2, Molecular Weight: 144.169999999999. US Biological Life Sciences. | Worldwide |
| 2-(2-Cyclobuten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | 2-(2-Cyclobuten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3 β inhibitors as anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 847158-88-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H17BO2. US Biological Life Sciences. | Worldwide |
| 2,2-Dichloro-3-(dimethylphenylsilyl)-cyclobutanone | 2,2-Dichloro-3-(dimethylphenylsilyl)-cyclobutanone is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3 β inhibitors as anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 847158-94-5. Pack Sizes: 500mg, 1g. Molecular Formula: C12H14Cl2OSi. US Biological Life Sciences. | Worldwide |
| 2,3-Dihydro-2-oxo-1H-indole-5-sulfonamide | 2,3-Dihydro-2-oxo-1H-indole-5-sulfonamide. Group: Biochemicals. Alternative Names: 2-Oxo-2,3-dihydro-1H-indole-5-sulfonamide; 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide; 2-Oxoindoline-5-sulfonamide; 5-Aminosulfonyl-2-indolinone; 5-Aminosulfonyl-2-oxindole. Grades: Highly Purified. CAS No. 175075-24-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2- (Benzylamino) benzonitrile | 2- (Benzylamino) benzonitrile is a general reagent used in the synthesis of 3,3-disubstituted oxindoles through Pd-catalyzed intramolecular. Group: Biochemicals. Grades: Highly Purified. CAS No. 5589-62-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H12N2, Molecular Weight: 208.26. US Biological Life Sciences. | Worldwide |
| 2-Bromobenzyl Alcohol | 2-Bromobenzyl Alcohol acts as a reagent for the synthesis of alkoxy tetrasubstituted chiral amino acids via three-component reaction of (diazo)oxindoles, alcohols and benzhydrylimino ester involving enantioselective trapping of oxonium ylides by benzhydrylimino ester. Also acts as a reagent for the preparation of orally active and liver-targeted prodrug of 5-fluoro-2'-deoxyuridine for treatment of hepatocellular carcinoma. Group: Biochemicals. Grades: Highly Purified. CAS No. 18982-54-2. Pack Sizes: 5g, 25g. Molecular Formula: C7H7BrO. US Biological Life Sciences. | Worldwide |
| 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide | 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide can be used as reactant/reagent for synthetic preparation of oxindole derivatives as inhibitors of tyrosine kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 2653-16-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9ClN2O3. US Biological Life Sciences. | Worldwide |
| (2-Cyclobuten-1-yldimethylsilyl) benzene | (2-Cyclobuten-1-yldimethylsilyl) benzene is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3 β inhibitors as anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 847158-86-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H16Si. US Biological Life Sciences. | Worldwide |
| (2-Cyclobuten-1-ylseleno)-benzene | (2-Cyclobuten-1-ylseleno)-benzene is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3 β inhibitors as anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 847158-87-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C10H10Se. US Biological Life Sciences. | Worldwide |
