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Contains thiamine diphosphate. It acts not only on 3-methyl-2-oxobutanaoate, but also on 4-methyl-2-oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on the 2-oxo acids that derive from the action of transaminases on valine, leucine and isoleucine. It is a component of the multienzyme 3-methyl-2-oxobutanoate dehydrogenase complex in which multiple copies of it are bound to a core of molecules of EC 2.3.1.168, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, which also binds multiple copies of EC 1.8.1.4, dihydrolipoyl dehydrogenase. It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.168. Group: Enzymes. Synonyms: 2-oxoisocaproate dehydrogenase; 2-oxoisovalerate (lipoate) dehydrogenase; 3-methyl-2-oxobutanoate dehydrogenase (lipoamide); 3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating); α-keto-α-methylvalerate dehydrogenase; α. Enzyme Commission Number: EC 1.2.4.4. CAS No. 9082-72-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1219; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); EC 1.2.4.4; 9082-72-8; 2-oxoisocaproate dehydrogenase; 2-oxoisovalerate (lipo
The enzyme has no activating compound but is specific for its substrate. It is a mitochondrial enzyme associated with the branched-chain 2-oxoacid dehydrogenase complex. Phosphorylation inactivates EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring). Group: Enzymes. Synonyms: BCK; BCKD kinase; BCODH kinase; branched-chain α-ketoacid dehydrogenase kinase; branched-chain 2-oxo acid dehydrogenase kinase; branched-chain keto acid dehydrogenase kinase; branched-chain oxo acid dehydrogenase kinase (phosphorylating); STK2. Enzyme Commission Number: EC 2.7.11.4. CAS No. 82391-38-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3155; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase; EC 2.7.11.4; 82391-38-6; BCK; BCKD kinase; BCODH kinase; branched-chain α-ketoacid dehydrogenase kinase; branched-chain 2-oxo acid dehydrogenase kinase; branched-chain keto acid dehydrogenase kinase; branched-chain oxo acid dehydrogenase kinase (phosphorylating); STK2. Cat No: EXWM-3155.
The enzyme is CoA-dependent and contains thiamine diphosphate and iron-sulfur clusters. Preferentially utilizes 2-oxo-acid derivatives of branched chain amino acids, e.g. 3-methyl-2-oxopentanoate, 4-methyl-2-oxo-pentanoate, 2-oxobutyrate and 3-methylthiopropanamine. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.1, pyruvate synthase, and EC 1.2.7.3, 2-oxoglutarate synthase. Group: Enzymes. Synonyms: 2-ketoisovalerate ferredoxin reductase; 3-methyl-2-oxobutanoate synthase (ferredoxin); VOR; branched-chain ketoacid ferredoxin reductase; branched-chai. Enzyme Commission Number: EC 1.2.7.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1230; 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); EC 1.2.7.7; 2-ketoisovalerate ferredoxin reductase; 3-methyl-2-oxobutanoate synthase (ferredoxin); VOR; branched-chain ketoacid ferredoxin reductase; branched-chain oxo acid ferredoxin reductase; keto-valine-ferredoxin oxidoreductase; ketoisovalerate ferredoxin reductase; 2-oxoisovalerate ferredoxin reductase. Cat No: EXWM-1230.
3-methyl-2-oxobutanoate hydroxymethyltransferase
This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the hydroxymethyl-, formyl- and related transferases. This enzyme participates in pantothenate and coa biosynthesis. Group: Enzymes. Synonyms: α-ketoisovalerate hydroxymethyltransferase; dehydropantoate hydroxymethyltransferase; ketopantoate hydroxymethyltransferase; oxopantoate hydroxymethyltransferase; 5,10-methylene tetrahydrofolate:α-ketoisovalerate hydroxymethyltransferase. Enzyme Commission Number: EC 2.1.2.11. CAS No. 56093-17-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2002; 3-methyl-2-oxobutanoate hydroxymethyltransferase; EC 2.1.2.11; 56093-17-5; α-ketoisovalerate hydroxymethyltransferase; dehydropantoate hydroxymethyltransferase; ketopantoate hydroxymethyltransferase; oxopantoate hydroxymethyltransferase; 5,10-methylene tetrahydrofolate:α-ketoisovalerate hydroxymethyltransferase. Cat No: EXWM-2002.