| 2-(Di-tert-butylphosphino)biphenyl | Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates. Ligand employed in a very active and general catalyst for Suzuki coupling reactions using aryl chlorides, bromides and triflates. Ligand used in palladium-catalyzed synthesis of oxindoles from α-chloroacetanilides. Effective ligand used in palladium-catalyzed arylation of thiazoles. Used in the formation of 2-benzylindolines via sequential palladium-catalyzed N-arylation/cyclization/C-arylation. Selective in the palladium-catalyzed arylation of silyl enol ethers formed from copper-catalyzed reduction of enones. Group: Organic phosphine compounds. Alternative Names: (2-Biphenylyl)-Di-Tert-Butylphosphine. CAS No. 224311-51-7. Molecular formula: C20H27P. Mole weight: 298.4. Appearance: Solid. Purity: 0.98. IUPACName: ditert-butyl-(2-phenylphenyl)phosphane. Canonical SMILES: CC (C) (C)P (C1=CC=CC=C1C2=CC=CC=C2)C (C) (C)C. Density: 1 g/cm3. Catalog: ACM224311517-1. | |
| (2E)?-?3-? (Dimethylamino)?-?1-? (3-?pyridyl)?prop-?2-?en-?1-?one | (2E)?-?3-? (Dimethylamino)?-?1-? (3-?pyridyl)?prop-?2-?en-?1-?one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 123367-26-0. Pack Sizes: 250mg, 5g. Molecular Formula: C10H12N2O. US Biological Life Sciences. | Worldwide |
| 3-(Dimethylphenylsilyl)-cyclobutanone | 3-(Dimethylphenylsilyl)-cyclobutanone is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3 β inhibitors as anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 847158-84-3. Pack Sizes: 250mg, 500mg. Molecular Formula: C12H16OSi. US Biological Life Sciences. | Worldwide |
| 4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one | Heterocyclic Organic Compound. Alternative Names: 4-(2-Bromoethoxy)phenylhydrazine hydrochloride;4-(2-Bromoethyl)-1,3-dihydro-2H-indolin-2-one;4-(2'-Bromoethyl)-1,3-dihydro-2H-indol-2-one;4-(2-Bromoethyl)oxindole;4-(2-Bromoethyl)-2-oxoindole. CAS No. 120427-96-5. Molecular formula: C10H10BrNO. Mole weight: 240.1. Appearance: Yellow Solid. Density: 1.528. Catalog: ACM120427965. | |
| 5-Fluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one | Heterocyclic Organic Compound. Alternative Names: 5-Fluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one, 1190314-85-2, 5-fluoro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one, 2H-Pyrrolo[2,3-b]pyridin-2-one, 5-fluoro-1,3-dihydro-, AC1Q4N2G, ACMC-209a15, CTK4B1025, MolPort-015-157-232, 5-FLUORO-7-AZA-2-OXINDOLE, ANW-17271, AKOS006333843, AG-I-03064, PB30039, QC-2918, RP09000, AK-88818, BD228472, KB-43143, AM20050701, 5-fluoro-1H,3H-pyrrolo[2,3-b]pyridin-2-one. CAS No. 1190314-85-2. Molecular formula: C7H5FN2O. Mole weight: 152.13. Purity: 0.96. IUPACName: 5-fluoro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one. Canonical SMILES: C1C2=CC(=CN=C2NC1=O)F. Catalog: ACM1190314852. | |
| 6-Bromo-1,3-dihydropyrrolo[3,2-b]pyridin-2-one | Heterocyclic Organic Compound. Alternative Names: 6-bromo-1H-pyrrolo[3,2-b]pyridin-2(3H)-one, 1190319-62-0, 6-BROMO-1,3-DIHYDROPYRROLO[3,2-B]PYRIDIN-2-ONE, SureCN660464, CTK8B6549, 6-BROMO-4-AZA-2-OXINDOLE, ANW-53643, AKOS015899190, PB24075, RP08980, AK-59555, KB-44729, QC-10551, FT-0684840, X9354, 6-bromo-1H,3H-pyrrolo[3,2-b]pyridin-2-one, C-8239, I14-12086, I14-13782, 6-BROMO-1H,2H,3H-PYRROLO[3,2-B]PYRIDIN-2-ONE. CAS No. 1190319-62-0. Molecular formula: C7H5BrN2O. Mole weight: 213.033. Purity: 0.96. IUPACName: 6-bromo-1,3-dihydropyrrolo[3,2-b]pyridin-2-one. Canonical SMILES: C1C2=NC=C(C=C2NC1=O)Br. Density: 1.768 g/cm³. Catalog: ACM1190319620. | |
| (8α, 9S)-(+)-9-Amino-cinchonan-6'-ol, min. 90% | 1. [2+3]-dipolar cycloaddition of cyclic enones. 2. Activation of α,β-unsaturated carbonyl compounds: a) vinylogous α-ketol rearrangement. b) vinylogous Michael addition of β-substituted α,β-unsaturated cyclohexanones. 3. Michael addition a) α-nitroacetate to α,β-unsaturated ketones. b) Diastereodivergent Michael addition to α-substituted, α,β-unsaturated ketones. 4. α-benzoyloxylation of α-branched aldehydes. 5. [4+2]-cycloadditions of β-substituted α,β-unsaturated cyclohexanones with polyconjugated malonitriles. 6. Vinylogous organocascade catalysis with control of remote stereochemistry in the synthesis of spirocyclic oxindoles. Group: Nitrogen-containing catalysts. Alternative Names: (8S, 9S)-9-Aminocinchonan-6'-ol;MFCD27978392;960050-59-3;(8a, 9S)-(+)-9-Amino-cinchonan-6'-ol. CAS No. 960050-59-3. Molecular formula: C19H23N3O. Mole weight: 309.413g/mol. IUPACName: 4-[(S)-amino-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]methyl]quinolin-6-ol. Canonical SMILES: C=CC1CN2CCC1CC2C (C3=C4C=C (C=CC4=NC=C3)O)N. Catalog: ACM960050593. | |
| C16 | C16 is an inhibitor of RNA-activated protein kinase (PKR) (IC50 = 210 nM). It is an imidazolo-oxindole derivative that binds to ATP-binding site of PKR and rescues PKR-dependent translation block in vitro. C16 has neuroprotective activity against cell damage in human neuroblastoma cells and neuroinflammation in acute excitotoxic rat model. Synonyms: GW-506033X; GW 506033X; GW506033X; C16, PKR Inhibitor; 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one. Grades: ≥98% by HPLC. CAS No. 608512-97-6. Molecular formula: C13H8N4OS. Mole weight: 268.29. | |
| Corynoxine | Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway [1]. Uses: Scientific research. Group: Natural products. CAS No. 6877-32-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0901. | |
| Diclofenac Amide | A potential prodrug of Diclofenac and possible impurity during its commercial synthesis. Group: Biochemicals. Alternative Names: 1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one; 1- (2, 6-Dichlorophenyl) oxindole; N-(2,6-dichlorophenyl)-2-indolinone; NSC 621845; Diclofenac Lactam; USP DIclofenac Related Compound A. Grades: Highly Purified. CAS No. 15362-40-0. Pack Sizes: 5mg, 10mg, 100mg. US Biological Life Sciences. | Worldwide |
| Esermethole | Esermethole is an analytical method that is used for the separation of racemic oxindoles. It is a powerful tool that can be used to synthesize a wide range of compounds with various functional groups and enantiomers. It also has the ability to allylate amines, which are important in the synthesis of pharmaceuticals. Esermethole is an analytical method that can be used in the preparation of samples for analysis by NMR spectroscopy, gas chromatography, or mass spectrometry. The asymmetric synthesis process involves three steps: (1) reaction of an alcohol with sodium carbonate to produce a chiral alcohol; (2) reaction of the chiral alcohol with an alkyl halide to produce a chiral acid; and (3) condensation of the chiral acid with an amine to produce the desired product. Group: Indole alkaloids. CAS No. 65166-97-4. Canonical SMILES: C[C@@]12CCN ([C@@H]1N (C3=C2C=C (C=C3)OC)C)C. Catalog: ACM65166974. | |
| (Pentamethylcyclopentadienyl)iridium (III) chloride dimer | Iridium-catalyzed C-3 alkylation of oxindole with alcohols. Precursor to N-heterocyclic carbene catalyst effective for hydrogenation and alkylation of amines and alcohols. Precursor to efficient phosphine free catalyst for enantioselective hydrogenation of quinoline derivatives. Catalyst for oxidative C-H activation. Precursor to an effective water oxidation catalyst. Group: Iridium series of catalysts. Alternative Names: Dichloro (pentamethylcyclopentadienyl)iridium (III)dimer. CAS No. 12354-84-6. Molecular formula: C20H30Cl4Ir2. Mole weight: 796.7. Appearance: Orange yellow powder. Purity: 0.99. IUPACName: iridium(3+);1,2,3,4,5-pentamethylcyclopenta-1,3-diene;tetrachloride. Canonical SMILES: C[C-]1C(=C(C(=C1C)C)C)C. C[C-]1C(=C(C(=C1C)C)C)C. [Cl-]. [Cl-]. [Cl-]. [Cl-]. [Ir+3]. [Ir+3]. Catalog: ACM12354846-1. | |