Coenzyme A S-(2-Ethyl-3-oxobutanoate). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C27H44N7O18P3S, Molecular Weight: 879.6. US Biological Life Sciences.
Worldwide
Coenzyme A S-(2-Ethyl-3-oxobutanoate)
Coenzyme A S-(2-Ethyl-3-oxobutanoate) is an derivative of Coenzyme A, a cofactor in enzymatic acetyl transfer reactions. Molecular formula: C27H44N7O18P3S. Mole weight: 879.6.
(R)-tert-Butyl 4-(((((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methoxy)sulfonyl)amino)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoate is an important compound in the field of biomedicine, as it is revered for its ability to specifically inhibit enzymes crucial for the replication of cancer and virus cells. Its usage is not limited to fighting diseases but also holds enormous potential to study the underlying mechanisms of cancer and viral growth, paving the way for the development of new therapies that cater to the complex needs of the patients, which is highly significant. Synonyms: (R)-4-(((((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuran[3,4-d]-Tert-butyl] [1,3]dioxol-4-yl)methoxy)sulfonyl)amino)-3-((tert-butoxycarbonyl)amino)-4-oxobutane acid. Molecular formula: C26H39N7O11S. Mole weight: 657.69.
Sodium 2-oxobutanoate
Sodium 2-oxobutanoate is an organic compound commonly used as a food additive and industrial raw material. It can be used as an acidity regulator, leavening agent and preservative, and is often used in the fields of bread, baked goods and canning. In addition, the compound is used in the production of certain industrial products, such as in plastics, textiles and dyes. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2013-26-5. Pack Sizes: 1 g; 5 g. Product ID: HY-W005355.
Sodium 2-oxobutanoate-13C4,d2 hydrate
Sodium 2-oxobutanoate-13C4,d2 (hydrate) is the deuterium and 13C labeled Sodium 2-oxobutanoate hydrate. Group: Isotope-labeled synthetic intermediates. CAS No. 1049736-26-6. Molecular formula: 13C4H5D2NaO4. Mole weight: 148.07. Canonical SMILES: [13CH3][13C] ([2H]) ([13C] ([13C] (O[Na])=O)=O)[2H]. O. Catalog: ACM1049736266.
2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester is an intermediate in the synthesis of Lercanidipine, which is a dihydropyridine calcium channel blocker. Synonyms: 1-((3,3-diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl 2-(3-nitrobenzylidene)-3-oxobutanoate; Butanoic acid, 2-[(3-nitrophenyl)methylene]-3-oxo-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl ester; 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl 2-[(3-nitrophenyl)methylene]-3-oxobutanoate. CAS No. 210579-45-6. Molecular formula: C31H34N2O5. Mole weight: 514.61.
2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid Propyl Ester is an intermediate in the synthesis of Lercanidipine, which is a dihydropyridine calcium channel blocker. Synonyms: Propyl (3-Nitrobenzylidene)acetoacetate; Propyl 2-(3-Nitrobenzylidene)-3-oxobutanoate; Butanoic Acid, 2-[(3-Nitrophenyl)Methylene]-3-Oxo-, Propyl Ester. CAS No. 77888-04-1. Molecular formula: C14H15NO5. Mole weight: 277.27.