| (R)-(+)-XylBINAP | Ligand used in copper-catalyzed asymmetric Mannich-type reactions of N-acylimino esters. Ligand used in the enantioselective fluorination of oxindoles. Ligand used in [2+2+2] cycloaddition of tetraynes and hexaynes. Ligand used in the asymmetric reduction of ketone via ruthenium-catalyzed transfer hydrogenation. Asymmetric hydroboration of unsaturated imines. Group: Heterocyclic organic compound. CAS No. 137219-86-4. Molecular formula: C52H48P2. Mole weight: 734.904g/mol. IUPACName: [1-[2-bis(3,5-dimethylphenyl)phosphanylnaphthalen-1-yl]naphthalen-2-yl]-bis(3,5-dimethylphenyl)phosphane. Canonical SMILES: CC1=CC (=CC (=C1)P (C2=C (C3=CC=CC=C3C=C2)C4=C (C=CC5=CC=CC=C54)P (C6=CC (=CC (=C6)C)C)C7=CC (=CC (=C7)C)C)C8=CC (=CC (=C8)C)C)C. Catalog: ACM137219864. | |
| (S,S)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine | 1. Ligand for Copper catalyzed syn-selective Mukaiyama aldol reaction. 2. Ligand for Tin catalyzed anti-selective aldol reaction. 3. Ligand for Ytterbuim catalyzed desymmetrization of meso epoxides. 4. Ligand for Copper catalyzed enantioselective addition of terminal alkynes to imines. 5. Ligand for Scandium catalyzed enantioselective syn-selective ene reactions. 6. Ligand for Copper catalysed asymmetric alkynylation of cyclic azomethine Imines. 7. Ligand for Europium catalyzed asymmetric alpha amination. 8. Ligand for Indium catalyzed enantioselective construction of spiro-fused 2-oxindole/α -methylene-γ -butyrolactones. 9. Ligand for Copper catalyzed asymmetric azide-alkyne cycloaddition to quaternary oxindoles. 10. Ligand for Iron catalyzed enantioselective nitrene transfer to sulfides. 11. Ligand for Copper catalyzed enantioselective intramolecular propargylic amination. 12. Ligand for Copper catalyzed asymmetric hydroxylation. 13. Ligand for Scandium catalyzed dearomatization of 2-naphthols by electrophilic amination. 14. Ligand for Copper catalyzed asymmetric alkynylation of oxocarbenium ions to set diaryl tetrasubstituted stereoceters. Group: Heterocyclic organic compound. Alternative Names: BP-12297; SC-44215; 2,6-BIS[(S)-4-PHENYL-2-OXAZOLIN-2-YL]PYRIDINE; RTR-007742; BR-10750; (S,S)-2,6-Bis(4-phenyl-2-oxazolinyl)pyridine; AB1011206; AJ-35446; ANW-22713; J-010994. CAS No | |
| Sumatriptan Impurity 1 | One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Impurity 1; Sumatriptan Hydroxy-Oxindole Impurity; 1-(3-(2-(Dimethylamino)ethyl)-3-hydroxy-2-oxoindolin-5-yl)-N-methylmethane. Grades: > 95%. Molecular formula: C14H21N3O4S. Mole weight: 327.41. | |
| (S)-(-)-XylBINAP | Ligand used in copper-catalyzed asymmetric Mannich-type reactions of N-acylimino esters. Ligand used in the enantioselective fluorination of oxindoles. Ligand used in [2+2+2] cycloaddition of tetraynes and hexaynes. Ligand used in the asymmetric reduction of ketone via ruthenium-catalyzed transfer hydrogenation. Asymmetric hydroboration of unsaturated imines. Group: Heterocyclic organic compound. CAS No. 135139-00-3. Molecular formula: C52H48P2. Mole weight: 734.904g/mol. IUPACName: [1-[2-bis(3,5-dimethylphenyl)phosphanylnaphthalen-1-yl]naphthalen-2-yl]-bis(3,5-dimethylphenyl)phosphane. Canonical SMILES: CC1=CC (=CC (=C1)P (C2=C (C3=CC=CC=C3C=C2)C4=C (C=CC5=CC=CC=C54)P (C6=CC (=CC (=C6)C)C)C7=CC (=CC (=C7)C)C)C8=CC (=CC (=C8)C)C)C. Catalog: ACM135139003. | |
| Tadalafil EP Impurity I | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Synonyms: Tadalafil Spiro-oxindole Impurity; (8a'R)-6'-(1,3-Benzodioxol-5-yl)-2'-methyl-2',3',8',8a'-tetrahydro-6'H-spiro[indole-3,7'-pyrrolo[1,2-a]pyrazine]-1',2,4'(1H)-trione. Grades: > 95%. CAS No. 1795790-92-9. Molecular formula: C22H19N3O5. Mole weight: 405.41. | |