2-Acetylbutanoic-d5 Acid Ethyl Ester. Group: Biochemicals. Alternative Names: Ethyl 2-Acetylbutanoate-d5; Ethyl 2-Ethyl-d5-3-oxobutanoate; Ethyl 2-Ethyl-d5-3-oxobutyrate; Ethyl 2-Ethyl-d5-3-ketobutyrate;Ethyl 2-Ethylacetylacetate-d5. Grades: Highly Purified. CAS No. 141327-44-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
2-dehydro-3-deoxy-phosphogluconate aldolase
The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D-galactonate. cf. EC 4.1.2.55, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase. Also acts on 2-oxobutanoate. Group: Enzymes. Synonyms: phospho-2-keto-3-deoxygluconate aldolase; KDPG aldolase; phospho-2-keto-3-deoxygluconic aldolase; 2-keto-3-deoxy-6-phosphogluconic aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; 6-phospho-2-keto-3-deoxygluconate aldolase; ODPG aldolase; 2-oxo-3-deoxy-6-phosphogluconate aldolase; 2-. Enzyme Commission Number: EC 4.1.2.14. CAS No. 9024-53-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4854; 2-dehydro-3-deoxy-phosphogluconate aldolase; EC 4.1.2.14; 9024-53-7; phospho-2-keto-3-deoxygluconate aldolase; KDPG aldolase; phospho-2-keto-3-deoxygluconic aldolase; 2-keto-3-deoxy-6-phosphogluconic aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; 6-phospho-2-keto-3-deoxygluconate aldolase; ODPG aldolase; 2-oxo-3-deoxy-6-phosphogluconate aldolase; 2-keto-3-deoxygluconate-6-P-aldolase; 2-keto-3-deoxygluconate-6-phosphate aldolase; 2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase; 2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming). Cat No: EXWM-4854.
2-isopropylmalate synthase
Requires K+. Group: Enzymes. Synonyms: 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating); α-isopropylmalate synthetase; α-isopropylmalate synthase; α-isopropylmalic synthetase; isopropylmalate synthase; isopropylmalate synthetase. Enzyme Commission Number: EC 2.3.3.13. CAS No. 9030-98-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2314; 2-isopropylmalate synthase; EC 2.3.3.13; 9030-98-2; 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating); α-isopropylmalate synthetase; α-isopropylmalate synthase; α-isopropylmalic synthetase; isopropylmalate synthase; isopropylmalate synthetase. Cat No: EXWM-2314.
2-Methylacetoacetyl CoA
2-Methylacetoacetyl CoA is an intermediate in the catabolic pathway of isoleucine. Synonyms: S-2-Methylacetoacetate Coenzyme A; 2-Methylthio-acetoacetic Acid S-Ester With Coenzyme A; 2-Methylacetoacetyl Coenzyme A; S-(2-Methyl-3-oxobutanoate) Coenzyme A. CAS No. 6712-1-2. Molecular formula: C26H42N7O18P3S. Mole weight: 865.63.
2-oxoacid oxidoreductase (ferredoxin)
Contains thiamine diphosphate and [4Fe-4S] clusters. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For example, see EC 1.2.7.3, 2-oxoglutarate synthase and EC 1.2.7.7, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin). Group: Enzymes. Synonyms: OFOR. Enzyme Commission Number: EC 1.2.7.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1225; 2-oxoacid oxidoreductase (ferredoxin); EC 1.2.7.11; OFOR. Cat No: EXWM-1225.
The enzyme contains thiamine diphosphate and two [4Fe-4S] clusters. Highly specific for 2-oxoglutarate. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.1, pyruvate synthase and EC 1.2.7.7, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin). Group: Enzymes. Synonyms: 2-ketoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin oxidoreductase; KGOR; 2-oxoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating). Enzyme Commission Number: EC 1.2.7.3. CAS No. 37251-05-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1226; 2-oxoglutarate synthase; EC 1.2.7.3; 37251-05-1; 2-ketoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin oxidoreductase; KGOR; 2-oxoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating). Cat No: EXWM-1226.
3-Bromo-2-oxobutanoic Acid Methyl Ester
3-Bromo-2-oxobutanoic Acid Methyl Ester. Group: Biochemicals. Alternative Names: Methyl 3-Bromo-2-oxobutanoate; Methyl 3-Bromo-2-oxobutyrate; 3-Bromo-2-oxo-butyric Acid Methyl Ester. Grades: Highly Purified. CAS No. 34329-73-2. Pack Sizes: 1g. Molecular Formula: C5H7BrO3, Molecular Weight: 195.01. US Biological Life Sciences.