| Triphenylphosphinegold(I) bis (trifluoromethanesulfonyl)imidate, min. 98% | Catalyst promoting the addition of nucleophiles to alleneamides. Gold- and Bronsted acid-catalyzed cycloisomerization of 1,8-diynyl vinyl acetates to bicycle[2.2.1]hept-2-en-7-ones. Catalyst used for the synthesis of spiro[piperidine-3,3'-oxindoles]. Catalyst used in the gold(I)-catalyzed Rautenstrauch rearrangement. Gold-catalyzed π-directed regioselective cyclization of bis(o-alkynyl benzyl alcohols): rapid excess to dihydroisobenzofuran derivatives. Gold compound used in acid-catalyzed cycloisomerization - synthesis of diverse nitrogen-containing spiro heterocycles. Gold catalyst used in the domino synthesis of functionalized benzofurans and tetracyclic isochromans via formal carboalkoxylation. Group: Gold series of catalysts. CAS No. 866395-16-6. Molecular formula: C20H15AuF6NO4PS2. Mole weight: 739.4. Appearance: white to off-white powder. Purity: 0.99. Catalog: ACM866395166. | |
| Tris (dibenzylideneacetone)dipalladium (0) chloroform adduct | Used for Pd-catalyzed asymmetric arylation, vinylation, and Allenylation of tert-cyclobutanols via enantioselective C-C Bond cleavage. Used for synthesis of chiral chromans through the Pd-catalyzed asymmetric allylic alkylation (AAA). Catalyst for double N-arylation of primary amines to synthesize multisubstituted carbazoles from 2,2'biphenylylene ditriflates. Paladium catalyst for regioand enantioselective allylic alkylation of ketones through allyl enol carbonates. Used for Pd-catalyzed enantioselective C-3 allylation of 3-substituted-1H-indoles using trialkylboranes. Used for enantioselective construction of spirocyclic oxindolic cyclopentanes by Pd-catalyzed trimethylenemethane- [3+2]-cycloaddition. Used for Pd-catalyzed insertion of α-diazoesters into vinyl halides to generate α,β-unsaturated γ-amino Esters. Pd catalyst for decarboxylative asymmetric allylic alkylation of enol carbonates. Palladium catalyst for asymmetric addition of oxindoles and allenes. Catalyst for diastereoand enantioselective formal [3+2]-cycloaddition between substituted vinylcyclopropanes and electron-deficient olefins. Used for Pd-catalyzed asymmetric decarboxylative cycloaddition of vinylethylene carbonates with Michael sacceptors. Catalyst for enantioselective [6+4] cycloaddition of vinyl oxetanes with azadienes to access ten-membered heterocycles. Group: Palladium series | |
| Trk Inhibitor III, GNF-5837 ( (Z) -1- (3- ( (3- ( (1H-Pyrrol-2-yl) methylene) -2-oxoindolin-6-yl) amino) -4-methylphenyl) -3- (2-fluoro-5- (trifluoromethyl) phenyl) urea) | An orally bioavailable oxindole compound that and acts as a potent, reversible and type II DFG-out inhibitor of pan-Trk activity (IC50=8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC50=11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC50=42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC50=1 and 0.5uM) and Ba/F3-Tel-R and wt-Ba/F3 cells (IC50=3.0 and 5.6uM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.). Group: Biochemicals. Grades: Highly Purified. CAS No. 1033769-28-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| [(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]ferrocene | Iron Complexes. Alternative Names: (Z)-FeCP-oxindole. CAS No. 1137967-28-2. Molecular formula: C19H15FeNO. Mole weight: 329.2. Purity: 0.98. Canonical SMILES: [CH-]1C=CC=C1. C1=CC=C2C (=C1)C (=C (N2)[O-])C=C3C=CC=C3. [Fe+2]. Catalog: ACM1137967282. | |
| Mitraphylline | Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils [1]. Uses: Scientific research. Group: Natural products. CAS No. 509-80-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6946. | |
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