3-Oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester is an intermediate in the synthesis of Lercanidipine, which is a dihydropyridine calcium channel blocker. Synonyms: Butanoic acid, 3-oxo-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl ester; 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate; 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl 3-oxobutanoate. Grades: ≥95%. CAS No. 100427-51-8. Molecular formula: C24H31NO3. Mole weight: 381.51.
Isotope labelled 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones. Group: Biochemicals. Alternative Names: 3-Oxobutanoic Acid Methyl-d3 Ester; Methyl-d3 3-Oxobutanoate ; Acetoacetate methyl-d3 Ester; Methyl-d3 3-Oxobutyrate. Grades: Highly Purified. CAS No. 107694-22-4. Pack Sizes: 10mg. US Biological Life Sciences.
4-(4-Bromo-phenyl)-4-oxo-butyric acid methyl ester. Group: Biochemicals. Alternative Names: Methyl 4-(4-bromophenyl)-4-oxobutanoate. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
4-Cyclobutyl-3-oxo-butyric acid ethyl ester
4-Cyclobutyl-3-oxo-butyric acid ethyl ester. Group: Biochemicals. Alternative Names: Ethyl 4-cyclobutyl-3-oxobutanoate. Grades: Highly Purified. CAS No. 885280-12-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
4-Cyclohexyl-3-oxo-butyric acid ethyl ester
4-Cyclohexyl-3-oxo-butyric acid ethyl ester. Group: Biochemicals. Alternative Names: Ethyl 4-cyclohexyl-3-oxobutanoate. Grades: Highly Purified. CAS No. 64127-44-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
4-Cyclopentyl-3-oxo-butyric acid ethyl ester
4-Cyclopentyl-3-oxo-butyric acid ethyl ester. Group: Biochemicals. Alternative Names: Ethyl 4-cyclopentyl-3-oxobutanoate. Grades: Highly Purified. CAS No. 68104-99-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
4-hydroxy-2-oxoheptanedioate aldolase
Requires Co2+ or Mn2+ for activity. The enzyme is also able to catalyse the aldol cleavage of 4-hydroxy-2-oxopentanoate and 4-hydroxy-2-oxohexanoate, and can use 2-oxobutanoate as carbonyl donor, with lower efficiency. In the reverse direction, is able to condense a range of aldehyde acceptors with pyruvate. The enzyme from the bacterium Escherichia coli produces a racemic mixture of (4R)- and (4S)-hydroxy-2-oxoheptanedioate. Group: Enzymes. Synonyms: 2,4-dihydroxyhept-2-enedioate aldolase; HHED aldolase; 4-hydroxy-2-ketoheptanedioate aldolase; HKHD aldolase; HpcH; HpaI; 4-hydroxy-2-oxoheptanedioate succinate semialdehyde lyase (pyruvate-forming). Enzyme Commission Number: EC 4.1.2.52. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4889; 4-hydroxy-2-oxoheptanedioate aldolase; EC 4.1.2.52; 2,4-dihydroxyhept-2-enedioate aldolase; HHED aldolase; 4-hydroxy-2-ketoheptanedioate aldolase; HKHD aldolase; HpcH; HpaI; 4-hydroxy-2-oxoheptanedioate succinate semialdehyde lyase (pyruvate-forming). Cat No: EXWM-4889.
acetolactate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in butanoate metabolism and c5-branched dibasic acid metabolism. Group: Enzymes. Synonyms: α-acetolactate decarboxylase; (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase; (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]; (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(3R)-3-hydroxybutan-2-one-forming]. Enzyme Commission Number: EC 4.1.1.5. CAS No. 9025-2-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4795; acetolactate decarboxylase; EC 4.1.1.5; 9025-02-9; α-acetolactate decarboxylase; (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase; (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]; (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(3R)-3-hydroxybutan-2-one-forming]. Cat No: EXWM-4795.
acetolactate synthase
This enzyme requires thiamine diphosphate. The reaction shown is in the pathway of biosynthesis of valine; the enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine. Group: Enzymes. Synonyms: α-acetohydroxy acid synthetase; α-acetohydroxyacid synthase; α-acetolactate synthase; α-acetolactate synthetase; acetohydroxy acid synthetase; acetohydroxyacid synthase; acetolactate pyruvate-lyase (carboxylating); acetolactic synthetase. Enzyme Commission Number: EC 2.2.1.6. CAS No. 9027-45-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2033; acetolactate synthase; EC 2.2.1.6; 9027-45-6; α-acetohydroxy acid synthetase; α-acetohydroxyacid synthase; α-acetolactate synthase; α-acetolactate synthetase; acetohydroxy acid synthetase; acetohydroxyacid synthase; acetolactate pyruvate-lyase (carboxylating); acetolactic synthetase. Cat No: EXWM-2033.
acireductone synthase
This bifunctional enzyme first enolizes the substrate to form the intermediate 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate, which is then dephosphorylated to form the acireductone 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one. The acireductone represents a branch point in the methione-salvage pathway as it is used in the formation of formate, CO and 3-(methylthio)propanoate by EC 1.13.11.53 [acireductone dioxygenase (Ni2+-requiring)] and of formate and 4-methylthio-2-oxobutanoate either by a spontaneous reaction under aerobic conditions or by EC 1.13.11.54 {acireductone dioxygenase [iron(II)-requiring]}. Group: Enzymes. Synonyms: E1; E-1 enolase-phosphatase. Enzyme Commission Number: EC 3.1.3.77. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3682; acireductone synthase; EC 3.1.3.77; E1; E-1 enolase-phosphatase. Cat No: EXWM-3682.
Agomelatine Impurity 31
Agomelatine Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 4-(4-methoxyphenyl)-4-oxobutanoate. CAS No. 15118-67-9. Molecular Formula: C13H16O4. Mole Weight: 236.10. Catalog: APB15118679.
AHU-377 hemicalcium salt
LCZ696 is a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). Oral administration of LCZ696 caused dose-dependent increases in atrial natriuretic peptide immunoreactivity (due to NEP inhibition) in Sprague-Dawley rats and provided sustained, dose-dependent blood pressure reductions in hypertensive double-transgenic rats. In healthy participants, a randomized, double-blind, placebo-controlled study (n = 80) of single-dose (200-1200 mg) and multiple-dose (50-900 mg once daily for 14 days) oral administration of LCZ696 showed that peak plasma concentrations were reached rapidly for valsartan (1.6-4.9 hours), AHU377 (0.5-1.1 hours), and its active moiety, LBQ657 (1.8-3.5 hours). LCZ696 is superior to valsartan alone in reducing blood pressure. Preliminary results from a Phase II trial showed that LCZ696 reduced NT-proBNP to a greater extent than valsartan alone, and in addition LCZ696 had beneficial effects on symptoms. Synonyms: calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; AHU337; AHU-337; AHU 337; LCZ696; LCZ 696; LCZ696; Sacubitril. Grades: >98%. CAS No. 1369773-39-6. Molecular formula: C24H28NO5-. Mole weight: 410.48.
alanine-glyoxylate transaminase
A pyridoxal-phosphate protein. With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. A second component also catalyses the reaction of EC 2.6.1.51 serine-pyruvate transaminase. Group: Enzymes. Synonyms: AGT; alanine-glyoxylate aminotransferase; alanine-glyoxylic aminotransferase; L-alanine-glycine transaminase. Enzyme Commission Number: EC 2.6.1.44. CAS No. 9015-67-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2885; alanine-glyoxylate transaminase; EC 2.6.1.44; 9015-67-2; AGT; alanine-glyoxylate aminotransferase; alanine-glyoxylic aminotransferase; L-alanine-glycine transaminase. Cat No: EXWM-2885.